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Keywords: lncRNA
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Biosci Rep (2021) 41 (10): BSR20210908.
Published: 12 October 2021
...)-related long noncoding RNAs (lncRNAs) in urinary exosomes in NSCLC patients and normal controls to diagnose lung cancer. Methods: A differential expression analysis between NSCLC patients and healthy controls was performed using microarrays. Gene ontology (GO) term and Kyoto Encyclopedia of Genes...
Includes: Supplementary data
Articles
Biosci Rep (2021) 41 (7): BSR20211115.
Published: 12 July 2021
...Minghui Wang; Zhijun Zhang; Deng Pan; Zhigang Xin; Fan Bu; Yue Zhang; Qingwu Tian; Xiaodong Feng Background: Colorectal cancer (CRC) is one of the most common and significant malignant diseases worldwide. In the present study, we evaluated two long non-coding RNAs (lncRNAs) in CRC patients...
Includes: Supplementary data
Articles
Biosci Rep (2021) 41 (4): BSR-20190724_EOC.
Published: 07 April 2021
... © 2021 The Author(s). 2021 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . Colorectal cancer EMT lncRNA The Editorial Office has been made aware...
Articles
Biosci Rep (2021) 41 (3): BSR20201810.
Published: 15 March 2021
...Liang Zou; Peng-fei Xia; Lei Chen; Yan-yan Hou Long non-coding RNAs (lncRNAs) have been ascertained as vital modulators in abdominal aortic aneurysm (AAA) development. In this research, the function and molecular mechanisms of the lncRNA X-inactive specific transcript ( XIST ) in the evolution...
Articles
Biosci Rep (2020) 40 (12): BSR20202463.
Published: 02 December 2020
...Faping Li; Hui Guo; Bin Liu; Nian Liu; Zhixiang Xu; Yishu Wang; Honglan Zhou Bladder cancer (BC) is the most common tumor of the urinary tract. Increasing evidence showed that long non-coding RNA (lncRNA) is a critical regulator in cancer development and progression. However, the functions...
Includes: Supplementary data
Articles
Biosci Rep (2020) 40 (10): BSR20201111.
Published: 30 October 2020
... The Author(s). 2020 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . Glioma stem cells let-7g-5p lncRNA MAP3K1 NEAT1 Temozolomide As the most common...
Articles
Biosci Rep (2020) 40 (7): BSR20201524.
Published: 24 July 2020
...Hui Wang; Huichao Gong; Yingwu Liu; Limin Feng The severity and complexity evaluation of coronary artery disease in patients with coronary heart disease (CHD) require objective and accurate prognosis indexes. We assessed the relationship between lncRNA-Ang362 and prognosis of CHD patients after...
Articles
Biosci Rep (2020) 40 (7): BSR20194468.
Published: 17 July 2020
... This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . cancer LncRNA meta-analysis prognosis SNHG15 The cancers have attracted the attention of researchers due...
Includes: Supplementary data
Articles
Biosci Rep (2020) 40 (7): BSR20200442.
Published: 30 June 2020
... access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . head and neck squamous cell carcinoma lncRNA mRNA signature survival Worldwide, head and neck squamous cell carcinoma...
Articles
Biosci Rep (2020) 40 (2): BSR20190804.
Published: 11 February 2020
... were assessed and in vivo study were performed to determine the tumor suppressive effect of β-elemene and explore the molecular mechanisms. Results: β-Elemene significantly suppressed the viability of DLBCL cells, and β-elemene down-regulated the lncRNA HULC expression and regulated key pro-apoptotic...
Articles
Biosci Rep (2020) 40 (1): BSR20191731.
Published: 24 January 2020
... constructed using permutation tests and differentially expressed mRNAs, miRNAs and lncRNAs. Candidate ICM susceptible genes were screened out as differentially expressed genes in significantly differentially expressed ceRNA triplets enriched in ICM-related functional classes. Finally, eight ICM susceptibility...
Articles
Biosci Rep (2020) 40 (1): BSR20191251.
Published: 06 January 2020
... RNAs (lncRNAs) are essential in osteosarcoma processes and development, and here we report significant lncRNAs to aid in earlier diagnosis of osteosarcoma. Methods: A univariate Cox proportional hazards regression analysis and a multivariate Cox regression analysis were used to analyze osteosarcoma...
