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Keywords: prognosis
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Articles
Biosci Rep (2021) BSR20212026.
Published: 18 November 2021
... in patients with OV. The low expression of ZNF76 was associated with worse survival in OV. Multivariable analysis showed that the low expression of ZNF76 was an independent factor predicting poor outcome in OV. The prognosis value of ZNF76 in pan-cancer was validated from multiple cohorts using the PrognoScan...
Articles
Biosci Rep (2021) BSR20212300.
Published: 11 November 2021
..., we analyzed the expression profiles and prognostic value of THUMPD1 in pan-cancer and gained insights into the correlation between THUMPD1 expression level and immunotherapy efficacy. Methods: Gene expression pattern and its correlation with prognosis, immune cell infiltration in pan-cancer were...
Articles
Biosci Rep (2021) 41 (8): BSR20211451.
Published: 27 August 2021
... the Creative Commons Attribution License 4.0 (CC BY) . clear cell renal cell carcinoma (ccRCC) glycolysis long noncoding RNAs (lncRNAs) prognosis risk model Renal cell carcinoma (RCC) is a common lethal urologic malignancy with over 430000 new cases and approximately 180000 deaths per year...
Includes: Supplementary data
Articles
Biosci Rep (2021) 41 (8): BSR20181627.
Published: 12 August 2021
...Wei Liu; Qin-Peng Wang; Jia Guo Several studies demonstrated that lncRNA differentiation antagonizing non-protein coding RNA (lncRNA DANCR) expression might have the potential capacity to predict the cancer prognosis; however, definite conclusion has not been obtained. The aim of this meta-analysis...
Includes: Supplementary data
Articles
Biosci Rep (2021) 41 (8): BSR20203531.
Published: 05 August 2021
...Anze Yu; Kai Guo; Qilin Qin; Changsheng Xing; Xiongbing Zu Background: Evaluation of the feasibility for osteopontin (OPN) to serve as a biomarker in the prognosis and clinical-pathological features of prostate cancer (PCA) patients. Methods: The original publications related to OPN and PCA were...
Includes: Supplementary data
Articles
Biosci Rep (2021) 41 (8): BSR20204401.
Published: 02 August 2021
...-analysis was used to explore the correlation between SII and prognosis in pancreatic carcinoma patients. Methods: PubMed, Embase and Cochrane Library databases were screened from inception to May 2020. Studies describing the prognostic role of SII in pancreatic carcinoma were then retrieved. The pooled...
Articles
Biosci Rep (2021) 41 (8): BSR20210866.
Published: 02 August 2021
.... Objective: We aimed to assess the level of serum NSE to predict prognosis and treatment response in patients with advanced or metastatic non-neuroendocrine NSCLC. Methods: We retrospectively analyzed 363 patients with advanced and metastatic NSCLC between January 2011 and October 2016. The serum NSE level...
Articles
Biosci Rep (2021) 41 (7): BSR20211175.
Published: 28 July 2021
...Yurong Zhu; Zhifa Zhang; Hui Peng; Weiping Li; Shaowei Hu; Min Zhao; Weifeng Lin Background: We conducted this research to investigate the relationship between long intergenic non-protein coding RNA 673 (linc00673) expression and prognosis and clinicopathological parameters in human malignancies...
Includes: Supplementary data
Articles
Biosci Rep (2021) 41 (7): BSR20210158.
Published: 28 July 2021
... 2021 15 07 2021 © 2021 The Author(s). 2021 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . bioinformatics Head and neck cancer Immune Prognosis...
Includes: Supplementary data
Articles
Biosci Rep (2021) 41 (7): BSR-2018-0617_COR.
Published: 01 July 2021
... © 2021 The Author(s). 2021 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . gastric cancer Inhibitory kappa B Kinases nuclear factor kappa B prognosis...
Articles
Biosci Rep (2021) 41 (7): BSR20210154.
