... of membrane protein assembly and function in signal transduction pathways that control multiple cellular responses. Different signal transduction pathways are simultaneously activated by VEGFR–VEGF complexes with membrane trafficking along the endosome–lysosome network further modulating signal output from...

...Sang Yoon Park; Xiaoli Guo The AP (adaptor protein) complexes are heterotetrameric protein complexes that mediate intracellular membrane trafficking along endocytic and secretory transport pathways. There are five different AP complexes: AP-1, AP-2 and AP-3 are clathrin-associated complexes...

...Jae-Joon Jung; Shivangi M. Inamdar; Ajit Tiwari; Amit Choudhury Intracellular membrane trafficking along endocytic and secretory transport pathways plays a critical role in diverse cellular functions including both developmental and pathological processes. Briefly, proteins and lipids destined...

...Li Lu; Qian Cai; Jin-Hua Tian; Zu-Hang Sheng Late endocytic membrane trafficking delivers target materials and newly synthesized hydrolases into lysosomes and is critical for maintaining an efficient degradation process and cellular homoeostasis. Although some features of late endosome–lysosome...

.... The underlying mechanism governed by Rab7 and its partners will also be discussed. 1 To whom correspondence should be addressed (email [email protected] ). disease endocytosis membrane trafficking pathogen infection Rab7 virus Rab proteins are master regulators of membrane...

... that the trafficking of GLUT1, regulated by growth factors or oncogenes, may play an important role in the suppression of apoptosis in haemopoietic cells. 8 9 1995 © 1995 Plenum Publishing Corporation 1995 Transport glucose membrane trafficking interleukin-3 Abelson tyrosine kinase Bioscience...