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Keywords: microRNA
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Articles
Journal:
Bioscience Reports
Biosci Rep (2024) 44 (11): BSR-2018-0668_RET.
Published: 06 November 2024
... © 2024 The Author(s). 2024 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . biomarker cervical cancer MCM5 microRNA miR-362-3p This article “MiR...
Articles
Ashish Sarkar, Mohd Saquib, Debolina Chakraborty, Sonia Mann, Swati Malik, Prachi Agnihotri, Lovely Joshi, Rajesh Malhotra, Sagarika Biswas
Journal:
Bioscience Reports
Biosci Rep (2024) 44 (9): BSR20240311.
Published: 10 September 2024
...Ashish Sarkar; Mohd Saquib; Debolina Chakraborty; Sonia Mann; Swati Malik; Prachi Agnihotri; Lovely Joshi; Rajesh Malhotra; Sagarika Biswas Plant microRNAs (miRNA) are regularly consumed orally along with diet, gaining attention for their RNA-based drug potential because of their ability...
Includes: Supplementary data
Articles
Xinyu Wang, Tingting Zhang, Jianlong Zhai, Zhongli Wang, Yan Wang, Lili He, Sai Ma, Hanying Xing, Yifang Guo
Journal:
Bioscience Reports
Biosci Rep (2023) 43 (9): BSR20230014.
Published: 05 September 2023
...Xinyu Wang; Tingting Zhang; Jianlong Zhai; Zhongli Wang; Yan Wang; Lili He; Sai Ma; Hanying Xing; Yifang Guo MicroRNA-21 (miR‐21) plays an anti-apoptotic role following ischemia–reperfusion (I/R) injury (IRI) in vivo ; however, its underlying mechanism remains unclear. The present study explored...
Includes: Supplementary data
Articles
Journal:
Bioscience Reports
Biosci Rep (2022) 42 (7): BSR20212355.
Published: 15 July 2022
...). 2022 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . atherosclerosis endothelial cells microRNA non-coding RNA vascular smooth muscle Cardiovascular...
Articles
Journal:
Bioscience Reports
Biosci Rep (2022) 42 (1): BSR20211972.
Published: 11 January 2022
... and array technology. For domain 5 ‘Adjustment for covariates’, the core set of desired adjustment covariates was predefined as Gleason score/grade and pathological/clinical stage. meta analysis microRNA miR-21 prognostic prostate cancer systematic Prostate cancer (PCa) is the most...
Includes: Supplementary data
Articles
Journal:
Bioscience Reports
Biosci Rep (2021) 41 (12): BSR20211420.
Published: 08 December 2021
... of the present study was to apply bioinformatics analysis to explore tumor-educated platelet (TEP) microRNA (miRNA) expression and its potential diagnostic utility in HCC. Methods: Twenty-five HCC patients and 25 healthy controls were included. RNA sequencing was utilized to screen miRNA alterations in platelets...
Includes: Supplementary data
Articles
Journal:
Bioscience Reports
Biosci Rep (2021) 41 (10): BSR20211123.
Published: 19 October 2021
...Ying Jing; Donghai Li MicroRNAs (miRNAs) play important roles in a variety of human diseases, including breast cancer. A number of miRNAs are up- and down-regulated in breast cancer. However, little is known about miRNA similarity and similarity network in breast cancer. Here, a collection of 272...
Includes: Supplementary data
Articles
Nahla O. Mousa, Ahmed A. Sayed, Nagia Fahmy, Mariam G. Elzayat, Usama Bakry, Ahmed Abdellatif, Waheed K. Zahra, Ahmed Osman
Journal:
Bioscience Reports
Biosci Rep (2021) 41 (9): BSR20211325.
Published: 17 September 2021
... study, we sequenced the whole miRNome in leukocytes and plasma of the family members and results were validated using real-time PCR. Our results highlighted the role of miR-409-3p, miR-424-5p, miR-144-3p as microRNAs that show correlation with the extent of severity of muscular weakness and can be used...
