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Keywords: reactive oxygen species
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Articles
Qi Wang, Hui Zhang, Qian-qian Ren, Tian-he Ye, Yi-ming Liu, Chuan-sheng Zheng, Guo-feng Zhou, Xiang-wen Xia
Journal:
Bioscience Reports
Biosci Rep (2021) 41 (6): BSR20210442.
Published: 11 June 2021
... intracellular uptake of doxorubicin, cell viability, apoptosis, cell cycle, mitochondrial membrane potential (MMP), reactive oxygen species (ROS), and total antioxidant capacity. The results confirmed that sublethal hyperthermia enhanced the intracellular uptake of doxorubicin into hypoxic HepG2 cells...
Includes: Supplementary data
Articles
Journal:
Bioscience Reports
Biosci Rep (2021) 41 (1): BSR20203219.
Published: 29 January 2021
...Zhenling Ma; Wenwen Zhang; Yaru Wu; Menghao Zhang; Lei Wang; Yihan Wang; Yi Wang; Wei Liu The excessive and inappropriate production of reactive oxygen species (ROS) can cause oxidative stress and is implicated in the pathogenesis of lung cancer. Cyclophilin A (CypA), a member of the immunophilin...
Articles
Journal:
Bioscience Reports
Biosci Rep (2020) 40 (5): BSR20191994.
Published: 05 May 2020
... that dexmedetomidine inhibited H 2 O 2 -induced apoptosis and reactive oxygen species (ROS) in rat DRG neurons and in addition, dexmedetomidine down-regulated the expression levels of anaerobic glycolysis-related proteins, significantly reduced glucose, pyruvic acid and lactic acid levels. It also increased the ATP...
Articles
Milad Ashrafizadeh, Sara Javanmardi, Masoumeh Moradi-Ozarlou, Reza Mohammadinejad, Tahereh Farkhondeh, Saeed Samarghandian, Manoj Garg
Journal:
Bioscience Reports
Biosci Rep (2020) 40 (4): BSR20200257.
Published: 03 April 2020
... been demonstrated that resveratrol is able to significantly enhance the concentration of reactive oxygen species, leading to the mitochondrial dysfunction and consequently, apoptosis induction. A number of signaling pathways such as sirtuin and NF-κB may contribute to the mitochondrial-mediated...
Articles
Hypoxia induces rapid, STAT3 and ROS dependent, mitochondrial translocation of RelA(p65) and IκBα
Open Access
Journal:
Bioscience Reports
Biosci Rep (2019) 39 (9): BSR20192101.
Published: 16 September 2019
... of mitochondria revealed that only RelA was found in the mitoplast, the location of the mtDNA. We demonstrate that hypoxia leads to a very rapid but transient accumulation of RelA and IκBα in mitochondria. This effect required reactive oxygen species (ROS) but was not dependent on the hypoxia sensing...
Articles
Journal:
Bioscience Reports
Biosci Rep (2019) 39 (8): BSR20191601.
Published: 28 August 2019
... during the freezing and thawing process. Among such insults, the generation of supra-physiological levels of reactive oxygen species (ROS) could impair cellular functions and survival. Antioxidants are potential additives that were reported to partially or completely reverse freeze-thaw stress-associated...
Articles
Feilong Qi, Chen Zhang, Shanshan Jiang, Qian Wang, Kudelaidi Kuerban, Man Luo, Mengxue Dong, Xinguang Zhou, Laiming Wu, Biao Jiang, Li Ye
Journal:
Bioscience Reports
Biosci Rep (2019) 39 (6): BSR20190167.
Published: 14 June 2019
... and distributed under the Creative Commons Attribution License 4.0 (CC BY) . antifungal apoptosis metacaspase reactive oxygen species S-ethyl ethanethiosulfinate Natural products have increasingly popular applications in medicine and green agriculture due to their mild and largely harmless...
Includes: Supplementary data
Articles
Journal:
Bioscience Reports
Biosci Rep (2018) 38 (5): BSR20171492.
Published: 02 October 2018
...Véronique Larosa; Claire Remacle Reactive oxygen species (ROS) are highly reactive reduced oxygen molecules that result from aerobic metabolism. The common forms are the superoxide anion (O 2 ∙− ) and hydrogen peroxide (H 2 O 2 ) and their derived forms, hydroxyl radical (HO∙) and hydroperoxyl...
