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Keywords: risk
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Articles
Biosci Rep (2021) 41 (1): BSR20191729.
Published: 04 January 2021
...Jiakai Jiang; Sheng Zhang; Weifeng Tang; Zhiyuan Qiu Previous studies suggested that miR-146a rs2910164 (C/G) locus was predicted to influence the risk of cancer. However, the relationship of miR-146a rs2910164 locus with colorectal cancer (CRC) susceptibility was controversial. We recruited 1003...
Includes: Supplementary data
Articles
Biosci Rep (2020) 40 (8): BSR20193895.
Published: 11 August 2020
... of single nucleotide polymorphisms (SNPs) in the interleukin-4 ( IL-4 ), IL-10 , and herpesvirus entry mediator ( HVEM ) genes in contributing to ESCC risk. IL-4, IL-10 , and HVEM SNPs were analyzed by employing an SNPscan method. After adjustment for body mass index (BMI), smoking, drinking, age and gender...
Articles
Biosci Rep (2020) 40 (7): BSR20193542.
Published: 24 July 2020
...Bo Zhou; Shufang Liu; Danni He; Kundi Wang; Yunfeng Wang; Ting Yang; Qi Zhang; Zhixin Zhang; Wenquan Niu Backgrounds: Some studies have reported association of circulating fibrinogen with the risk of chronic obstructive pulmonary disease (COPD), and the results are conflicting. To yield more...
Includes: Supplementary data
Articles
Biosci Rep (2020) 40 (7): BSR20201200.
Published: 15 July 2020
...Bin Chen; Wang-fa Zhu; Yi-yang Mu; Biao Liu; Hong-zhuo Li; Xiao-feng He Background: Many studies have reported the association between vitamin D receptor ( VDR ) polymorphism and osteoporosis risk. However, their results were conflicting. Six previous meta-analyses have been published to analyze...
Includes: Supplementary data
Articles
Biosci Rep (2020) 40 (7): BSR20191825.
Published: 09 July 2020
... risk of urinary system tumors and specific prostate cancers [TG vs. TT, TG+GG vs. TT and G vs. T; P <0.05, OR (odds ratio) <1]. FPRP and TSA data further confirmed these results. There was an increased risk of leukemia [G vs. T, GG vs. TT, and GG vs. TT+TG genotypes; P <0.05, OR>1...
Includes: Supplementary data
Articles
Biosci Rep (2020) 40 (5): BSR20190209.
Published: 20 May 2020
...) and PE risk. However, these associations were inconsistent in several studies. Therefore, we conducted this meta-analysis to assess the role of VEGF gene polymorphisms in PE more precisely. Methods: Eligible studies were searched in PubMed, Embase, Web of Science and Chinese (Chinese National Knowledge...
Includes: Supplementary data
Articles
Biosci Rep (2020) 40 (4): BSR20200406.
Published: 09 April 2020
...Qianqian Yu; Jing Zhu; Yong Yao; Chao Sun The complement factor I ( CFI ) gene polymorphisms have been reported to age-related macular degenerative (AMD) risk, nevertheless, above association is not consistent. We investigated a meta-analysis to evaluate the conclusions between CFI polymorphisms...
Includes: Supplementary data
Articles
Biosci Rep (2020) 40 (2): BSR20193623.
Published: 28 February 2020
... is not entirely clear and a lot of possible pathogenic mechanisms have been proposed to explain the etiology of BA, including genetic, inflammatory, environmental and developmental abnormalities. As a transcription factor, USF2 gene rs916145 polymorphism has been shown to be related to the risk of BA. Methods: We...
Articles
Biosci Rep (2019) 39 (9): BSR20181025.
Published: 03 September 2019
...Kangpeng Yan; Kun Wu; Chao Lin; Zhigang Jie Previous studies have identified the prostate stem cell antigen ( PSCA ) gene rs2294008 C > T and rs2976392 G > A polymorphisms to be associated with the risk of gastric cancer, the results of which are inconsistent. The present study aimed...
Articles
Biosci Rep (2019) 39 (7): BSR20181824.
Published: 05 July 2019
... and CD80 rs7628626 C>A SNPs and assessed the potential relationship of these SNPs with hepatocellular carcinoma (HCC) risk. A total of 584 HCC cases and 923 healthy controls were recruited. And SNPscan™ genotyping assay was used to obtain the genotypes of ICOS, CD28 and CD80 polymorphisms. We found...
Articles
Biosci Rep (2019) 39 (6): BSR20191298.
Published: 28 June 2019
... characteristics from non-smoking cancers. Until now, the role of ATM rs189037 in cancer risk stratified by smoking status still remains unclear. To evaluate the association between ATM rs189037 and cancer risk based on smoking status, we performed this meta-analysis by a comprehensive literature search via...
Includes: Supplementary data
Articles
Biosci Rep (2019) 39 (6): BSR20182240.
Published: 28 June 2019
... of LEPR rs1137101 variants with susceptibility of cancer, however, the observed results were controversial. We searched literature on the relationship of LEPR rs1137101 G>A polymorphism with cancer risk by using PubMed and Embase databases, covering all publications up to 14 October 2018. In total, 44...
Includes: Supplementary data
Articles
Biosci Rep (2019) 39 (6): BSR20181936.
Published: 20 June 2019
...Chen Chen; Jing-Ni Liu; Jian-Qiang Zhao; Bao Zang Chronic inflammation plays an important role in lung carcinogenesis. Recently, several studies investigated the association of C-reactive protein (CRP) gene 1846C>T polymorphism and lung cancer (LC) risk, but with conflicting findings...
