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Keywords: mitogen-activated protein kinases
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Articles
Tian Hu, Yan Zhao, Yan Long, Xiaoqing Ma, Ya Zeng, Weijie Wu, Chongtian Deng, Mengling Li, Siyuan Peng, Hanzhi Yang, Mi Zhou, Jinyue Hu, Yueming Shen
Journal:
Bioscience Reports
Biosci Rep (2022) 42 (4): BSR20220307.
Published: 21 April 2022
... access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . inflammatory bowel disease mitogen-activated protein kinases tlr4 Inflammatory bowel disease (IBD) is a chronic...
Articles
Shikonin inhibits proliferation of melanoma cells by MAPK pathway-mediated induction of apoptosis
Open AccessJae Han Lee, So Hee Han, You Min Kim, Sung Hyun Kim, Eun Seon Yoo, Joong Seok Woo, Gi Hwan Jung, Soo Hyun Jung, Bum Seok Kim, Ji Youn Jung
Journal:
Bioscience Reports
Biosci Rep (2021) 41 (1): BSR20203834.
Published: 22 January 2021
... bromide) assay, 4′,6-diamidino-2-phenylindole (DAPI) stain, annexin V/ propidium iodide (PI) stain, and protein analysis of apoptosis and mitogen-activated protein kinase (MAPK) pathways). Further, the anticancer effect in vivo was confirmed through a xenograft model. Our results showed that shikonin...
Articles
Hypoxia potentiates monocyte-derived dendritic cells for release of tumor necrosis factor α via MAP3K8
Open AccessLaurent M. Paardekooper, Maura B. Bendix, Andrea Ottria, Lieke W. de Haer, Martin ter Beest, Timothy R.D.J. Radstake, Wioleta Marut, Geert van den Bogaart
Journal:
Bioscience Reports
Biosci Rep (2018) 38 (6): BSR20182019.
Published: 14 December 2018
... anti-cancer immunity and autoimmune disease. We show in human monocyte-derived DCs (moDCs) that this potentiation is controlled exclusively via the p38/mitogen-activated protein kinase (MAPK) pathway. We identified MAPK kinase kinase 8 (MAP3K8) as a target gene of hypoxia-induced factor (HIF...
Includes: Supplementary data
Articles
Journal:
Bioscience Reports
Biosci Rep (2013) 33 (3): e00041.
Published: 05 June 2013
...′-GGGCATGGGTCAGAAGGATT-3′ reverse: 5′-GAGGCGTACAGGGATAGCAC-3′ and (3) MMP-1 , forward: 5′-AGCTAGCTCAGGATGACATTGATG-3′ reverse: 5′-TCAGAAAGAGCAGCATCGATATG-3′. collagen cytochrome P450 2E1 diethyldithiocarbamate matrix metalloproteinase-1 mitogen-activated protein kinases reactive oxygen species DDC...