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Keywords: oxidative stress
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Articles
Journal:
Bioscience Reports
Biosci Rep (2024) 44 (12): BSR20240689.
Published: 12 December 2024
... that Rap1 is also involved in cell wall integrity, biofilm formation, and virulence in C. albicans . In this work, using RNA-seq analysis and other approaches, the role of C. albicans Rap1 in oxidative stress response was further revealed. The RAP1 -deletion mutant exhibited greater resistance...
Includes: Supplementary data
Articles
Aaron Barron, Jetro J. Tuulari, Linnea Karlsson, Hasse Karlsson, Gerard W. O'Keeffe, Cathal M. McCarthy
Journal:
Bioscience Reports
Biosci Rep (2024) 44 (11): BSR20240763.
Published: 21 November 2024
...Aaron Barron; Jetro J. Tuulari; Linnea Karlsson; Hasse Karlsson; Gerard W. O'Keeffe; Cathal M. McCarthy Early-onset pre-eclampsia is believed to arise from defective placentation in the first trimester, leading to placental ischaemia/reperfusion (I/R) and oxidative stress. However, our current...
Articles
Journal:
Bioscience Reports
Biosci Rep (2024) 44 (11): BSR20241102.
Published: 06 November 2024
... in the mRNA expression of COX-2 in brain tissues compared with lead-intoxicated rats without ZnO-NPs treatment. Finally, in the study by Hamza et al . [ 51 ], it was observed that monosodium glutamate-induced oxidative stress elevated COX-2 activity and prostaglandin E2 protein levels in the cerebral cortex...
Articles
Astrid Mayleth Rivera Antonio, Itzia Irene Padilla Martínez, Yazmín Karina Márquez-Flores, Alan Hipólito Juárez Solano, Mónica A. Torres Ramos, Martha Cecilia Rosales Hernández
Journal:
Bioscience Reports
Biosci Rep (2024) 44 (10): BSR20240797.
Published: 04 October 2024
..., damage to the epithelial barrier, a dysregulated immune response, and environmental factors [ 7 ]. It is microscopically characterized by severe inflammation due to inflammatory cell infiltration, proinflammatory cytokine production, T cells and oxidative stress, and macroscopically characterized...
Includes: Supplementary data
Articles
Journal:
Bioscience Reports
Biosci Rep (2024) 44 (8): BSR-2019-1711_RET.
Published: 22 August 2024
... © 2024 The Author(s). 2024 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . intervertebral disc nucleus pulposus osmolarity oxidative stress...
Articles
Journal:
Bioscience Reports
Biosci Rep (2024) 44 (6): BSR-2019-4347_EOC.
Published: 21 June 2024
... © 2024 The Author(s). 2024 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . Age‐related macular degeneration (AMD) madecassoside (MADE) oxidative...
Articles
Pengfei Tong, Jingke Zhang, Shuang Liu, Jiyang An, Gehan Jing, Laifeng Ma, Ruihua Wang, Zhengfeng Wang
Journal:
Bioscience Reports
Biosci Rep (2024) 44 (5): BSR20231511.
Published: 15 May 2024
..., respectively. Each RNA amplification was performed in triplicate, and the gene expression levels were calculated using the 2 −ΔΔCt calculated method. Experiments were independently conducted three times. endothelial cells miRNA-142-3p oxidative stress Senescence sirtuins stroke The Science...
Includes: Supplementary data
Articles
Barakat M. ALRashdi, Roaya A. Mohamed, Amal H. Mohamed, Feryal A. Samoul, Mazen I. Mohamed, Mohsen M. Moussa, Saad M. Alrashidi, Bassel Dawod, Ola A. Habotta, Ahmed E. Abdel Moneim, Shimaa S. Ramadan
Journal:
Bioscience Reports
Biosci Rep (2023) 43 (11): BSR20231130.
Published: 10 November 2023
...-acetyl cysteine (NAC) on the levels of non-enzymatic oxidative stress markers [(A) MDA, (B) NO, and (C) GSH] in the kidney of cisplatin (CDDP)-injected mice Data are expressed as mean ± SD ( n =7). a and b denote significant differences ( P <0.05) compared with the untreated control and CDDP-treated...
