...Daqiu Chen; Yanqing Wu; Yixing Chen; Qiaoxing Chen; Xianhua Ye; Shanghua Xu; Shunxiang Luo Background: Suxiao Xintong dropping pills (SXXTDP), a traditional Chinese medicine, is widely applied for treating myocardial infarction (MI). However, its therapy mechanisms are still unclear. Therefore...

... ischemia myocardial infarction (MI) through ligation of the left anterior descending (LAD) artery in Sprague–Dawley (SD) rats. Endostatin level in serum was increased in MI rats. The decrease in cardiac function and hemodynamics in MI rats were enhanced by endostatin overexpression. Endostatin...

... with ST segment elevation myocardial infarction (STEMI) may present large myocardial necrosis and significant impairment of ventricular function. The present study aimed to evaluate the role of subtypes of B lymphocytes and related cytokines in the infarcted mass and left ventricular ejection fraction...

...Shan Tang; Hongyan Zhong; Ting Xiong; Xinquan Yang; Yongqing Mao; Daxin Wang Myocardial infarction (MI) is a major type of cardiovascular disorder worldwide. In the present study, we established a new microRNA (miRNA)–mRNA cross-talk network by integrating data obtained from The National Center...

...Shao-Yan Zhang; Chao Xuan; Yi Wang; Shao-Qiang Zhang; Hui Li; Guo-Wei He; Qing-Wu Tian Background: Genome-wide linkage analysis revealed the polymorphism of rs6748040 and glutamic acid repeat are potential pathogenic factors of early-onset myocardial infarction (MI). The present study was designed...

...Nada J. Habeichi; Ali Mroueh; Abdullah Kaplan; Rana Ghali; Hiam Al-Awassi; Cynthia Tannous; Ahmad Husari; Abdo Jurjus; Raffaele Altara; George W. Booz; Ahmed El-Yazbi; Fouad A. Zouein The impact of cigarette smoking (CS) on kidney homeostasis in the presence of myocardial infarction (MI) in both...

...Junjie He; Ying Lu; Xiaozheng Song; Xiaoxuan Gong; Yong Li The aim of the present study was to determine the roles of microRNA (miR)-146a on myocardial infarction (MI)-induced heart failure and cardiac remodeling. Experiments were carried out in Sprague-Dawley rats treated with ligation of left...

...Xiaohong Gong; Yun Zhu; Haixia Chang; Yongqin Li; Feng Ma Our study aims to excavate the role of metastasis-associated lung adenocarcinoma transcript 1 (MALAT1) in myocardial infarction (MI), especially in an ischemia/reperfusion injury model and the underlying mechanism involving the MALAT1-miR144...

...Lili Wu; Guofan Chen; Jia Song Transforming growth factor (TGF)-β1 contributed to angiotensin II (Ang II)-mediated collagen accumulation after myocardial infarction (MI). The present study aimed to investigate the association of genetic variant of TGF-β1 gene with the risk of MI. The present study...

...Yao Hu; Yu Tao; Jing Hu Cannabinoid receptor 2 (CB2R) has been reported to play an important role in the regulation of pathogenesis and progression of myocardial infarction (MI). Here we tried to investigate its potential mechanisms. The ratio of infarct size in heart issue was detected by TTC...

... clinical heart failure can emerge several years following acute myocardial infarction (AMI), the impact of AMI on cerebral blood flow (CBF) at early stages and up to 30 days following MI is unknown. Sixteen months old male mice underwent left anterior descending (LAD) coronary artery ligation. Hemodynamics...

... that there are no competing interests associated with the manuscript. BMI body mass index CHD coronary heart disease CI confidence interval HDL high-density lipoprotein HWE Hardy–Weinberg equilibrium LDL low-density lipoprotein MI myocardial infarction OR odds ratios SNP...

... proteins in cardiomyocytes may therefore provide new insights into the mechanisms which link metabolic stress with cardiac disease following myocardial infarct. Correspondence: Samuel Boateng ( [email protected] ) and Olga Koroleva ( [email protected] ) * These authors...

... hypertrophy after myocardial infarction (MI). Male Wistar rats after induction of MI were randomized to either vehicle or lithium (1 mmol/kg per day) for 4 weeks. The dose of lithium led to a mean serum level of 0.39 mM, substantially lower than the therapeutic concentrations (0.8–1.2 mM). Infarction...

...Xuefeng Qu; Xiaotong Song; Wei Yuan; You Shu; Yuying Wang; Xuyun Zhao; Ming Gao; Renzhong Lu; Shenjian Luo; Wei Zhao; Yue Zhang; Lihua Sun; Yanjie Lu The present study aimed to investigate whether long non-coding RNAs (lncRNAs) are involved in cardiac fibrogenesis induced by myocardial infarction...

...Tsung-Ming Lee; Wei-Ting Chen; Nen-Chung Chang Myocardial infarction (MI) was associated with insulin resistance, in which resistin acts as a critical mediator. We aimed to determine whether sitagliptin, a dipeptidyl peptidase-4 (DPP-4) inhibitor, can attenuate arrhythmias by regulating resistin...

...Xianli Wang; Qian Wang; Wei Guo; Yi Zhun Zhu HF (heart failure) after MI (myocardial infarction) is a major cause of morbidity and mortality worldwide. Recent studies have shown that hydrogen sulfide (H 2 S) has cardioprotective effects. Hence, we aimed to elucidate the potential effects of H 2 S...