Includes: Supplementary data
Articles
Isabel Witvrouwen, Dominique Mannaerts, Jessica Ratajczak, Evi Boeren, Ellen Faes, Amaryllis H. Van Craenenbroeck, Yves Jacquemyn, Emeline M. Van Craenenbroeck
Journal:
Bioscience Reports
Biosci Rep (2021) 41 (8): BSR20210874.
Published: 12 August 2021
... endothelial growth factor (VEGF) pathway is essential in the placentation process and VEGF expression is regulated through post-transcriptional modification by microRNAs (miRNAs). We investigated the expression of VEGF-related circulating miR-16, miR-29b, miR-126, miR-155 and miR-200c in PE vs healthy...
Articles
Journal:
Bioscience Reports
Biosci Rep (2021) 41 (7): BSR20210126.
Published: 01 July 2021
... the function of endothelial cells by dictating their microRNA (miRNA) expression remains largely unknown. Differentially expressed miRNAs (DEMs) were identified through dataset downloaded from the Gene Expression Omnibus (GEO) database and analyzed by GEO2R. We then used online tools to obtain potential...
Includes: Supplementary data
Articles
Journal:
Bioscience Reports
Biosci Rep (2021) 41 (2): BSR20201158.
Published: 17 February 2021
...Hao Qiu; Zhiqiang Xie; Weifeng Tang; Chao Liu; Yafeng Wang; Haiyong Gu; Qingfeng Zheng MicroRNA ( miR ) acts as a negative regulator of gene expression. Many literatures have suggested that miRs may be involved in the process of cell proliferation, inflammation, oxidative stress, energy metabolism...
Includes: Supplementary data
Articles
Journal:
Bioscience Reports
Biosci Rep (2021) 41 (1): BSR20203559.
Published: 07 January 2021
...Mengqiu Xiong; Ping Wang; Bei Pan; Junjie Nie; Shukui Wang; Bangshun He MicroRNA-196a (miR-196a) was previously reported to be up-regulated in cancers, and it has the diagnostic and prognostic values in cancers. Whereas, the conclusion was still unclear according to the published data. To assess...
Includes: Supplementary data
Articles
Journal:
Bioscience Reports
Biosci Rep (2020) 40 (11): BSR20201820.
Published: 17 November 2020
...Bo Ma; Hui Li; Jia Qiao; Tao Meng; Riyue Yu Background: Head and neck squamous cell carcinoma (HNSCC) is recognised as an immune active cancer, but little is known about the role of microRNAs (miRNAs) in it. In the present study, we aim to determine a prognostic and immune-related miRNAs signature...
Includes: Supplementary data
Articles
Hung-Ju Lin, Sung-Liang Yu, Ta-Chen Su, Hsiu-Ching Hsu, Ming-Fong Chen, Yuan-Teh Lee, Kuo-Liong Chien, Tzu-Pin Lu
Journal:
Bioscience Reports
Biosci Rep (2020) 40 (9): BSR20201885.
Published: 21 September 2020
... be a biomarker suboptimal to assess inflammation status. Although it has been reported that statins modulated inflammation via microRNAs (miRNAs), evidence remains lacking on comprehensive profiling of statin-induced miRNAome alterations in immune cells. We recruited 19 hypercholesterolemic patients receiving 2...
Includes: Supplementary data
Articles
Journal:
Bioscience Reports
Biosci Rep (2020) 40 (9): BSR20193974.
Published: 18 September 2020
...Peng Lv; Zhenzhu Zhang; Li Hou; Yayue Zhang; Lingeng Lu; Chong Wang; Fengqin Shi Low expression of tumor suppressor microRNA (miRNA) and high expression of carcinogenic miRNA promote the occurrence and progression of human cancer. Most studies show that miR-145 is a tumor suppressor miRNA...
Articles
Journal:
Bioscience Reports
Biosci Rep (2020) 40 (5): BSR20191028.
Published: 07 May 2020
...Daniel Lee; Wei Tang; Tiffany H. Dorsey; Stefan Ambs BACKGROUND: microRNAs (miRs) regulate the expression of protein-coding genes and play key roles in various biological processes, including development and immunity. However, dysregulation of miR expression is also involved in disease biology...