Articles
Mohit Arora, Sarita Kumari, Lokesh Kadian, Geethadevi Anupa, Jay Singh, Anurag Kumar, Deepika Verma, Raja Pramanik, Sunil Kumar, Rajni Yadav, Anita Chopra, Shyam S. Chauhan
Journal:
Bioscience Reports
Biosci Rep (2023) 43 (9): BSR20222472.
Published: 06 September 2023
..., increased apoptosis, and inhibited migration of ESCC cells. Additionally, DPP3 knockdown leads to down-regulation of the NRF2 pathway proteins, such as NRF2, G6PD, and NQO1 along with increased sensitivity toward oxidative stress-induced cell death and chemotherapy. Conclusively, these results demonstrate...
Includes: Supplementary data
Articles
Louise C. Kenny, on behalf of the SCOPE Consortium, Leslie W. Brown, Paloma Ortea, Robin Tuytten, Douglas B. Kell
Journal:
Bioscience Reports
Biosci Rep (2023) 43 (7): BSR20230160.
Published: 06 July 2023
... for this article was enabled by the participation of University of Liverpool in an all-inclusive Read & Publish agreement with Portland Press and the Biochemical Society under a transformative agreement with JISC. Ergothioneine Metabolomics Oxidative stress Preeclampsia Pre-eclampsia (PE...
Includes: Supplementary data
Articles
Mostafa Morad, Taha F. Hassanein, Manal F. El-khadragy, Alaa Fehaid, Ola A. Habotta, Ahmed Abdel Moneim
Journal:
Bioscience Reports
Biosci Rep (2023) 43 (5): BSR20222308.
Published: 18 May 2023
... with 100 and 1000 µg Cu L −1 of copper oxide nanoparticles (CuONPs) or ionic copper (Cu 2+ ) for 3, 7, and 14 days. The Cu accumulation and markers of oxidative stress in the digestive glands and gills were evaluated. The results show that the digestive gland collected higher levels of the two forms...
Articles
Journal:
Bioscience Reports
Biosci Rep (2022) 42 (9): BSR20221306.
Published: 02 September 2022
..., and the infarct size (IS) was assessed by Evan’s blue and 2,3,5-triphenyltetrazolium chloride (TTC) staining. Oxidative stress was assessed through Western blotting for expression of Keap1-Nrf2/ARE pathway members and oxidative stress markers. Results: Cardioprotection of DEX, tBHQ, and tBHQ+DEX preconditioning...
Articles
Tao Wang, Fei Zhang, Wuxun Peng, Lei Wang, Jian Zhang, Wentao Dong, Xiaobin Tian, Chuan Ye, Yanlin Li, Yuekun Gong
Journal:
Bioscience Reports
Biosci Rep (2022) 42 (1): BSR20211005.
Published: 14 January 2022
...Tao Wang; Fei Zhang; Wuxun Peng; Lei Wang; Jian Zhang; Wentao Dong; Xiaobin Tian; Chuan Ye; Yanlin Li; Yuekun Gong Oxidative stress damage is a common problem in bone marrow mesenchymal stem cell (BMSC) transplantation. Under stress conditions, the mitochondrial function of BMSCs is disrupted...
Includes: Supplementary data
Articles
Journal:
Bioscience Reports
Biosci Rep (2021) 41 (12): BSR20210977.
Published: 08 December 2021
... of high sugar and high-fat diet (HSFD) and streptozotocin (STZ). The T2DM rats were administrated with low (2 g.kg −1 ) and high (5 g.kg −1 ) doses of MFAE for 60 consecutive days. The biochemical indices of glucose metabolism disorders, insulin resistance and oxidative stress were observed. The results...
Articles
Xinhui Liu, Ruyu Deng, Xian Wei, Yuzhi Wang, Jiali Weng, Yunlan Lao, Jiandong Lu, Guoliang Xiong, Shunmin Li
Journal:
Bioscience Reports
Biosci Rep (2021) 41 (10): BSR20211598.