Published: 29 June 2021
... of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . coronary artery disease monocyte-to-albumin ratio mortality percutaneous coronary intervention prognosis Despite advances in prevention, diagnosis, and treatment of cardiovascular disease over...
Includes: Supplementary data
Articles
Biosci Rep (2021) 41 (7): BSR20210055.
Published: 28 June 2021
... with the poor prognosis of GC patients, the prognostic model was established in TCGA-STAD cohort, and validated in Gene Expression Omnibus (GEO) cohorts, with effectiveness in both HER2 positive and negative patients. DNA methylation was involved in the impact on prognosis. Cell cycle, immune-associated...
Includes: Supplementary data
Articles
Biosci Rep (2021) 41 (7): BSR20201551.
Published: 28 June 2021
... rates of patients. Results: miR-208a-5p, miR-296-5p and miR-1304-5p were screened as potential biomarkers. miR-208a-5p and miR-296-5p were shown to be associated with better survival of patients after Kaplan–Meier analysis, whereas miR-1304-5p overexpression indicated a poor survival prognosis...
Includes: Supplementary data
Articles
Biosci Rep (2021) 41 (6): BSR20210012.
Published: 08 June 2021
...Yongfeng Li; Xinmiao Rui; Daobao Chen; Haojun Xuan; Hongjian Yang; Xuli Meng Background: Long non-coding RNA associated with poor prognosis of hepatocellular carcinoma (AWPPH) is dysregulated in a variety of human cancers. However, the prognostic value of AWPPH in various cancers remains unclear...
Articles
Biosci Rep (2021) 41 (5): BSR20204148.
Published: 27 May 2021
... identified, CDK1 and CDC45 were associated with unfavorable HNSCC prognosis, and three potential small molecule drugs for treating HNSCC were identified. Increased CDK1 expression was confirmed in HNSCC cells, and menadione, the top predicted potential drug, exerted significant inhibitory effects against...
Articles
Biosci Rep (2021) 41 (5): BSR20210583.
Published: 27 May 2021
...Jukun Wang; Ke Han; Chao Zhang; Xin Chen; Yu Li; Linzhong Zhu; Tao Luo Purpose : ADME genes are genes involved in drug absorption, distribution, metabolism, and excretion (ADME). Previous studies report that expression levels of ADME-related genes correlate with prognosis of hepatocellular...
Articles
Biosci Rep (2021) 41 (5): BSR20210527.
Published: 27 May 2021
... associated with the prognosis may be used as independent prognostic factors for the overall survival time of NSCLC patients. The pathways enriched with DEGs in low-risk and high-risk groups were analyzed, and the enriched pathways were correlated significantly with immunosuppressive status...
Includes: Supplementary data
Articles
Biosci Rep (2021) 41 (5): BSR20210231.
Published: 21 May 2021
...Ding Zhou; Mengmeng Wang; Yu Zhang; Kai Wang; Min Zhao; Yan Wang; Xu Wang; Rutong Yu; Xiuping Zhou Glioma is the most common primary cancer in the central nervous system. Despite advances in surgery, radiotherapy and chemotherapy over the past decades, the prognosis of glioblastoma patients remains...
Articles
Biosci Rep (2021) 41 (5): BSR20203431.
Published: 14 May 2021
...Ke Han; Kun Qian; Teng Zhao; Xing Sheng Liu; Yi Zhang Purpose: The host’s immune response to malignant tumor is fundamental to tumorigenesis and tumor development. The immune score is currently used to assess prognosis and to guide immunotherapy; however, its association with lung cancer prognosis...
Articles
Biosci Rep (2021) 41 (4): BSR20204008.
Published: 30 April 2021
... License 4.0 (CC BY) . enhancer FOXP4 FOXP4-AS1 OV prognosis Ovarian cancer (OV) is the fifth malignant reproductive tumor in women leading to mortality [ 1 ]. The Surveillance, Epidemiology and End Results (SEER) Program reported United States would have 21750 new diagnosed cases...
