...Xiuqin Ni; Xing Li; Bing Hu; Li Wang To evaluate the role of m 6 A methylation of mRNAs and long non-coding RNAs (lncRNAs) in chronic allergic asthma. Transcriptome-wide N6-methyladenosine (m 6 A) changes in BALB/c mice were profiled using immunoprecipitated methylated RNAs with microarrays in lung...

...Zhaoyu Liu; Jitao Chen; La Hu; Ming Li; Min Liang; Jianan Chen; Hai Lin; Zicheng Zeng; Weida Yin; Zhijie Dong; Jinsheng Weng; Wenxia Yao; Gao Yi Background : Heat stroke (HS) is a physically dysfunctional illness caused by hyperthermia. Lung, as the important place for gas-exchange and heat...

...Tian-hao Liu; Chen-yang Zhang; Ahmad Ud Din; Ning Li; Qian Wang; Jing-ze Yu; Zhen-yuan Xu; Chen-xi Li; Xiao-mei Zhang; Jia-li Yuan; Li-guo Chen; Zhong-shan Yang The association between lung and intestine has already been reported, but the differences in community structures or functions between...

...Tao Qiu; Jiangqiao Zhou; Tianyu Wang; Zhongbao Chen; Xiaoxiong Ma; Long Zhang; Jilin Zou Acute lung injury (ALI) is an acute inflammatory disease. Leukocyte immunoglobulin-like receptor B4 (LILRB4) is an immunoreceptor tyrosine-based inhibitory motif (ITIM)-bearing inhibitory receptor...

... processes of synthesis and degradation of ECM components markedly controlled by the MMPs/TIMP imbalance. We previously showed an association of the differences in collagen deposition in the lungs of bleomycin-treated mice with a reduced molar pro-MMP-9/TIMP-1 ratio. Using the carbon tetrachloride (CCl 4...

...Carolyn Lowe; Peter M. Barling; Stephen J. M. Skinner Parathyroid hormone (PTH, <10 −8 M) stimulated adenylate cyclase in fibroblasts, but not epithelial cells, isolated from fetal rat lung. In contrast to osteosarcoma cells (UMR 106), the response of fibroblasts to PTH was increased...