Includes: Supplementary data
Articles
Journal:
Bioscience Reports
Biosci Rep (2020) 40 (4): BSR20182458.
Published: 21 April 2020
...Tingting Jia; Yipeng Ren; Fengze Wang; Rui Zhao; Bo Qiao; Lejun Xing; Long Ou; Bin Guo Objective: The current study aimed to investigate the functional roles and clinical significance of microRNA-148a ( miR-148a ) in the progression of oral squamous cell carcinoma (OSCC). Methods: Relative...
Includes: Supplementary data
Articles
Journal:
Bioscience Reports
Biosci Rep (2020) 40 (1): BSR20190303.
Published: 17 January 2020
...Ying Xin; Xueqiang Wang; Kexin Meng; Chao Ni; Zhenye Lv; Dandan Guan Accumulated evidence has demonstrated exosomes of cancer cells carry microRNAs (miRNAs) to non-malignant cells to induce metastasis. The present study aimed to identify crucial exosomal miRNAs for breast cancer (BC) using...
Articles
Journal:
Bioscience Reports
Biosci Rep (2020) 40 (1): BSR20191234.
Published: 10 January 2020
...Derong Huang; Zhongxiu Chen; Jie Wang; Yucheng Chen; Daxing Liu; Ke Lin Aim: Circulating microRNA expression has become a biomarker of cardiovascular disease; however, the association of microRNA expression between circulation and myocardium in hypertrophic cardiomyopathy remains unclear...
Includes: Supplementary data
Articles
George S. Krasnov, Grigory A. Puzanov, Marina A. Afanasyeva, Erdem B. Dashinimaev, Khava S. Vishnyakova, Artemy D. Beniaminov, Alexei A. Adzhubei, Tatiana T. Kondratieva, Yegor E. Yegorov, Vera N. Senchenko
Journal:
Bioscience Reports
Biosci Rep (2019) 39 (12): BSR20193094.
Published: 13 December 2019
... This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . cell cycle microRNA SCP/CTDSP phosphatases tumor suppressors Lung cancer is the most commonly diagnosed cancer...
Includes: Supplementary data
Articles
Journal:
Bioscience Reports
Biosci Rep (2019) 39 (12): BSR20181404.
Published: 13 December 2019
... of microRNAs (miRNAs) play an important role in developing the disease which can be considered as early stage biomarkers. Since, selective, sensitive, simple and rapid method for detection of these miRNAs in a single test is critical for early diagnosis and efficient therapy of the disease, herein, we report...
Articles
Overcoming cisplatin resistance in osteosarcoma through the miR-199a -modulated inhibition of HIF-1α
Ajimu Keremu, Abudureyimu Aini, Yusufuaji Maimaitirexiati, Zhilin Liang, Pazila Aila, Paizila Xierela, Aikebaier Tusun, Hanikezi Moming, Aihemaitijiang Yusufu
Journal:
Bioscience Reports
Biosci Rep (2019) 39 (11): BSR20170080.
Published: 15 November 2019
... and controls was assessed by Student’s t test. The difference was considered significant with the P- value was less than 0.05. Correspondence: Aihemaitijiang Yusufu ( [email protected] ) cisplatin sensitivity HIF-1α microRNA miR-199a osteosarcoma miRNAs are a class of small...
Articles
Journal:
Bioscience Reports
Biosci Rep (2019) 39 (7): BSR20190955.
Published: 23 July 2019
... microRNA tongue squamous cell carcinoma SP1 STAT3 Tongue squamous cell carcinoma (TSCC) is the most common oral cancer; its incidence is about one-third to half of that of all oral cancers [ 1 ]. The pathogenesis of TSCC is related to many factors, including anatomical location, race, age...
Articles
LncRNA PFAR contributes to fibrogenesis in lung fibroblasts through competitively binding to miR-15a
Jian Sun, Wei Su, Xiaoguang Zhao, Tianjiao Shan, Tongzhu Jin, Yingying Guo, Chao Li, Ruotong Li, Yuhong Zhou, Hongli Shan, Xiaohan Sun, Haihai Liang
Journal:
Bioscience Reports
Biosci Rep (2019) 39 (7): BSR20190280.
