... protein-protein interactions Emerging evidence implicates repressive H3K9 methylation as an important transcriptional regulatory and epigenetic pathway in tumorigenesis [ 1 ]. H3K9 methylation is driven by at least 6 distinct SET domain-containing enzymes; namely SUV39H1 and SUV39H2, which...

... proteins protein-protein interactions YY1 HDXMS was employed to assess YY1 backbone dynamics when in the apo form or when bound to ∼3× molar excess DNA. This was done to better understand the mechanisms behind the interplay between DNA binding and oligomerisation of YY1. Briefly, the peptides...

...Rodolfo Gamaliel Avila-Bonilla; Jorge Antonio Velazquez-Guzman; Eimy Itzel Reyes-Zepeda; Jorge Luis Gutierrez-Avila; César A Reyes-López; Alondra Cisneros-Sarabia; Emma Saavedra; Angel Lopéz-Sandoval; Esther Ramírez-Moreno; César López-Camarillo; Laurence A. Marchat Protein–protein interactions...

... reabsorption protein-protein interactions More than 1.1 billion people worldwide have hypertension [ 1 , 2 ], which is the main risk factor for stroke, coronary heart disease, kidney disease and other diseases, and responsible for estimated 7.8 million deaths worldwide in 2015 alone [ 3...

...-ribosyltransferase toxins enzyme mechanisms honey bee diseases macrophage cell entry protein-protein interactions ...

... cell entry protein-protein interactions Mono-ADP-ribosyltransferase (mART) toxins are an exoenzyme class used by pathogenic bacteria to confer damage to host cells [ 1–9 ]. These virulence factors function by binding an NAD + molecule and catalyzing the transfer of the ADP-ribose moiety...

... for the identification of direct protein–protein interactions (PPIs), with a lower rate of false-positive findings. A total of 27 baits for HAX1 were screened and gave rise to specific interactions. HAX1 also came out as a prey from 21 different baits (41 baits, including repeats). Nine different libraries were searched...

... access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . DLK1 NCOR1 non-small-cell lung cancer notch signalling pathway nuclear localization protein-protein interactions Lung...

... 2019 21 08 2019 20 09 2019 © 2019 The Author(s). 2019 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . protein-protein interactions ribosomal...

... microscopy influenza lipid membranes membranes protein-protein interactions viral matrix proteins The Influenza A virus (IAV) buds from the plasma membrane (PM) of infected cells and, while doing so, acquires a lipid envelope from its host [ 1–4 ]. During this step, the PM lipid bilayer...

... the Creative Commons Attribution License 4.0 (CC BY) . cellular localization exocytosis myosins protein-protein interactions trafficking transcription Class V myosins are processive motors that transport or tether vesicles, organelles, and macromolecules to actin filaments, and play key...

... that nuclear actin could operate as an interaction platform for nuclear AKT, connecting AKT to transcriptional activators/co-activators via protein–protein interaction to the transcriptional machinery. In a similar fashion, it has been described that the tyrosine kinase receptor ErbB2 translocates...

...Yu Zhao; Patrick R. Cushing; David C. Smithson; Maria Pellegrini; Alexandre A. Pletnev; Sahar Al-Ayyoubi; Andrew V. Grassetti; Scott A. Gerber; R. Kiplin Guy; Dean R. Madden Protein–protein interactions have become attractive targets for both experimental and therapeutic interventions. The PSD-95...

... Springer 2005 Functional proteomics mass spectrometry protein–protein interactions affinity-based strategies Abbreviations 1D-gel, monodimensional gel electrophoresis; 2D-gel, two-dimensional gel electrophoresis; AldA-NRE, Aldolase A negative regulatory element; ES-LC-MS/MS...