... with host cellular processes to find therapeutic approaches. New data suggest that lipid metabolism may play a significant role in regulating the response of immune cells like macrophages to viral infection, thereby affecting the outcome of the disease. Therefore, understanding the role of lipid metabolism...

... the metabolic implications of this mutation will aid to establish its wider impact on cellular behaviour and potentially inform clinical decisions. However, to date, alterations in lipid metabolism induced by APC mutations remain unclear. Intestinal organoids have gained widespread popularity in studying...

... using GraphPad Prism. Errors are based on counting statistics and error bars are not shown if they are smaller than symbol sizes. Apolipoprotein-D Ligand binding lipids Lipocalin oligomerization small-angle scattering Apolipoprotein-D (apoD) is a ∼25 kDa glycoprotein belonging...

...Ling Pan; Yun-Hua Liao; Man-Qiu Mo; Qing-Hui Zhang; Rui-Xing Yin The relationship between serum lipid profiles and related clinicopathologic features of IgA nephropathy (IgAN) and c-Maf-inducing protein ( CMIP ) gene polymorphisms is unclear. The present study was designed to examine the effect...

... to be transported and acting in concert. lipids Long-distance signaling nucleic acids phloem plant development and stress response proteins Correspondence: Susanne Hoffmann-Benning ( [email protected] ) 28 04 2020 16 09 2020 18 09 2020 21 09 2020 © 2020 The Author(s...

.... There are several regio- and stereo-isomers of HODE, and their concentrations in vivo are higher than those of other lipids. Although conformational isomers may have different biological activities, comparative analysis of intracellular function of HODE isomers has not yet been performed. We evaluated...

... AqNH 4 COOH (70:20:10)] was linearly increased to 30% over 5 min, then to 80% over 5 min, then to 100% over 5 min, and was held constant at 100% for 5 min. At last, the column was equilibrated for 9 min. Lipid extraction was performed using a modified Bligh and Dyer [ 31 ] method. For each...

...Qing-Hui Zhang; Rui-Xing Yin; Wu-Xian Chen; Xiao-Li Cao; Yu-Ming Chen Little is known about the association of the TIMD4 (T-cell immunoglobulin and mucin domain 4 gene)- HAVCR1 (hepatitis A virus cellular receptor 1) variants and lipid metabolism, the risk of coronary heart disease (CHD...

... communication investigates the effects of the mutation N215S in FD on the trafficking and processing of lysosomal GAA and their potential association with alterations in the membrane lipid composition. Abnormalities in lipid rafts (LRs) were observed in fibroblasts isolated from a male patient with FD bearing...

...-wide association study), but the association of TMEM57 rs873308 SNP and serum lipid levels has not been previously reported. The current study was undertaken to detect the association of the TMEM57 rs873308 SNP and several environmental factors with serum lipid profiles in the Han Chinese and Mulao...

..., and anabolic pathways that provide precursors for the synthesis of lipids, proteins and DNA. The review will discuss the original ideas of Otto Warburg and how they initially led to the notion that mitochondria of tumour cells were dysfunctional. Data will be presented to show that not only the organelles...