Published: 22 October 2021
... lesions and ameliorate renal fibrosis in CKD rats. Administration of PE and JPYSF enhanced sirtuin 3 (SIRT3) expression, inhibited mitochondrial fission, promoted mitochondrial fusion, and suppressed oxidative stress in the kidney of CKD rats. In conclusion, combined use of PE and JPYSF protected against...
Includes: Supplementary data
Articles
Journal:
Bioscience Reports
Biosci Rep (2021) 41 (9): BSR20210398.
Published: 22 September 2021
...% fluorescein isothiocyante (FITC) applied to the skin, followed by an ovalbumin (OVA) airway challenge. In addition, by examining serum immunoglobulin (Ig) concentrations, airway cytokines, the levels of oxidative stress markers, histopathological changes in lung tissue and airway hyperresponsiveness (AHR), we...
Includes: Supplementary data
Articles
Isabel Witvrouwen, Dominique Mannaerts, Jessica Ratajczak, Evi Boeren, Ellen Faes, Amaryllis H. Van Craenenbroeck, Yves Jacquemyn, Emeline M. Van Craenenbroeck
Journal:
Bioscience Reports
Biosci Rep (2021) 41 (8): BSR20210874.
Published: 12 August 2021
... pregnancies (HPs), and their relation with vascular function, oxidative stress (OS) and systemic inflammation. In this case–control study, 24 women with early PE (<34 weeks) were compared with 30 women with HP. Circulating microRNA levels (RT-qPCR), OS and systemic inflammation were assessed in plasma...
Articles
Journal:
Bioscience Reports
Biosci Rep (2021) 41 (7): BSR-2018-1414_COR.
Published: 01 July 2021
...). 2021 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . Antioxidant Fibroblasts Neferine Oxidative stress Ultraviolet A ...
Articles
Journal:
Bioscience Reports
Biosci Rep (2021) 41 (7): BSR20200787.
Published: 29 June 2021
... improved cardiac dysfunction and hemodynamics, and attenuated cardiac fibrosis and hypertrophy via inhibiting oxidative stress in MI-induced HF rats. In the present study, MI in rats was induced by coronary artery ligation with sterile techniques as previously reported [ 21 ] because it is a much more...
Articles
Journal:
Bioscience Reports
Biosci Rep (2021) 41 (4): BSR-20180861_COR.
Published: 27 April 2021
... of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . apoptosis brain cadmium Fragaria ananassa oxidative stress This Correction follows an Expression of Concern relating to this article previously published by Portland Press. ...
Articles
Wei Gao, Yongxun Jin, Jindong Hao, Siyi Huang, Dongxu Wang, Fushi Quan, Mingjun Zhang, Jiabao Zhang, Wenzhi Ren, Xianfeng Yu
Journal:
Bioscience Reports
Biosci Rep (2021) 41 (4): BSR20203091.
Published: 22 April 2021
... indicate that exposure to 20 µM HU caused significant oxidative stress and apoptosis of MII oocytes during maturation, which affected their developmental ability. These results provide valuable information for safety assessments of HU. Correspondence: Wenzhi Ren ( [email protected] ) or Xianfeng Yu...
Includes: Supplementary data
Articles
Journal:
Bioscience Reports
Biosci Rep (2021) 41 (3): BSR-20180861_EOC.
Published: 26 March 2021
... apoptosis brain cadmium Fragaria ananassa oxidative stress The Editorial Office has been made aware of potential issues surrounding the scientific validity of this paper, hence has issued an expression of concern to notify readers whilst the Editorial Office investigates. © 2021...
Articles
Journal:
Bioscience Reports
Biosci Rep (2021) 41 (2): BSR-20181414_EOC.
Published: 17 February 2021
... © 2021 The Author(s). 2021 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . Antioxidant Fibroblasts Neferine Oxidative stress Photoaging Ultraviolet...
Articles
Journal:
Bioscience Reports
Biosci Rep (2021) 41 (2): BSR20203955.
Published: 12 February 2021
... enrichment analysis were carried out by the Database for Annotation, Visualization and Integrated Discovery (DAVID) database. Furthermore, KGN cells were performed to validate the predicted results in oxidative stress (OS) model, and antioxidant effect was examined. Results: A total of 70 potential common...