Published: 19 July 2019
... of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . fibroblasts large intervening non-coding RNA microRNA Idiopathic pulmonary fibrosis (IPF), the most common idiopathic interstitial pneumonia, is characterized by cell proliferation, interstitial...
Articles
Journal:
Bioscience Reports
Biosci Rep (2019) 39 (7): BSR20190298.
Published: 19 July 2019
...Yingqi Xiao; Hui Liu; Li Chen; Yang Wang; Xiang Yao; Xiaolian Jiang Objective: To investigate whether microRNAs genes’ polymorphisms are associated with arthritis. Methods: The PubMed, Cochrane Library et al. were systematically searched to identify case–control studies, systematic reviews and meta...
Includes: Supplementary data
Articles
Journal:
Bioscience Reports
Biosci Rep (2019) 39 (7): BSR20190996.
Published: 05 July 2019
....2018.08.152 30173892 15. Wong N. and Wang X. ( 2015 ) miRDB: an online resource for microRNA target prediction and functional annotations . Nucleic Acids Res. 43 , D146 – D152 10.1093/nar/gku1104 25378301 16. Fromm B. , Billipp T. , Peck L.E. et al...
Articles
Journal:
Bioscience Reports
Biosci Rep (2019) 39 (7): BSR20180695.
Published: 02 July 2019
...Siwen Tang; Hongyu Fu; Qihua Xu; Ying Zhou Colorectal cancer (CRC) is one of the leading cancer-related causes of deaths in the world. Recently, microRNAs have been reported to regulate the tumor growth, invasion and the immunosuppression. In the present study, we found that miR-20a was increased...
Articles
Journal:
Bioscience Reports
Biosci Rep (2019) 39 (5): BSR20182232.
Published: 14 May 2019
... License 4.0 (CC BY) . Arginine vasopressin receptor 1a hypertension microRNA single nucleotide polymorphism Essential hypertension is a common cardiovascular disease in middle-aged and elderly populations. Its clinical characteristics are elevated blood pressure and multiple...
Articles
Journal:
Bioscience Reports
Biosci Rep (2019) 39 (5): BSR20182485.
Published: 02 May 2019
... (UTR) of APP are associated with the development of AD. Since microRNAs (miRNAs) are involved in the regulation of APP expression, we believe that the APP 3′UTR polymorphism may affect the regulation of APP expression in miRNAs. Results : The levels of miR-101-3p, miR-153-3p, miR-144-3p, miR-381-3p...
Articles
Journal:
Bioscience Reports
Biosci Rep (2019) 39 (4): BSR20180723.
Published: 16 April 2019
... in microRNAs (miRNAs/miRs) play an important role in the susceptibility of various types of cancers. Objective: To evaluate the association of Single Nucleotide Polymorphisms (SNPs) in miR-146a (rs2910164), miR-196a2 (rs11614913), and miR-499 (rs3746444), with cervical cancer susceptibility in Indian...
Includes: Supplementary data
Articles
Carlos Zaragoza, Marta Saura, Ignacio Hernández, Rafael Ramirez-Carracedo, Francisco García-García, Jose L. Zamorano, Alipio Mangas, Rocio Toro
Journal:
Bioscience Reports
Biosci Rep (2019) 39 (3): BSR20180934.
Published: 15 March 2019
...Carlos Zaragoza; Marta Saura; Ignacio Hernández; Rafael Ramirez-Carracedo; Francisco García-García; Jose L. Zamorano; Alipio Mangas; Rocio Toro A new familial dilated cardiomyopathy (FDCM) was found related to mutations in BAG3 gene. MicroRNAs (miRNAs) represent new targets of FDCM, although...
Articles
Journal:
Bioscience Reports
Biosci Rep (2019) 39 (1): BSR20180395.
Published: 03 January 2019
... microRNA Migration Proliferation Glioma, as a very common malignant tumor in the human central nervous system, features rapid growth, strong invasion, high mortality and high disability rates, accounting for approximately 60% of adult primary brain tumors [ 1 , 2 ]. Although great advances have...
