... the secretion of recombinant proteins into milk in response to a cleavable signal peptide of highly secreted lactoproteins. We previously reported rabbits harboring mammary gland-specific expression vector containing a fusion cDNA (goat β-lactoglobulin (BLG) signal peptide and recombinant human plasminogen...

... receptors) and possesses an N-terminal putative SP (signal peptide). It has been reported that this sequence is required for the synthesis of GLP-1R and is cleaved after receptor synthesis. In the present study, we conducted an in-depth exploration towards the role of the putative SP in GLP-1R synthesis...

...Guenter Blobel © 2000 Plenum Publishing Corporation 2000 membrane transport protein channel protein targeting secretion signal peptide Bioscience Reports, Vol. 20, No. 5, 2000 NOBEL LECTURE December 8, 1999 Protein Targeting Guenter Blobel1 KEY WORDS: Membrane transport; protein...

... on the strong preference of the peptides for negatively charged lipids and the structural consequences thereof, and on preliminary studies of signal peptide-lipid interaction, a role of inverted or concave lipid structures in the process of protein translocation across membranes is suggested. phospholipid...