Articles
Lingdan Chen, Chunli Liu, Dejun Sun, Tao Wang, Li Zhao, Wenli Chen, Mingjie Yuan, Jian Wang, Wenju Lu
Journal:
Bioscience Reports
Biosci Rep (2018) 38 (4): BSR20180346.
Published: 03 July 2018
... resulted in reduced reactive oxygen species level, and it increased tube formation, nitric oxide (NO), and cGMP level. Moreover, miR-133a antagonism-induced angiogenesis was abolished by GCH1 inhibitor. In contrary, miR-133a overexpression impairs angiogenesis and it reduces GCH1, NO, and cGMP levels...
Articles
Activation of M1 macrophages plays a critical role in the initiation of acute lung injury
Open Access
Journal:
Bioscience Reports
Biosci Rep (2018) 38 (2): BSR20171555.
Published: 27 April 2018
...), and reactive oxygen species (ROS) significantly increased. Furthermore, the increase in cytokines was accompanied with the initiation of lung injury indicated by the decreased levels of SP-A and SP-B. In macrophage-depleted CD11b-DTR mice, ALI was attenuated, serum levels of IL-1β, TNF-α and ROS were reduced...
Articles
Oxidative stress regulates cellular bioenergetics in esophageal squamous cell carcinoma cell
Open AccessXiaolong Zhang, Linhua Lan, Lili Niu, Juping Lu, Changxi Li, Miaomiao Guo, Shouyong Mo, Jing Lu, Yongzhang Liu, Bin Lu
Journal:
Bioscience Reports
Biosci Rep (2017) 37 (6): BSR20171006.
Published: 12 December 2017
... (ESCC) cell line TE-1 and analyze its underlying mechanism. Western blot results showed that CoCl 2 and H 2 O 2 treatment of TE-1 cells led to significant reduction in mitochondrial respiratory chain complex subunits expression and increasing intracellular reactive oxygen species (ROS) production. We...
Includes: Supplementary data
Articles
Journal:
Bioscience Reports
Biosci Rep (2017) 37 (5): BSR20170685.
Published: 28 September 2017
... of propidium iodide (PI) staining solution (50 μg/ml PI in PBS containing 0.2 mg/ml of DNase free RNase A) for 1 h in darkness at 37°C. Finally, the cells were analyzed by a flow cytometer (Becton Dickinson, U.S.A.). Intracellular ROS level was determined by using the Reactive Oxygen Species Assay Kit...
Articles
Susceptibility of brown adipocytes to pro-inflammatory cytokine toxicity and reactive oxygen species
Open Access
Journal:
Bioscience Reports
Biosci Rep (2016) 36 (2): e00306.
Published: 03 March 2016
... metabolism and thereby exacerbate cellular dysfunction and promote diabetes progression. Therefore, the antioxidative enzyme status of a brown adipocyte cell line and its susceptibility towards pro-inflammatory cytokines, which participate in the pathogenesis of diabetes, and reactive oxygen species (ROS...
Includes: Supplementary data
Articles
Sublethal vancomycin-induced ROS mediating antibiotic resistance in Staphylococcus aureus
Open Access
Journal:
Bioscience Reports
Biosci Rep (2015) 35 (6): e00279.
Published: 24 December 2015
... resistance [ 15 ]. Nevertheless, although much progress has been made, how vancomycin resistance in S. aureus is precisely regulated needs further elucidation. In recent years, reactive oxygen species (ROS) have been proposed to be highly correlated with the antibiotics and bacterial killing [ 16...
Articles
Journal:
Bioscience Reports
Biosci Rep (2015) 35 (5): e00252.
Published: 29 September 2015
...Qingbin Zhao; Junfang Zhang; Huifang Wang AngII (angiotensin II)-induced excessive ROS (reactive oxygen species) generation and proliferation of VSMCs (vascular smooth muscle cells) is a critical contributor to the pathogenesis of atherosclerosis. PGC-1α [PPARγ (peroxisome-proliferator-activated...
Includes: Supplementary data
Articles
Journal:
Bioscience Reports
Biosci Rep (2014) 34 (6): e00164.
Published: 23 December 2014
... 12901, U.S.A. 5 To whom correspondence should be addressed (email [email protected] ). 1 9 2014 4 9 2014 23 10 2014 alternate RNA splicing Drosophila extracellular superoxide dismutase hydrogen peroxide oxygen free radical reactive oxygen species SOD...
