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Keywords: prostate cancer
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Biosci Rep (2022) 42 (1): BSR20211972.
Published: 11 January 2022
...M.Y. Cynthia Stafford; Colin E. Willoughby; Colum P. Walsh; Declan J. McKenna Elevated levels of miR-21 expression are associated with many cancers, suggesting it may be a promising clinical biomarker. In prostate cancer (PCa), however, there is still no consensus about the usefulness of miR-21...
Includes: Supplementary data
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Biosci Rep (2021) 41 (5): BSR20204203.
Published: 27 May 2021
...Yeu-Sheng Tyan; Yen-Po Lee; Hui-Yen Chuang; Wei-Hsun Wang; Jeng-Jong Hwang Androgen deprivation therapy (ADT) is one of the typical treatments used for patients with prostate cancer (PCa). ADT, however, may fail when PCa develops castration-resistance. Fatty acid synthase (FASN), a critical enzyme...
Includes: Supplementary data
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Biosci Rep (2021) 41 (1): BSR20201533.
Published: 04 January 2021
...Jukun Song; Wei Wang; Yiwen Yuan; Yong Ban; Jiaming Su; Dongbo Yuan; Weihong Chen; Jianguo Zhu Immune infiltration in Prostate Cancer (PCa) was reported to be strongly associated with clinical outcomes. However, previous research could not elucidate the diversity of different immune cell types...
Includes: Supplementary data
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Biosci Rep (2020) 40 (8): BSR20193287.
Published: 13 August 2020
...Shangwen Xiao; Bin Song Long non-coding RNAs (lncRNAs) act as crucial modulators during the development of diverse cancers. Although various types of lncRNAs in prostate cancer (PCa) have been explored, quantities of lncRNAs still wait to be exploited. The present study is to probe the functions...
Includes: Supplementary data
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Biosci Rep (2020) 40 (5): BSR20191028.
Published: 07 May 2020
..., including cancer. METHODS: We utilized The Cancer Genome Atlas (TCGA) and other publicly available databases for miRs and mRNA expression in prostate cancer, selected miR-484 and investigated its role in prostate cancer biology and disease progression using in vitro studies. RESULTS: Our data mining efforts...
Includes: Supplementary data
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Biosci Rep (2019) 39 (8): BSR20170770.
Published: 23 August 2019
...Jie Liu; Zhiyuan Chen; Jia Guo; Lei Wang; Xiuheng Liu Prostate cancer (PCa), the second most mortal cancer from developed countries, presents a high level of chemoresistance. There is emerging evidence underscores the critical role of autophagy in the onset, progression, and chemoresistance of PCa...
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Biosci Rep (2019) 39 (6): BSR20181826.
Published: 25 June 2019
... metabolism, has been reported to play crucial roles in cancer development. However, the precise function of GLS in prostate cancer (PCa) remains unclear. The purpose of the present study was to assess the GLS expression and its clinical significance in PCa. We found that GLS was significantly up-regulated...
Includes: Supplementary data
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Biosci Rep (2019) 39 (5): BSR20182171.
Published: 10 May 2019
... of CAFs. In conclusion, these results demonstrate that MPSSS can not only effectively inhibit the growth of prostate cancer as we previously reported but also alter the function of prostate CAFs by activating the TLR4-NF-κB pathway, providing a new strategy for the comprehensive treatment of tumors...
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Biosci Rep (2019) 39 (4): BSR20181854.
Published: 05 April 2019
...Zhaoli Zhang; Ran Cui; Hui Li; Jinlong Li Accumulating evidence suggests that miRNAs play a crucial role in the development of prostate cancer (PC); however, the role of miR-500 in PC remains poorly understood. The data presented here reveal abnormal increases in miR-500 expression in PC tissues...
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Biosci Rep (2018) 38 (5): BSR20171571.
Published: 31 October 2018
...Xiaochen Zhou; Qiong Chen; Haolin Wang; Cheng Zhang; Bin Fu; Gongxian Wang The aim of the present study was to explore the expression profile and the potential regulatory mechanism of two long non-coding RNAs (lncRNAs) (RP13-650J16.1 and TCONS_00023979) in prostate cancer (PCa). Expression profile...
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Biosci Rep (2016) 36 (6): e00423.
Published: 09 December 2016
.... Both Geltrex® coating and tissue-specific primary cell medium were permanently required to successfully maintain primary epithelial prostate cancer cells (PEPCs) in culture. In case of primary epithelial breast cancer cells (PEBCs), collagen I coating enabled to obtain comparable number of passages...
Includes: Supplementary data
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