Includes: Supplementary data
Articles
Biosci Rep (2020) 40 (1): BSR20192523.
Published: 02 January 2020
...Mei Han; Lianghui You; Yanting Wu; Nan Gu; Yan Wang; Xiaodan Feng; Lanlan Xiang; Yajun Chen; Yu Zeng; Tianying Zhong Insulin resistance (IR) has been considered as the common pathological basis and developmental driving force for most metabolic diseases. Long noncoding RNAs (lncRNAs) have emerged...
Includes: Supplementary data
Articles
Biosci Rep (2019) 39 (11): BSR20182224.
Published: 22 November 2019
...Chenghan Wu; Hailong Song; Yinzhou Wang; Lili Gao; Yali Cai; Qiong Cheng; Yanru Chen; Zheng Zheng; Yuansheng Liao; Jushan Lin; Buni Xie; Weiwu Cai; Shiju Li; Lianming Liao; Xiaohua Yan We performed long non-coding RNA (lncRNA) microarray assay to identify lncRNAs with differential expression...
Includes: Supplementary data
Articles
Biosci Rep (2019) 39 (11): BSR20192453.
Published: 12 November 2019
...), is considered to be an important marker of metabolic reprogramming and one of the key enzymes. Recently, through the continuous development of genome-wide analysis and functional studies, accumulating evidence has demonstrated that long non-coding RNAs (LncRNAs) play vital regulatory roles in cancer progression...
Articles
Biosci Rep (2019) 39 (9): BSR20190903.
Published: 13 September 2019
...Chun-Ling Yu; Xiao-Ling Xu; Fang Yuan LINC00511 is a newly identified lncRNA that is up-regulated in many types of human cancers and may serve as an oncogenic lncRNA. However, there was no report about the role of LINC00511 in cervical cancer. Therefore, we investigated the clinical value...
Articles
Biosci Rep (2019) 39 (9): BSR20190489.
Published: 03 September 2019
...Exian Mou; Hao Wang Triple-negative breast cancer (TNBC) is a subtype of aggressive breast cancer with high recurrence and poor survival. Emerging evidence has indicated that long non-coding RNAs (lncRNAs) play pivotal roles in the development and progression of multiple cancers. Although...
Articles
Biosci Rep (2019) 39 (8): BSR20190590.
Published: 28 August 2019
... years, long non-coding RNAs (lncRNAs), which affect the occurrence and development of tumors through a variety of mechanisms, have become a popular research topic. LncRNAs have been found to influence radiosensitivity by regulating various mechanisms, including DNA damage repair, cell cycle arrest...
Articles
Biosci Rep (2019) 39 (7): BSR20190724.
Published: 05 July 2019
...Ying Meng; Feng Yu Although numerous differential long noncoding RNAs (IncRNAs) have been identified, the relationship between lncRNA and colorectal cancer (CRC) still remains largely unclear. In the present study, we investigated the function and provided a possible mechanism of lncRNA FAM3D-AS1...
Articles
Biosci Rep (2019) 39 (6): BSR20191202.
Published: 25 June 2019
...Changlong Shi; Li Sun; Yongsheng Song Long noncoding RNAs (LncRNAs) refer to the RNA with a length of >200 nucleotides, which lack or have no open reading coding frame and have higher tissue and organ specificity compared with the protein coding genes. A surging number of studies have shown...
Articles
Biosci Rep (2019) 39 (5): BSR20190602.
Published: 17 May 2019
...Jingxiu Zhang; Tianzhao Hou; Xueliang Qi; Jihong Wang; Xiangguo Sun LncRNA SOX21 antisense RNA 1 (SOX21-AS1) dysregulated in many types of human cancer, and functioned as tumor suppressor or promoter depending on tumor types. However, there was no report about the role of SOX21-AS1...
Articles
Biosci Rep (2019) 39 (4): BSR20182506.
Published: 30 April 2019
...Qunchang Zhang; Yongtao Zhang; Ying Wang Gastric carcinoma proliferation enhancing transcript 1 (GHET1) has been suggested to serve as a promising oncogenic lncRNA in various types of human cancer. However, the role of GHET1 remained unknown in cervical cancer. In our study, we found GHET1...
