...-, 2-, and 3-year survival times, respectively). Significant differences were identified between the high and low immunoscore groups in overall survival and disease-free survival in training and validation cohorts. Combining the immunoscore with clinical information may provide a more accurate...

... and other signaling pathways. In the present study, we have identified that CAHM may serve as novel prognostic biomarkers for predicting overall survival (OS) in patients with THCA. Correspondence: Yong Xiao ( [email protected] ) or Yuantao Li ( [email protected] ) 30 01 2021 09 03...

... the relationship between the predictive lncRNAs and the overall survival of patients with BC. Besides, the risk scores were calculated using the equation below. In the present research, we downloaded significant RNA sequence profiles and relevant clinical data from The Cancer Genome Atlas (TCGA) database...

...Ke Xu; Jie He; Jie Zhang; Tao Liu; Fang Yang; Tao Ren Purpose: The aims of the present study were to explore immune-related genes (IRGs) in stage IV colorectal cancer (CRC) and construct a prognostic risk score model to predict patient overall survival (OS), providing a reference for individualized...

... stage, high frequency of positive lymph nodes, and worse 5-year overall survival. Conclusions: We found nine key genes were enriched in the cell cycle and p53 signaling pathway. TTK could be considered as a potential therapeutic target and for the prognosis biomarker of NSCLC. These findings...

... patients were recruited between 2010 and 2019 from the Fourth Hospital of Hebei Medical University. RT-PCR was used to measure the relative expression of CLCA4 and MS4A12. Furthermore, the study explored the effect of expression of CLCA4 and MS4A12 for overall survival. Results: A total of 53 DEGs were...

... (LNR), anemia and albumin, which were all assembled into the nomogram. The calibration curve verified excellent models’ concordance. The C-index of the nomogram was 0.73 (0.68–0.78), and the area under curve (AUC) of nomogram in predicting overall survival (OS) was 0.766, which were significantly...

.... Aberrant DNA methylation is frequently observed in the bladder cancer and holds considerable promise as a biomarker for predicting the overall survival (OS) of patients. Materials and methods: We downloaded the DNA methylation and transcriptome data for bladder cancer from The Cancer Genome Atlas (TCGA...

... =0.000). The Kaplan–Meier curve indicated the high TK1 group was poorer than that in the low TK1 group ( P =0.002). For the overall survival (OS), similar results were found that the high TK1 was related to poor OS (HR = 1.89, 95% CI: 1.34–3.67, P =0.000). The multivariate Cox regression indicated...

... was significantly higher in HCC tumors ( P = 4.28E-08). Additionally, E2F8 elevation significantly correlated with overall survival (OS), recurrence-free survival (RFS), disease-specific survival (DSS) and progression-free survival (PFS) in HCC patients (all P < 0.01). E2F8 level was significantly higher in HCC...

.... The DEmRNAs in the ceRNA network were found to be enriched in various cancer-related biological processes and pathways. We detected 22 lncRNAs, 12 mRNAs, and 1 miRNA in the ceRNA network that were significantly associated with the overall survival of patients with LUAD ( P < 0.05). We established three...

...Shaonan Fan; Ting Li; Ping Zhou; Qiliang Peng; Yaqun Zhu Purpose: Nomogram is a widely used tool that precisely predicts individualized cancer prognoses. We aimed to develop and validate a reliable nomogram including serum tumor biomarkers to predict individual overall survival (OS) for patients...

...Chaoran Yu; Yujie Zhang The present study was to develop a prognostic nomogram to predict overall survival (OS) and cancer-specific survival (CSS) in early-onset colon cancer (COCA, age < 50). Patients diagnosed as COCA between 2004 and 2015 were retrieved from the surveillance, epidemiology...

... was significantly associated with worse overall survival (OS) (Log rank P =0.00338, P =0.0447, P =0.00965, and P =0.00479, respectively), which was validated using a Kaplan–Meier plotter with a median cutoff (Log rank P =0.028, P =0.0035, P =0.039, and P =0.0033, respectively). Moreover, overexpression of BUB1B...

... remain in dispute. In the present study, we mined the ‘Kaplan–Meier plotter’ (KM plotter) online database to explore the prognostic roles of STAT family mRNA expression in breast cancer including overall survival (OS), progression-free survival (PFS), as well as post-progression survival (PPS...

.... Siglec gene expression between tumor and non-tumor tissues were compared and correlated with overall survival (OS) from HCC patients in GSE14520 microarray expression profile. Siglec-1 to siglec-9 were all down-regulated in tumor tissues compared with those in non-tumor tissues in HCC patients (all P...

... survival (DFS) and overall survival (OS) of breast cancer patients were investigated. Univariate and multivariate analyses were performed to explore factors influencing SLN metastasis and prognosis of breast cancer. Compared with adjacent tissues, HER-2 expression was significantly up-regulated in breast...