Articles
Journal:
Bioscience Reports
Biosci Rep (2021) 41 (1): BSR20203219.
Published: 29 January 2021
...Zhenling Ma; Wenwen Zhang; Yaru Wu; Menghao Zhang; Lei Wang; Yihan Wang; Yi Wang; Wei Liu The excessive and inappropriate production of reactive oxygen species (ROS) can cause oxidative stress and is implicated in the pathogenesis of lung cancer. Cyclophilin A (CypA), a member of the immunophilin...
Articles
Journal:
Bioscience Reports
Biosci Rep (2020) 40 (10): BSR20201308.
Published: 30 October 2020
..., UCH-L1 inhibitor LDN-57444 suppressed mouse oocyte maturation by improving oxidative stress, attenuating mitochondrial function, curbing spindle body formation and down-regulating extracellular signal-related kinases (ERK1/2) expression, providing a deep insight into the cellular and molecular basis...
Articles
Christopher P. Hedges, Toan Pham, Bhoopika Shetty, Stewart W.C. Masson, Anthony J.R. Hickey, Peter R. Shepherd, Troy L. Merry
Journal:
Bioscience Reports
Biosci Rep (2020) 40 (10): BSR20201128.
Published: 16 October 2020
... T method, and reported as fold change (relative to VEH). BYL-719 free radicals mitochondrial respiration oxidative stress phosphoinositide 3-kinase Mitochondria play a central role in coordinating cellular homoeostasis [ 1 ], and are putative mediators of health and disease...
Includes: Supplementary data
Articles
Journal:
Bioscience Reports
Biosci Rep (2020) 40 (10): BSR20194347.
Published: 14 October 2020
...Jinzi Zhou; Fenghua Chen; Aimin Yan; Xiaobo Xia Age-related macular degeneration (AMD) is a progressive and degenerative ocular disease associated with oxidative stress. Madecassoside (MADE) is a major bioactive triterpenoid saponin that possesses antioxidative activity. However, the role of MADE...
Articles
Journal:
Bioscience Reports
Biosci Rep (2020) 40 (8): BSR-20180515_EOC.
Published: 04 August 2020
... © 2020 The Author(s). 2020 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . cadmium oxidative stress antioxidant grape seed proanthocyanidins Nrf2/HO...
Articles
Journal:
Bioscience Reports
Biosci Rep (2020) 40 (7): BSR20193566.
Published: 17 July 2020
...Meng Zhang; Tai Zhang; Yanan Tang; Guiyun Ren; Yanning Zhang; Xiangyu Ren Ultraviolet (UV) radiation-induced photoaging is one of the contributors to skin aging. UV light triggers oxidative stress, producing a large number of matrix metalloproteinases (MMPs) and degrading the extracellular matrix...
Articles
Journal:
Bioscience Reports
Biosci Rep (2020) 40 (7): BSR20201812.
Published: 30 June 2020
.... Hemodynamic parameters including blood pressure and heart rate were measured. The histopathologic evaluation of kidney tissues was performed. Lactate, creatine kinase, inflammatory cytokines and oxidative stress indicators were determined. Using Seahorse analysis, the metabolic analysis of mitochondrial...
Articles
Journal:
Bioscience Reports
Biosci Rep (2020) 40 (6): BSR20200471.
Published: 17 June 2020
...) and MAPK (JNK, ERK, and p38) signaling pathways. Similar alterations for oxidative stress and inflammation parameters were also detected in TNF-α-treated HaCaT cells. In addition, cimifugin-induced down-regulation of ICAM-1 were observed in TNF-α-treated cells. Altogether, our findings suggest...
Articles
Journal:
Bioscience Reports
Biosci Rep (2020) 40 (5): BSR20193917.
Published: 20 May 2020
... of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . Benign paroxysmal positional vertigo oxidative stress recurrence superoxide dismutases Peripheral serum samples were collected from the BPPV group at the admission (during vertigo attack...
Articles
Journal:
Bioscience Reports
Biosci Rep (2020) 40 (4): BSR20194032.