Articles
Biosci Rep (2019) 39 (4): BSR20190447.
Published: 30 April 2019
...Si Chen; Weiguo Li; Ai Guo lncRNA LOXL1 antisense RNA 1 (lncRNA LOXL1-AS1) was recently found to function as oncogenic lncRNA in glioblastoma, prostate cancer, and medulloblastoma. The role of LOXL1-AS1 in osteosarcoma was still unknown. In our study, we found LOXL1-AS1 expression levels were...
Articles
Biosci Rep (2019) 39 (4): BSR20180995.
Published: 26 April 2019
...Congmin Liu; Jing Jin; Jin Shi; Liqun Wang; Zhaoyu Gao; Tiantian Guo; Yutong He Background: Urothelial carcinoma associated 1 (UCA1), a novel long noncoding RNA (lncRNA) which is first discovered in 2006 in human bladder cancer and has become a hot spot in recent years. UCA1 has been demonstrated...
Articles
Biosci Rep (2019) 39 (4): BSR20181783.
Published: 02 April 2019
... of the aberrant expression of long noncoding RNAs (lncRNAs) with the development and progression of atherosclerosis is well known; however, it is not well investigated in hypoxic VSMCs. Using a microarray approach, we identified 1056 and 2804 differentially expressed lncRNAs and mRNAs, respectively, in hypoxic...
Includes: Supplementary data
Articles
Biosci Rep (2019) 39 (3): BSR20181937.
Published: 15 March 2019
...Xian-Ping Cui; Chuan-Xi Wang; Zhi-Yi Wang; Jian Li; Ya-Wen Tan; Song-Tao Gu; Cheng-Kun Qin LncRNA TP73 antisense RNA 1T (TP73-AS1) plays an important role in human malignancies. However, the levels of TP73-AS1 and its functional mechanisms in pancreatic cancer metastasis remain unknown...
Includes: Supplementary data
Articles
Biosci Rep (2019) 39 (2): BSR20181284.
Published: 15 February 2019
...Liuhong Zheng; Yuhan Zhang; Yajun Fu; Hangdi Gong; Jianjun Guo; Kangjing Wu; Qiaojun Jia; Xianfeng Ding The human genome transcribes a large amount of non-coding RNAs, including long non-coding RNAs (lncRNAs) and microRNAs. LncRNAs and microRNAs have been shown to play a critical regulatory role...
Includes: Supplementary data
Articles
Biosci Rep (2018) 38 (6): BSR20181223.
Published: 28 November 2018
...Kainan Wang; Xuelu Li; Chen Song; Man Li Background: LncRNA AWPPH is a recently identified critical player in the development of several types of human malignancies, our study aimed to investigate the role of AWPPH in triple-negative breast cancer. Methods: In the present study, expression of AWPPH...
Articles
Biosci Rep (2018) 38 (6): BSR20180620.
Published: 21 November 2018
...Zhen Zhang; Lifeng Feng; Pengfei Liu; Wei Duan Increasing evidence indicates that long non-coding RNAs (lncRNAs) antisense non-coding RNA in the INK4 locus (ANRIL) has been involved in various diseases and promotes tumorigenesis and cancer progression as an oncogenic gene. However, the effect...
Includes: Supplementary data
Articles
Biosci Rep (2018) 38 (5): BSR20180626.
Published: 05 October 2018
... the mechanisms of the Tanshinone IIA (Tan IIA)-induced apoptosis of FLS from patients with RA (termed RAFLS). Cell Counting Kit-8 (CCK-8) assay and Annexin V staining revealed that RAFLS viability decreased and apoptosis increased after Tan IIA treatment. Long non-coding RNA (lncRNA) GAS5 expression...
Includes: Supplementary data
Articles
Biosci Rep (2018) 38 (5): BSR20180677.
Published: 02 October 2018
... prediction revealed putative miR-26a-binding sites within TUG1 transcripts. In conclusion, our study suggests that long non-coding RNA (lncRNA) TUG1 acts as a functional oncogene in PCa development. Correspondence : Zhixin Wang ( zhangtang1617@163.com ) * These authors contributed equally...
Articles
Biosci Rep (2018) 38 (5): BSR20180566.