Articles
Journal:
Bioscience Reports
Biosci Rep (2018) 38 (6): BSR20181386.
Published: 14 December 2018
... © 2018 The Author(s). 2018 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . colorectal cancer large intervening non-coding RNA microRNA tumorigenesis...
Articles
Kyoung Hwa Lee, Beom Jin Lim, Victor H. Ferreira, Seo Yeon Min, Yeon-Mi Hong, Jeong-Hyeon Jo, Sang Hoon Han
Journal:
Bioscience Reports
Biosci Rep (2018) 38 (6): BSR20180961.
Published: 07 December 2018
... as 0.996 for hsa-miR-200b-3p, 0.994 for -200c-3p, 0.987 for HCMV, and 0.959 for GAPDH. cytomegalovirus immediate early protein 2 microRNA tissues Human cytomegalovirus (HCMV) replication can cause serious harm in solid organ transplantation (SOT) and hematopoietic stem cell transplantation...
Articles
Yanli Wang, Ke Lv, Hailong Chen, Mei Zhao, Guohua Ji, Yongliang Zhang, Hongqing Cao, Guanghan Kan, Yinghui Li, Lina Qu
Journal:
Bioscience Reports
Biosci Rep (2018) 38 (6): BSR20180233.
Published: 07 December 2018
... 2.048 mmu-miR-199b* 2 miR-199 0.948 mmu-miR-429 4 miR-8 1.937 mmu-miR-203 12 miR-203 3.502 mmu-let-7a* 13 Let-7 1.950 mmu-miR-375 1 miR-375 3.760 mmu-let-7f* 13 Let-7 1.595 mmu-miR-449a 13 miR-449 1.244 Circadian rhythms Clock mutation microRNA...
Articles
Bin Sheng, Nian-sheng Lai, Yang Yao, Jin Dong, Zhen-bao Li, Xin-tong Zhao, Jia-qiang Liu, Xue-qin Li, Xing-gen Fang
Journal:
Bioscience Reports
Biosci Rep (2018) 38 (6): BSR20180646.
Published: 21 November 2018
... , 9 ]. In addition, we need a reliable, early, cost-effective, and non-invasive approach to screen patients in order to improve prognosis in aSAH. MicroRNAs (miRNAs) are an abundant class of highly conserved non-coding RNA molecules, consisting approximately 22 nts. They play key roles...
Articles
Journal:
Bioscience Reports
Biosci Rep (2018) 38 (6): BSR20181090.
Published: 16 November 2018
... of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . Breast cancer Chemoresistance Exosomes MicroRNA Breast cancer is the most common malignant tumor resulting in high mortality amongst females worldwide [ 1 ]. Although chemotherapy plays...
Articles
Journal:
Bioscience Reports
Biosci Rep (2018) 38 (6): BSR20181578.
Published: 14 November 2018
... tubule is a direct target of injury in IgAN [ 5 ]. Hence, proteinuria in IgAN may reflect both glomerular damage as well as proximal tubule injury leading to increased glomerular filtration and decreased tubular reabsorption, respectively. cell transfection IgA nephropathy megalin microRNA...
Articles
Journal:
Bioscience Reports
Biosci Rep (2018) 38 (5): BSR20180516.
Published: 23 October 2018
... the Creative Commons Attribution License 4.0 (CC BY) . autophagy large intervening non-coding RNA microRNA oncogenesis gene therapy Autophagy is a process of sustaining metabolism and homeostasis by capturing and degrading intracellular components such as proteins and organelles. Autophagy...
Articles
Journal:
Bioscience Reports
Biosci Rep (2018) 38 (5): BSR20180915.
Published: 10 October 2018
... BY) . chemoresistance drug resistance hepatocellular carcinoma HCC long non-coding RNA microRNA Hepatocellular carcinoma (HCC) is one of the most frequently diagnosed cancers and the second leading cause of cancer-related deaths amongst males worldwide, which is largely caused by chronic hepatitis B virus...
Articles
Journal:
Bioscience Reports
Biosci Rep (2018) 38 (4): BSR20180448.