Includes: Supplementary data
Articles
Biosci Rep (2021) 41 (4): BSR20204359.
Published: 22 April 2021
... the relationship between the expression of these genes and GC patient prognosis. Results: The Log rank test with both Cox regression and Kaplan–Meier survival analyses showed that ADAMTS 6 expression profile correlated with the GC patients clinical outcome. Patients with a high expression of ADAMTS 6 were...
Articles
Biosci Rep (2021) 41 (4): BSR20210328.
Published: 16 April 2021
... complement and coagulation cascades, metabolic pathways, antibiotic biosynthesis pathways, peroxisome proliferator-activated receptor signaling pathways, and pyruvate metabolism pathways. These results suggest that RBP4 may be a novel biomarker for HCC prognosis, and an indicator of low immune response...
Articles
Biosci Rep (2021) 41 (4): BSR-20192298_EOC.
Published: 07 April 2021
... © 2021 The Author(s). 2021 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . Breast cancer FOXA2 MicroRNA-942 Prognosis Progression The Editorial...
Articles
Biosci Rep (2021) 41 (4): BSR-20193515_EOC.
Published: 06 April 2021
... © 2021 The Author(s). 2021 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . DOT1L EPZ5676 Gastric cancer Prognosis The Editorial Office has been...
Articles
Biosci Rep (2021) 41 (4): BSR-20180617_EOC.
Published: 06 April 2021
... factor κB prognosis The Editorial Office has been made aware of potential issues surrounding the scientific validity of this paper, hence has issued an expression of concern to notify readers whilst the Editorial Office investigates. ...
Articles
Biosci Rep (2021) 41 (3): BSR20203945.
Published: 10 March 2021
...-based prognosis predictive model is effective and reliable in predicting prognosis for patients with HCC. Correspondence: Xiang-Yong Hao ( haoxy2007@lzu.edu.cn , haoxy-2008@163.com ) or Tao Wang ( wtdoctor831030@sina.com ) or Hui Cai ( goodcaihui@163.com ) * These authors contributed equally...
Includes: Supplementary data
Articles
Biosci Rep (2021) 41 (2): BSR20203336.
Published: 26 February 2021
... than that in TMB-low group and high macrophage infiltration was correlated with inferior survival outcome of GC patients. Lastly, the TMBPRS was constructed and GC patients with high TMBPRS had poor prognosis. Correspondence: ChunHui Cui ( drcuich@126.com ) or JinLong Yu ( yujinlong640506@163.com...
Includes: Supplementary data
Articles
Biosci Rep (2021) 41 (2): BSR20204043.
Published: 26 February 2021
... between the miR-142 and prognosis in solid tumors. A comprehensive search for relevant studies was conducted until 10 November 2020. Studies that investigated the prognostic significance of the miR-142 in solid tumors were included. The hazard ratio and 95% confidence interval were calculated using...
Articles
Biosci Rep (2021) 41 (2): BSR20202063.
Published: 19 February 2021
... on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . hepatocellular carcinoma MTHFD1L tumor microenvironment immune cell prognosis Biomarkers are urgently needed for the diagnosis of cancers, such as gastric cancer [ 1...
Articles
Biosci Rep (2021) 41 (1): BSR20203481.
Published: 27 January 2021
.... The present study aimed to construct regulatory network and seek the potential biomarkers of BC diagnosis and prognosis as well as the molecular therapeutic targets from the perspective of mitochondrial dysfunction. Methods: The microarray data of mitochondria-related encoding genes in BC cell lines were...
Includes: Supplementary data
Articles
Biosci Rep (2021) 41 (1): BSR20202133.
Published: 27 January 2021
... Commons Attribution License 4.0 (CC BY) . CXCL5 CXCR2 penile cancer prognosis tumor progression Penile cancer (PC) is a rare cancer in developed countries; however, its incidence rate is much higher in some regions of South America, Asia, and Africa [ 1 ]. Despite recent progress...