Articles
Neuronal and astrocyte dysfunction diverges from embryonic fibroblasts in the Ndufs4 fky/fky mouse
Open AccessMatthew J. Bird, Xiaonan W. Wijeyeratne, Jasper C. Komen, Adrienne Laskowski, Michael T. Ryan, David R. Thorburn, Ann E. Frazier
Journal:
Bioscience Reports
Biosci Rep (2014) 34 (6): e00151.
Published: 21 November 2014
... ATP synthesis. In addition, increased ROS (reactive oxygen species) generation and altered sensitivity to cell death were only observed in Ndufs4 fky/fky primary MEFs. In contrast, Ndufs4 fky/fky primary isocortical neurons and primary isocortical astrocytes displayed only impaired ATP generation...
Includes: Supplementary data
Articles
Fibroblast-to-myofibroblast switch is mediated by NAD(P)H oxidase generated reactive oxygen species
Open Access
Journal:
Bioscience Reports
Biosci Rep (2014) 34 (1): e00089.
Published: 14 January 2014
... for MFs, is mediated by a TGFβ1-dependent increase in the intracellular level of ROS (reactive oxygen species). This report demonstrates two novel aspects of the TGFβ1 signalling cascade, namely the generation of ROS due to a biphasic NAD(P)H oxidase activity and a ROS-dependent downstream activation...
Articles
Journal:
Bioscience Reports
Biosci Rep (2013) 33 (3): e00041.
Published: 05 June 2013
...Tianhui Liu; Ping Wang; Min Cong; Youqing Xu; Jidong Jia; Hong You DDC (diethyldithiocarbamate) could block collagen synthesis in HSC (hepatic stellate cells) through the inhibition of ROS (reactive oxygen species) derived from hepatocyte CYP2E1 (cytochrome P450 2E1). However, the effect of DDC...
Articles
Angiopoietin-like 4: a decade of research
Available to Purchase
Journal:
Bioscience Reports
Biosci Rep (2012) 32 (3): 211–219.
Published: 22 December 2011
... wound healing, modulates vascular permeability, and regulates ROS (reactive oxygen species) level to promote tumorigenesis. The present review summarizes these landmark findings about ANGPTL4 and highlights several important implications for future clinical practice. Importantly, these implications have...
Articles
Participation of Chloroplasts in Plant Apoptosis
Available to PurchaseVitaly D. Samuilov, Elena M. Lagunova, Dmitry B. Kiselevsky, Elena V. Dzyubinskaya, Yana V. Makarova, Mikhail V. Gusev
Journal:
Bioscience Reports
Biosci Rep (2003) 23 (2-3): 103–117.
Published: 01 April 2003
... Photosynthesis respiration apoptosis chloroplasts mitochondria reactive oxygen species plastoquinone cytochrome b 6 f complex Pisum Bioscience Reports, Vol. 23, Nos. 2 and 3, April and June 2003 ( 2003) Participation of Chloroplasts in Plant Apoptosis Vitaly D. Samuilov,1,2 Elena M. Lagunova,1...
Articles
Real-Time Measurement of Intracellular Reactive Oxygen Species Using Mito Tracker Orange (CMH2TMRos)
Available to Purchase
Journal:
Bioscience Reports
Biosci Rep (2001) 21 (3): 341–352.
Published: 01 June 2001
... that CMH 2 TMRos detects primarily superoxide in cells even though the fluorophore can be oxidized by both superoxide and H 2 O 2 . © 2001 Plenum Publishing Corporation 2001 Reactive oxygen species arachidonic acid lysophosphatidic acid MitoTracker orange real-time measurement Bioscience...
Articles
Inhibition of Mitochondrial Permeability Transition by Low pH is Associated with Less Extensive Membrane Protein Thiol Oxidation
Available to Purchase
Journal:
Bioscience Reports
Biosci Rep (1999) 19 (6): 525–533.
Published: 01 December 1999
... transition acid pH protein sulfhydryl oxidation calcium reactive oxygen species Bioscience Reports, Vol. 19, No. 6, 1999 Inhibition of Mitochondrial Permeability Transition by Low pH is Associated with Less Extensive Membrane Protein Thiol Oxidation Bruna M. A. R. Teixeira,1 Alicia J. Kowaltowski,1,3...
Articles
How Do Bacteria Avoid High Oxygen Concentrations?
Available to Purchase
Journal:
Bioscience Reports
Biosci Rep (1997) 17 (3): 335–342.
Published: 01 June 1997
.... A novel protein, Aer, and the chemotaxis serine receptor, Tsr, have recently been identified as transducers for aerotaxis which monitor internal energy levels in the bacteria. © 1997 Plenum Publishing Corporation 1997 oxygen receptors bacterial chemotaxis reactive oxygen species signal...