Published: 17 April 2020
...Jin Yan; Disi Deng; Yeke Wu; Keming Wu; Jie Qu; Fei Li Disrupted follicular development may result in increased follicular atresia, which is a crucial mechanism of various ovarian pathologies. It has been demonstrated that oxidative stress is associated with disrupted follicular development...
Articles
Qilong Liang, Jun Yang, Jiaji He, Xiaoling Chen, Hong Zhang, Maolin Jia, Kai Liu, Chuangchuang Jia, Yanhong Pan, Jinwang Wei
Journal:
Bioscience Reports
Biosci Rep (2020) 40 (4): BSR20192133.
Published: 15 April 2020
... and cleaved caspase-3 expression, and up-regulate Bcl-Xl expression. Conclusion: Stigmasterol protects the brain from brain I/R damage by reducing oxidative stress and inflammation. Correspondence: Jinwang Wei ( [email protected] ) 17 07 2019 27 02 2020 01 03 2020 09 03 2020...
Articles
Journal:
Bioscience Reports
Biosci Rep (2020) 40 (4): BSR20200040.
Published: 03 April 2020
... of MI rats and CFs with Ang II treatment. The results demonstrated that apelin-13 improved cardiac dysfunction, impaired cardiac hemodynamics, and attenuated fibrosis of CFs induced by Ang II via inhibiting the PI3K/Akt signaling pathway to inhibit oxidative stress. © 2020 The Author(s). 2020...
Articles
Journal:
Bioscience Reports
Biosci Rep (2020) 40 (4): BSR20193006.
Published: 31 March 2020
...Xiaomin Liu; Xiaowen Zhao; Rong Cheng; Yusen Huang Purpose: Autophagic dysfunction and abnormal oxidative stress are associated with cataract. The purpose of the present study was to investigate the changes of cellular autophagy and oxidative stress and their association in lens epithelial cells...
Includes: Supplementary data
Articles
Huanping Wang, Huizhen Chen, Yang Gao, Shengju Wang, Xian Wang, Xiaomei Tang, Wei Fang, Xiaoyan Shi, Jia Yao, Qiu Chen
Journal:
Bioscience Reports
Biosci Rep (2020) 40 (2): BSR20191260.
Published: 18 February 2020
... were not statistically significant. Conclusion: Our results suggested that Wuling capsule ameliorated the depression in patients with T2DM, and also improved the state of inflammation and oxidative stress state. These results also strongly indicated the ability of clinical transformation of Wuling...
Articles
Journal:
Bioscience Reports
Biosci Rep (2020) 40 (2): BSR20193524.
Published: 07 February 2020
... of oxycodone in cancer cells. Materials and Methods: Proliferation, survival and migration assays were performed on multiple types of cancer cells. Epithelial growth factor receptor (EGFR)/ERK/Akt pathway and oxidative stress were investigated after oxycodone treatment. Results: Oxycodone can either stimulate...
Articles
Journal:
Bioscience Reports
Biosci Rep (2020) 40 (1): BSR20193667.
Published: 29 January 2020
...Xiaoli Xu; Huimin Huang; Xiangyi Yin; Hongmei Fang; Xiaoyue Shen We aimed to investigate the regulatory mechanism of lentivirus-mediated overexpression of cystic fibrosis transmembrane conductance regulator (CFTR) in oxidative stress injury and inflammatory response in the lung tissue of mouse...
Articles
Weifeng Yao, Xiaoyu Lin, Xue Han, Lanfen Zeng, Anshun Guo, Yu Guan, Ziqing Hei, Jianpei Liu, Pinjie Huang
Journal:
Bioscience Reports
Biosci Rep (2020) 40 (1): BSR20191043.
Published: 24 January 2020
...). Inflammation Intestinal Ischemia/Reperfusion Injury Oxidative stress Ischemia/reperfusion (I/R) injury occurs in a tissue that undergoes a period of blood flow restriction followed by restoration [ 1 ]. The intestine is one of the organs that is most susceptible to I/R injury, which...
Includes: Supplementary data
Articles
Journal:
Bioscience Reports
Biosci Rep (2019) 39 (12): BSR20193190.