Includes: Supplementary data
Articles
Biosci Rep (2021) 41 (1): BSR20203231.
Published: 15 January 2021
...Wenfang Xu; Wenke Guo; Ping Lu; Duan Ma; Lei Liu; Fudong Yu The poor prognosis of hepatocellular carcinoma (HCC) calls for the development of accurate prognostic models. The growing number of studies indicating a correlation between autophagy activity and HCC indicates there is a commitment...
Articles
Biosci Rep (2021) 41 (1): BSR20203995.
Published: 14 January 2021
.... This meta-analysis synthesized existing data to clarify the association between FTX with cancer prognosis. Methods: PubMed, Embase, Cochrane library, Web of Science, Chinese CNKI, and the Chinese WanFang databases were used to search for relevant studies. The role of FTX in cancers was evaluated by pooled...
Includes: Supplementary data
Articles
Biosci Rep (2021) 41 (1): BSR20203051.
Published: 07 January 2021
...Yuemei Feng; Guanzhang Li; Zhongfang Shi; Xu Yan; Renpeng Li; You Zhai; Yuanhao Chang; Di Wang; Ulf Dietrich Kahlert; Wei Zhang; Fang Yuan Glioma is the most common and malignant cancer of the central nervous system, and the prognosis is poor. Metabolic reprogramming is a common phenomenon...
Articles
Biosci Rep (2021) 41 (1): BSR20203944.
Published: 05 January 2021
...Hang Tong; Tinghao Li; Shun Gao; Hubin Yin; Honghao Cao; Weiyang He Bladder cancer is a common malignant tumour worldwide. Epithelial–mesenchymal transition (EMT)-related biomarkers can be used for early diagnosis and prognosis of cancer patients. To explore, accurate prediction models...
Articles
Biosci Rep (2020) 40 (12): BSR20201822.
Published: 21 December 2020
...Yingkun Ren; Zhiling Wang; Jianguo Xie; Peijun Wang Purposes : Several studies have reported that elevated red cell distribution width (RDW) is related to poor prognosis in several cancers; however, the prognostic significance of perioperative RDW in patients with rectal cancer that received...
Articles
Biosci Rep (2020) 40 (12): BSR20201529.
Published: 14 December 2020
...Bin Liu; Shuqiang Yao; Jiping Zhou Osteosarcoma (OS) is the most common bone malignancy in both children and adolescents. In the present study, we aimed to explore the association of miRNA-122 and miRNA-96 expression with the clinical characteristics and prognosis of patients with osteosarcoma...
Articles
Biosci Rep (2020) 40 (12): BSR20202463.
Published: 02 December 2020
..., and ADAMTS9-AS1) could serve as independent risk factors. We established a risk prediction model with these lncRNAs. Kaplan–Meier curve analysis showed that high-risk patients’ prognosis was lower than that of low-risk patients ( P =0.001). The present study provides novel insights into the lncRNA-mediated...
Includes: Supplementary data
Articles
Biosci Rep (2020) 40 (12): BSR20202938.
Published: 02 December 2020
... as a promising biomarker used to predict the worse prognosis of cancer patients. Correspondence: Weijie Zhang ( zhangweijie@suda.edu.cn ) or Jianquan Hou ( sdfyyhou123@163.com ) * These authors contributed equally to this work and shall share first authorship. 20 08 2020 17 11 2020 18...
Articles
Biosci Rep (2020) 40 (11): BSR20201704.
Published: 23 November 2020
...Wei Han; Biao Huang; Xiao-Yu Zhao; Guo-Liang Shen Skin cutaneous melanoma (SKCM) is one of the most deadly malignancies. Although immunotherapies showed the potential to improve the prognosis for metastatic melanoma patients, only a small group of patients can benefit from it. Therefore...
Includes: Supplementary data
Articles
Biosci Rep (2020) 40 (11): BSR20190372.