Published: 03 July 2018
... BY) . Bone remodeling compression fluid shear stress mechanical cyclical stretch microgravity microRNA Compressive force plays an important role in osteoclastogenesis. Both compressive force and hypoxia may initiate osteoclastogenesis during OTM [ 28 ]. Heavy compression causes bone fracture...
Articles
Journal:
Bioscience Reports
Biosci Rep (2018) 38 (3): BSR20180668.
Published: 21 June 2018
... histological grade, and poor prognosis. Down-regulation of MCM5 inhibited cervical adenocarcinoma cell proliferation. The purpose of the present study is to search and confirm valuable microRNAs (miRNAs), which target MCM5 to modulate cervical adenocarcinoma cell proliferation. In our results, we found...
Articles
Journal:
Bioscience Reports
Biosci Rep (2018) 38 (3): BSR20180453.
Published: 21 June 2018
... be the underlying mechanisms that link genetic and environmental factors with increased risks of osteoporosis and bone fracture. MicroRNA (miRNA), a major category of small noncoding RNA with 20–22 bases in length, is recognized as one important epigenetic modification. It can mediate post-transcriptional...
Articles
Journal:
Bioscience Reports
Biosci Rep (2018) 38 (2): BSR20171208.
Published: 21 March 2018
... in vascular endothelial injury. It is an important factor in the development of diabetes mellitus (DM). The aim of the present study was to screen out the potential candidate microRNAs (miRNAs) in DM patients with BSS by high-throughput sequencing (HTS) and bioinformatics analysis. Human umbilical vein...
Articles
Jin-yan Wang, Qian Zhang, Dan-dan Wang, Wei Yan, Huan-huan Sha, Jian-hua Zhao, Su-jin Yang, He-da Zhang, Jun-chen Hou, Han-zi Xu, Yun-jie He, Jia-hua Hu, Shan-liang Zhong, Jin-hai Tang
Journal:
Bioscience Reports
Biosci Rep (2018) 38 (1): BSR20171265.
Published: 08 February 2018
...(s). 2018 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . biomarkers cancer metastases microRNA miR-29a proliferation An increasing number...
Articles
Journal:
Bioscience Reports
Biosci Rep (2017) 37 (6): BSR20171157.
Published: 29 November 2017
... vascular permeability, and retinal NV. diabetic retinopathy dysregulation long noncoding RNA molecular mechanisms microRNA Mortuza et al. [ 61 ] demonstrated that up-regulation of miR-195 in HRECs exposed to HG and in the retinas of diabetic rats is accompanied by a concomitant down...
Articles
Ming Xu, Zhengmin Yu, Feifei Hu, Hongbing Zhang, Lixin Zhong, Lei Han, Yan An, Baoli Zhu, Hengdong Zhang
Journal:
Bioscience Reports
Biosci Rep (2017) 37 (5): BSR20171111.
Published: 31 October 2017
... chronic lead exposure diagnosis microRNA Lead (Pb) is a common material existing in the Earth, and widely utilized in industry. The most important artificial sources for lead emission are considered to be mining and metal smelting [ 1 , 2 ]. As a classical environmental and occupational toxicant...
Articles
Journal:
Bioscience Reports
Biosci Rep (2017) 37 (5): BSR20170768.
Published: 11 October 2017
... The Author(s). 2017 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . microRNA miRNA sequence analysis osteoclasts peri-implantitis Over the past decade...
Includes: Supplementary data
Articles
Journal:
Bioscience Reports
Biosci Rep (2017) 37 (4): BSR20170149.
Published: 31 August 2017
..., increased the expression of miR-98 and suppressed the expression of TSP1 in peripheral B cells, which was abolished by knocking down the miR-98 gene. In conclusion, miR-98 can suppress the expression of TSP1 in the peripheral B cells of patients with allergic asthma. B lymphocyte IL-10 microRNA...
Articles
Journal:
Bioscience Reports
Biosci Rep (2017) 37 (3): BSR20160404.
Published: 07 June 2017
... Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . hexokinase 2 microRNA miR-143 oral cancer Oral squamous cell carcinoma (OSCC) is the most common head and neck neoplasm, representing 95% of all forms of head...
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