.... Dickey Airway mucin secretion is important pathophysiologically and as a model of polarized epithelial regulated exocytosis. We find the trafficking protein, SNAP23 (23-kDa paralogue of synaptosome-associated protein of 25 kDa), selectively expressed in secretory cells compared with ciliated and basal...

...Guenter Blobel © 2000 Plenum Publishing Corporation 2000 membrane transport protein channel protein targeting secretion signal peptide Bioscience Reports, Vol. 20, No. 5, 2000 NOBEL LECTURE December 8, 1999 Protein Targeting Guenter Blobel1 KEY WORDS: Membrane transport; protein...

... NCIH650 and NCIH2077 (b) provide evidence that these cell lines secrete mucin in culture conditions and (c) investigate the effects of select secretagogues on mucin secretion. The cell lines were established in ACL-4 medium containing several growth factors and retinoic acid and 5% fetal calf serum...

... fluorescence: annular, partly filled and uniformly filled. FM1-43 fluorescence was increased in 61% of the cells by TRH (40 nM), a physiological stimulus for prolactin secretion, and in 89% of the cells by 60 mM external K + . The fluorescence also increased when cells incubated in the presence of quinpirole...

... © 1992 Plenum Publishing Corporation 1992 Electron microscopy secretion neuropeptides exocytosis endocytosis Bioscience Reports, Vol. 12, No. 6, 1992 Exo-Endocytosis in Isolated Peptidergic Nerve Terminals Occurs in the Sub-Second Range Gerd Kno l l , 2'3 He lmut P lat tner , 2 and Jean...

... glycoprotein receptor secretion Bioscience Reports, Vol. 11, No. 1, 1991 Functional and Structural Characterization of the Secretin Receptors in Rat Gastric Glands: Desensitization and Glycoprotein Nature Wafa Bawab, Eric Chastre and Christian Gespach 1 Received Ist version October 1st, 1990; 2nd version...

... calcium. In the case of bradykinin the full rise in ([Ca 2+ ] i ) may involve a component of calcium entry in addition to release of calcium from an internal store. Secretion was also found to be partially independent of external calcium. The different efficacies of the three secretagogues in elicting...

... the nerve terminals, the present paper demonstrates that secretion can occur to the same extent from both nerve endings and nerve swellings. 10 3 1988 © 1988 Plenum Publishing Corporation 1988 exocytosis secretion neuropeptides vasopressin neurohypophysis Bioscience Reports, Vol. 8...

... are easily assayed by radioimmunoassay. Depolarization-induced secretion is dependent on the same parameters as those regulating release from the whole neural lobe. The isolated nerve endings can be permeabilized by means of digitonin; a treatment which gives direct access to the cytoplasm allowing the study...

...+ observed is much smaller than the Ca 2+ needed to trigger secretion when introduced directly into the cell. The discrepancy is removed by the presence of diacylglycerot, which increases the sensitivity of the secretory process to Ca 2+ . The site of action of Ca 2+ and diacylglycerol is probably protein...

... © 1987 Plenum Publishing Corporation 1987 cytoskeleton actin filaments exocytosis secretion chromaffin cells Bioscience Reports, Vol. 7, No. 4, 1987 Fleorganisation of Peripheral Actin Filaments as a Prelude to Exocytosis Robert D. Burgoyne and Timothy R. Cheek Received April 9, 1987...

...Robert L. Dormer; Graham R. Brown; Claire Doughney; Margaret A. McPherson Evidence for a primary role for intracellular Ca 2+ in the stimulation of pancreatic enzyme secretion is reviewed. Measurements of cytoplasmic free Ca 2+ concentration have allowed direct demonstration of its importance...