... in NASH progression to fibrosis and HCC [ 33 ]. Histology shows that B- and T-lymphocytes are present in either lobular or periportal infiltrates [ 34 ] often forming focal aggregates, resembling ectopic lymphoid structures [ 35 ]. Hepatic infiltration by B- and T-lymphocytes is also evident in different...

... lymphocytes apoptosis would have important implications. The present results indicate that ouabain, a specific inhibitor of Na + K + -ATPase, promotes an increased expression of c- myc mRNA, and induces apoptosis in PHA-stimulated lymphocytes. Furthermore, this ouabain-induced apoptosis cannot be counteracted...

... for Ca 2+ (K 0.5 > 1μM) observed upon expression in the COS cell system occurs also in its normal cellular context. SERCA3 is particularly expressed at high levels in different types of blood cells and related cells like platelets, lymphocytes, mast cells and arterial endothelial cells. It is also...

...George I. Malinin; Francis J. Hornicek; Theodore I. Malinin Blastogenic and cytotoxic effects of hexavalent chromium were evaluated by direct, 2 and 20 min oxidation of lymphocytes by 10.0 to 0.0005 mM CrO 3 at 0°C. Oxidized cells exhibited concentration-dependent cytotoxicity and the inhibition...

...Tiziana Bellini; Diana Degani; Maurizio Matteuzzi; Franco Dallocchio Pre-treatment of human lymphocytes with 17 β -estradiol diminishes the increase in concentration of cytosolic free calcium after stimulation with phytohaemagglutinin. The effect is dependent on 17 β -estradiol concentration...

...Tiziana Bellini; Diana Degani; Maurizio Matteuzzi; Franco Dallocchio Myelin Basic Protein, one of the major membrane protein component of the central nervous system, was used to probe the molecular mechanism of cellular activation by phytohaemagglutinin. Pre-treatment of human lymphocytes...

...) with monospecific antibodies against phospholipase C (PLC) produced a dose-dependent inhibition (up to 100%) of PHA (10 μg/ml) or ConA (25 μg/ml) proliferative effects. Thus, the activation of membrane-bound PLC is a sine-qua-non condition for lectin-induced proliferation of T lymphocytes. The key-role of PLC...

.... 4 2 1987 © 1987 Plenum Publishing Corporation 1987 polyoma capsids electroporation DNA/protein transfection lymphocytes Bioseience Reports, Vol. 7, No. 2, 1987 Transfection of a DNA/Protein Complex into Nuclei of Mammalian Cells Using Polyoma Capsids and Electroporation Wolf...

...Heiko Ziervogel; Roland Glaser; Dieter Schadow; Stephan Heymann Electrorotation—the spin of cells in rotating high frequency electric fields—has been used to investigate properties of human peripheral blood lymphocytes. The rotation spectra of lymphocytes deviate from those of single shell spheres...