Published: 13 November 2020
... Neoplasm prognosis Malignant tumors pose a great threat to human health [ 1 ]. Each year, there are approximately 14 million new cases of malignant tumors worldwide and more than 8.2 million deaths [ 2 , 3 ]. The prognosis for cancers is still poor, the difficulties of early cancer diagnosis...
Articles
Biosci Rep (2020) 40 (10): BSR20202649.
Published: 30 October 2020
...Muhu Chen; Xue Chen; Yingchun Hu; Xianfu Cai Sepsis is a common clinical disease with high mortality, and patients with sepsis have varied prognoses. Researchers need to explore the underlying mechanisms that determine the prognosis of sepsis. Hence, a mouse model was used to evaluate new potential...
Articles
Biosci Rep (2020) 40 (10): BSR20202812.
Published: 28 October 2020
... with a poor prognosis of grade II–III gliomas. By combing the data from Hou et al. study [ 3 ] and the data from The Cancer Genome Atlas (TCGA) and CGGA databases, we performed a meta-analysis. The result (HR = 1.71, 95% confidence interval = 1.33–2.21) suggested that high expression of CD44 is associated...
Articles
Biosci Rep (2020) 40 (10): BSR20201012.
Published: 28 October 2020
...Ming Wu; Yu Xia; Yadong Wang; Fei Fan; Xian Li; Jukun Song; Jie Ding Purpose : Stomach adenocarcinoma (STAD) is one of the most common malignant tumors, and its occurrence and prognosis are closely related to inflammation. The aim of the present study was to identify gene signatures and construct...
Includes: Supplementary data
Articles
Biosci Rep (2020) 40 (10): BSR20202544.
Published: 21 October 2020
...Xiangxiang Liu; Zhongke Huang; Xianghui He; Xiangqian Zheng; Qiang Jia; Jian Tan; Yaguang Fan; Cen Lou; Zhaowei Meng Background: Papillary thyroid cancer (PTC) is a very common malignant disease with high morbidity. We needed some pretreatment indicators to help us predict prognosis and guide...
Articles
Biosci Rep (2020) 40 (10): BSR20202603.
Published: 16 October 2020
... prognosis tumor-infiltrating Hepatocellular carcinoma (HCC) is the third leading cause of cancer-related mortality worldwide [ 1 ]. The 5-year survival rate of patients with advanced liver cancer is poor due to high tumor recurrence, metastasis, and the lack of early diagnostic biomarkers with high...
Includes: Supplementary data
Articles
Biosci Rep (2020) 40 (10): BSR20192593.
Published: 05 October 2020
... they were independent prognostic factors for OS of HCC patients. Conclusions: In summary, different expression of methylated genes above mentioned were associated with better prognosis in HCC patients. Altering the methylation status of these genes may be a therapeutic target for HCC, but it should...
Articles
Biosci Rep (2020) 40 (9): BSR20200492.
Published: 16 September 2020
... that DEGs participated mainly in pathways such as ‘valine, leucine and isoleucine degradation’, ‘fatty acid metabolism’, ‘PPAR signaling pathway’, ‘glycolysis/gluconeogenesis’, and ‘tryptophan metabolism’. bioinformatic analysis clear cell renal carcinoma prognosis As one of the most common...
Includes: Supplementary data
Articles
Biosci Rep (2020) 40 (9): BSR20202537.
Published: 10 September 2020
... gene in the treatment of breast cancer. bioinformation breast cancer PITX1 prognosis Oncomine ( http://www.oncomine.org ), a cancer microarray database and web-based data mining platform, aims to compare the transcriptome data with normal tissues in most major types of cancer...
Articles
Biosci Rep (2020) 40 (9): BSR20192436.
Published: 04 September 2020
... targets for prognosis and early intervention in ARDS. Methods: The mRNA expression profile of GSE89953 was obtained from the Gene Expression Omnibus database. The LIMMA package in R software was used to identify differentially expressed genes (DEGs), and the clusterProfiler package was used for functional...