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Keywords: mitochondrial metabolic adaption
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Journal:
Bioscience Reports
Biosci Rep (2020) 40 (1): BSR20192465.
Published: 17 January 2020
... the detoxification and the mitochondrial metabolic adaption in breast cancer resistant to lapatinib; ERRα activates SHMT2 transcription via targeting its promoter region, therefore enhancing breast cancer resistance to lapatinib. Herein, ERRα and SHMT2 expression and protein levels could be determined in parental...