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Keywords: mitogen-activated protein kinase (MAPK)
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Articles

TAK-242, a small-molecule inhibitor of Toll-like receptor 4 signalling, unveils similarities and differences in lipopolysaccharide- and lipidinduced inflammation and insulin resistance in muscle cells

Open Access
Sophie E. Hussey, Hanyu Liang, Sheila R. Costford, Amira Klip, Ralph A. DeFronzo, Alicia Sanchez-Avila, Brian Ely, Nicolas Musi
Journal: Bioscience Reports
Biosci Rep (2013) 33 (1): e00004.
https://doi.org/10.1042/BSR20120098
Published: 30 November 2012
... protein kinase (MAPK) nuclear factor κB (NF-κB) saturated non-esterified fatty acid (NEFA) Toll-like receptor 4 (TLR4). Insulin resistance is a characteristic feature of obesity and Type 2 diabetes mellitus. Skeletal muscle is the main site responsible for insulin-stimulated glucose disposal...
View articletitled, TAK-242, a small-molecule inhibitor of Toll-like receptor 4 signalling, unveils similarities and differences in lipopolysaccharide- and lipidinduced inflammation and insulin resistance in muscle cells
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Includes: Supplementary data
Articles

Tumour necrosis factor receptor trafficking dysfunction opens the TRAPS door to pro-inflammatory cytokine secretion

Open Access
Mark D. Turner, Anupama Chaudhry, Belinda Nedjai
Journal: Bioscience Reports
Biosci Rep (2012) 32 (2): 105–112.
https://doi.org/10.1042/BSR20110089
Published: 31 October 2011
... the terms of the Creative Commons Attribution Non-Commercial Licence ( http://creativecommons.org/licenses/by-nc/2.5/ ) which permits unrestricted non-commercial use, distribution and reproduction in any medium, provided the original work is properly cited. mitogen-activated protein kinase (MAPK...
View articletitled, Tumour necrosis factor receptor trafficking dysfunction opens the TRAPS door to pro-inflammatory cytokine secretion
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