Published: 23 December 2019
... death and cardiac dysfunction. Studies have shown that oxidative stress is an important mechanism for this maladaptation. Cyclophilin A (CyPA) is a member of the cyclophilin (CyPs) family. Many cells secrete CyPA to the outside of the cells in response to oxidative stress. CyPA from blood vessels...
Articles
Journal:
Bioscience Reports
Biosci Rep (2019) 39 (11): BSR20192501.
Published: 13 November 2019
... independent experiments, n =5. * P <0.05. To examine the effect of scutellarin on H/R-induced oxidative stress in hepatocytes, the levels of ROS and MDA, as well the SOD activity were measured. As shown in Figure 2 A,C, the levels of ROS and MDA were significantly elevated in H/R-stimulated...
Includes: Supplementary data
Articles
Journal:
Bioscience Reports
Biosci Rep (2019) 39 (9): BSR20191711.
Published: 20 September 2019
... through inducing oxidative stress injury. The present study provides new knowledge on NP cell senescence and helps us to better understand the mechanism of disc degeneration. Correspondence: Haopeng Li ( [email protected] ) 27 05 2019 16 08 2019 23 08 2019 30 08 2019 ©...
Articles
Journal:
Bioscience Reports
Biosci Rep (2019) 39 (8): BSR20191601.
Published: 28 August 2019
... Cryopreservation oxidative stress reactive oxygen species The ability to keep an organism alive while frozen and allowing it to survive for a prolonged period of time may sound like a scene lifted directly from a science fiction movie. Although freezing complex multicellular organisms remains challenging...
Articles
Journal:
Bioscience Reports
Biosci Rep (2019) 39 (8): BSR20190109.
Published: 19 August 2019
... apoptosis by inhibiting oxidative stress and activate the PI3K/Akt/caspase-3 signaling pathway via GLP-1R. Correspondence: Li Zhi-hong ( [email protected] ) 12 01 2019 04 07 2019 01 08 2019 05 08 2019 © 2019 The Author(s). 2019 This is an open access article published...
Articles
Journal:
Bioscience Reports
Biosci Rep (2019) 39 (8): BSR20190689.
Published: 15 August 2019
...Timin Ni; Wanju Yang; Yiqiao Xing Age-related macular degeneration (AMD) is now one of the leading causes of blindness in the elderly population and oxidative stress-induced damage to retinal pigment epithelial (RPE) cells occurs as part of the pathogenesis of AMD. In the present study, we...
Articles
Xiaonan Zhang, Shaoyang Dong, Qiujin Jia, Ao Zhang, Yanyang Li, Yaping Zhu, Shichao Lv, Junping Zhang
Journal:
Bioscience Reports
Biosci Rep (2019) 39 (8): BSR20190788.
Published: 02 August 2019
..., oxidative stress, and inflammation. VR is commonly found in ischemic heart disease (IHD), hypertensive heart disease (HHD), diabetic cardiomyopathy (DCM), antineoplastic drug cardiotoxicity (CTX), and other CVDs. Therefore, we will review the relevant mechanisms of the miR-30 in VR induced by various...
Articles
Yifan Wang, Zhexing Shou, Heng Fan, Meng Xu, Qianyun Chen, Qing Tang, Xingxing Liu, Hui Wu, Man Zhang, Ting Yu, Shuangjiao Deng, Yujin Liu
Journal:
Bioscience Reports
Biosci Rep (2019) 39 (7): BSR20182297.
Published: 19 July 2019
... that OMT treatment could protect the integrity of the epithelial barrier, relieve oxidative stress, inhibit the expression of inflammatory mediators and pro-inflammatory cytokines, restrain the differentiation of Th17 cells and promote the differentiation of Treg cells via inhibition of the RhoA/ROCK...
Articles
Journal:
Bioscience Reports
Biosci Rep (2019) 39 (6): BSR20190166.
Published: 20 June 2019
... 1.4 ± 1.0 1.3 ± 0.9 0.51 Symbol digit test 31.5 ± 10.8 32.4 ± 9.7 0.50 * P <0.05. Postoperative cognitive dysfunction hip fracture malondialdehyde oxidative stress biomarker Postoperative cognitive dysfunction (POCD), a condition that has been poorly...
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