Articles
Membrane-Linked Systems Preventing Superoxide Formation
Available to Purchase
Journal:
Bioscience Reports
Biosci Rep (1997) 17 (3): 347–366.
Published: 01 June 1997
.... © 1997 Plenum Publishing Corporation 1997 Reactive oxygen species mitochondria pore apoptosis uncoupling non-coupled respiration aconitase Bioscience Reports, Vol. 17, No. 3, 1997 REVIEW Membrane-Linked Systems Preventing Superoxide Formation Vladimir P. Skulachev Received January 17...
Articles
The Physiological Significance of Mitochondrial Proton Leak in Animal Cells and Tissues
Available to Purchase
Journal:
Bioscience Reports
Biosci Rep (1997) 17 (1): 9–16.
Published: 01 February 1997
... species and in different thyroid states. Such differences imply some function for proton leak and candidates for this function include thermogenesis, protection against reactive oxygen species, endowment of metabolic sensitivity and maintenance of carbon fluxes. Mitochondria proton leak Standard...
Articles
Mechanisms of Oxygen Taxis in Bacteria
Available to Purchase
Journal:
Bioscience Reports
Biosci Rep (1997) 17 (1): 77–83.
Published: 01 February 1997
... the discovery of the flavoprotein receptor which drives Escherichia coli towards oxygen. Possible mechanisms of oxygen sensing in various bacterial species are considered in connection with the existing, often fragmental, data on phototaxis, redox taxis and taxis repellent effect of the reactive oxygen species...
Articles
The Role of Reactive Oxygen Species in Mitochondrial Permeability Transition
Available to PurchaseAnibal E. Vercesi, Alicia J. Kowaltowski, Mercedes T. Grijalba, André R. Meinicke, Roger F. Castilho
Journal:
Bioscience Reports
Biosci Rep (1997) 17 (1): 43–52.
Published: 01 February 1997
...+ -stimulated production of reactive oxygen species (ROS) by the respiratory chain, at the level of the coenzyme Q. The ROS attack to membrane protein thiols produces cross-linkage reactions, that may open membrane pores upon Ca 2+ binding. Studies with submitochondrial particles have demonstrated...
Articles
Superoxide Production by the Mitochondrial Respiratory Chain
Available to Purchase
Journal:
Bioscience Reports
Biosci Rep (1997) 17 (1): 3–8.
Published: 01 February 1997
...Julio F. Turrens This mini-review describes the role of different mitochondrial components in the formation of reactive oxygen species under normal and pathological conditions and the effect of inhibitors and uncouplers on superoxide formation. © 1997 Plenum Publishing Corporation 1997...
Articles
A Possible Role of Slips in Cytochrome C Oxidase in the Antioxygen Defense System of the Cell
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Journal:
Bioscience Reports
Biosci Rep (1997) 17 (1): 23–31.
Published: 01 February 1997
... of cytochrome c oxidase represent an intrinsic switch mechanism which regulates the relative contribution of energy transfer and respiratory protection against oxygen toxicity by the oxidase. © 1997 Plenum Publishing Corporation 1997 Cytochrome c oxidase proton pumps reactive oxygen species...
Articles
UVB radiation affects the mobility of epidermal growth factor receptors in human keratinocytes and fibroblasts
Available to Purchase
Journal:
Bioscience Reports
Biosci Rep (1996) 16 (3): 227–238.
Published: 01 June 1996
...; KRG, Krebs-Ringer phosphate buffer; PBS, Phosphate-buffered saline; R, Mobile fraction; ROS, Reactive oxygen species; SEM, Standard error of the mean; SOD, Superoxide dismutase; UVA, Ultraviolet light-A (315–400 nm); UVB, Ultraviolet light-B (280–315 nm) Bioscience Reports, Vol. 16, No. 3, 1996 UVB...
Articles
Effect of reactive oxygen species on the erythrocyte calcium-pump function in protein-energy malnutrition
Available to Purchase
Journal:
Bioscience Reports
Biosci Rep (1992) 12 (6): 433–443.
Published: 01 December 1992
... and endogenous products of lipid peroxidation in erythrocyte membranes of normal and kwashiorkor (KWA) subjects and assessed the susceptibility of the membranes to exogenously generated reactive oxygen species. The modulation of the basal and calmodulin-stimulated calcium-pumping activity of these membranes...