Articles
Biosci Rep (2019) 39 (6): BSR20190515.
Published: 18 June 2019
...). The median level of TMAO in those patients was significantly lower than in those moderate-to-high stroke patients (4.1 μM [IQR, 2.8–6.2] vs. 9.1 μM [5.1–11.0]; P <0.001). In univariate and multivariable models, the unadjusted risk of moderate-to-high stroke was increased by 31% (odds ratio (OR) = 1.31 [95...
Articles
Biosci Rep (2019) 39 (4): BSR20181915.
Published: 02 April 2019
... controls. The pooled results indicated that ADH1B Arg47His polymorphism is significantly associated with the decreased risk of overall cancer (homozygous model, odds ratio (OR) = 0.62, 95% confidence interval (CI) = 0.49–0.77; heterozygous model, OR = 0.71, 95% CI = 0.60–0.84; recessive model, OR = 0.83...
Articles
Biosci Rep (2019) 39 (3): BSR20181809.
Published: 19 March 2019
... articles with 19 case–control studies and 10389 participants were included. Three FOXP3 polymorphisms and six cancer types were evaluated. While no significant results were observed in overall and breast cancer groups for rs3761548 (A/C) polymorphisms, the pooled data showed an elevated risk of cancer...
Articles
Biosci Rep (2018) 38 (6): BSR20181347.
Published: 14 December 2018
...Xueren Gao; Jianguo Wang Purpose: The association between GRIA1 rs548294 G>A and rs2195450 C>T polymorphisms and migraine risk has been reported in several case–control studies. However, the results of studies are inconsistent. Thus, we conducted a meta-analysis to more precisely estimate...
Includes: Supplementary data
Articles
Biosci Rep (2018) 38 (6): BSR20181642.
Published: 11 December 2018
...Chuan Jiang; Chunli Xie; Jianli Feng; Maolin Hao In the present study, we included currently published evidence to comprehensively evaluate the influence of the rs5498 polymorphism within the ICAM1 (intercellular adhesion molecule 1) gene on the genetic risk of multiple sclerosis. STATA 12.0...
Includes: Supplementary data
Articles
Biosci Rep (2018) 38 (6): BSR20181275.
Published: 07 December 2018
...Yawei Zhao; Shuhua Fang; Kerong Que; Guangli Xu; Heng Zhang; Cong Qi; Nian Yang Background : Urotensin-II (UII) rs228648 polymorphism has been reported to be associated with the risk of diabetes mellitus (DM) with inconsistent results. The present study sought to reassess the relationship between...
Articles
Biosci Rep (2018) 38 (5): BSR20171320.
Published: 17 October 2018
.... Nonetheless, the role of ET-1 ( EDN1 ) gene variants on coronary artery disease (CAD) risk remains poorly understood. The aim of the present study was to evaluate the role of EDN1 gene polymorphisms on individual susceptibility to CAD. We genotyped five tagSNPs (single-nucleotide polymorphisms) (rs6458155...
Includes: Supplementary data
Articles
Biosci Rep (2018) 38 (5): BSR20181071.
Published: 14 September 2018
... with the risk of cervical cancer, yet with conflicting conclusions. To derive a more precise estimation of the relationship, we performed this meta-analysis updated to June 2018. A total of seven original publications were identified covering IL-6 -174G>C (rs1800795) polymorphism. Odds ratios (ORs) and 95...
Articles
Biosci Rep (2018) 38 (5): BSR20171652.
Published: 05 September 2018
... of single nucleotide polymorphisms (SNPs) of lncRNA- H19 gene with the risk and prognosis of HCC. A total of 944 samples composed of 472 HCC patients and 472 matched controls were included in the risk analysis and amongst them 350 HCC samples were investigated in the prognosis analysis. KASP method...
Includes: Supplementary data
Articles
Biosci Rep (2018) 38 (3): BSR20180072.
Published: 27 June 2018
...Jing Wen; Zhi Lv; Hanxi Ding; Xinxin Fang; Mingjun Sun Single nucleotide polymorphisms (SNPs) in miRNA biosynthesis genes DROSHA and DGCR8 were indicated to be correlated with cancer risk. We comprehensively reviewed and analyzed the effect of DROSHA and DGCR8 polymorphisms on cancer risk. Eligible...
Includes: Supplementary data
Articles
Biosci Rep (2018) 38 (3): BSR20171614.
Published: 12 June 2018
...Jing Wen; Zhi Lv; Hanxi Ding; Xinxin Fang; Mingjun Sun Current studies have explored the correlation between the single nucleotide polymorphisms (SNPs) of pregnane X receptor ( PXR ) and cancer risk. However, the findings were conflicting. Hence, we performed a comprehensive review and meta...
Includes: Supplementary data
Articles
Biosci Rep (2017) 37 (5): BSR20170713.
Published: 06 October 2017
...-β (TGF-β) receptor type I and II ( TGFBR1 and TGFBR2 ) gene polymorphisms with the risk of hypospadias in a Chinese population. One hundred and sixty two patients suffering from hypospadias were enrolled as case group and 165 children who underwent circumcision were recruited as control group...
Articles
Biosci Rep (2016) 36 (6): e00404.
Published: 03 November 2016
...Jiantao Wang; Niannian Fan; Yili Deng; Jie Zhu; Jing Mei; Yao Chen; Heng Yang Interleukins (ILs) are the most typical inflammatory and immunoregulatory cytokines. Evidences have shown that polymorphisms in ILs are associated with cerebral infarction risk. However, the results remain inconclusive...