Published: 28 September 2018
...Bin Yang; Ge Gao; Zhixin Wang; Daju Sun; Xin Wei; Yanan Ma; Youpeng Ding Long non-coding RNAs (lncRNAs) are a class of ncRNAs with >200 nts in length that regulate gene expression. The HOXA transcript at the distal tip (HOTTIP) lncRNA plays an important role in carcinogenesis, however...
Articles
Biosci Rep (2018) 38 (5): BSR20180862.
Published: 12 September 2018
...Yanyan Shen; Erjie Xia; Adheesh Bhandari; Xiaohui Wang; Guilong Guo Evidence has been provided that long noncoding RNAs (LncRNAs) play major roles in affecting essential physiological processes, and many of which seem to have functional roles in tumorigenesis and progression. However, the intrinsic...
Articles
Biosci Rep (2018) 38 (4): BSR20180365.
Published: 31 July 2018
...Xin Huang; Weiyue Zhang; Zengwu Shao Several studies have suggested that long non-coding RNA (lncRNA) gene polymorphisms are associated with cancer risk. In the present study, we conducted a meta-analysis related to studies on the association between lncRNA single-nucleotide polymorphisms (SNPs...
Includes: Supplementary data
Articles
Biosci Rep (2018) 38 (3): BSR20180169.
Published: 21 June 2018
...Xuefang Liu; Xinliang Ming; Wei Jing; Ping Luo; Nandi Li; Man Zhu; Mingxia Yu; Chunzi Liang; Jiancheng Tu Increasing studies are indicating that long non-coding RNA (lncRNA) X-inactive specific transcript (XIST) is associated with the prognosis of cancer patients. However, the results have been...
Articles
Biosci Rep (2018) 38 (3): BSR20180475.
Published: 15 May 2018
...Haifan Yang; Ge Li; Bo Cheng; Rui Jiang Long non-coding RNA (lncRNA) ZFAS1 (zinc finger antisense 1) has been suggested to have an oncogenic role in the tumorigenesis of human malignant tumors. However, the expression status and biological function of ZFAS1 in bladder cancer is still unknown. Thus...
Articles
Biosci Rep (2018) 38 (2): BSR20171350.
Published: 27 April 2018
..., and year-round estrus. However, little is known about the molecular mechanisms underlying HP in Hu sheep. To explore the potential mRNAs and long non-coding RNAs (lncRNAs) involved in Hu sheep prolificacy, we performed an ovarian genome-wide analysis of mRNAs and lncRNAs during the follicular stage using...
Includes: Supplementary data
Articles
Biosci Rep (2018) 38 (2): BSR20171193.
Published: 20 April 2018
...Hongwei Ma; Tianshi Ma; Miao Chen; Zigui Zou; Zhihong Zhang Pseudogenes were once regarded as transcriptionally inactive and without specific molecular function. However, current evidence shows that pseudogene-derived long non-coding RNAs (lncRNAs) may be crucial regulators of human cancer...
Articles
Biosci Rep (2018) 38 (1): BSR20171664.
Published: 02 February 2018
...Dawei Xu; Jian Yu; Guojun Gao; Guangjian Lu; Yi Zhang; Pengju Ma Long noncoding RNA (lncRNA) differentiation antagonizing nonprotein coding RNA (DANCR) plays important regulatory roles in many solid tumors. However, the effect of DANCR in glioma progression and underlying molecular mechanisms were...
Articles
Biosci Rep (2018) 38 (1): BSR20170681.
Published: 05 January 2018
...Shanyang He; Yunhe Zhao; Xiaoping Wang; Yalan Deng; Zhiyong Wan; Shuzhong Yao; Hongwei Shen Long non-coding RNA small nucleolar RNA host gene 20 (SNHG20) has been demonstrated to play crucial regulatory roles in many types of cancer. However, the biological function of long ncRNA (lncRNA) SNHG20...
Includes: Supplementary data
Articles
Biosci Rep (2015) 35 (5): e00262.
Published: 30 October 2015
... homoeostasis and lead to a healthy phenotype. Two classes of ncRNA (non-coding RNA), miRNA and lncRNA (long non-coding RNA), play crucial roles in gene regulation during tissue development and remodelling. In the present review, we summarize recent findings on regulatory role of distinct ncRNAs in brown/beige...