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Keywords: single nucleotide polymorphisms
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Articles
MiRNA-423 rs6505162 and miRNA-6811 rs2292879 SNP associated with lung cancer in Hainan, China
Open AccessJing Zhou, Chong Meng, Yixuan Li, Yihui Fu, Wenfang Long, Hairong Huang, Yunru Liu, Pengfei Lyu, Sha Xiao
Journal:
Bioscience Reports
Biosci Rep (2023) 43 (9): BSR20231152.
Published: 22 September 2023
... was to examine the impact of eight single-nucleotide polymorphisms (SNPs) in miRNA on the susceptibility to lung cancer (LC) within the Chinese Southern population. Methods: The genotypes of these eight polymorphisms were determined in 132 LC patients and 214 cancer-free controls. Results: In overall analyses...
Articles
PUNISHER rs12318065 C>A transversion: a putative somatic driver mutation for poor prognosis in colon cancer
Open AccessSameerah Shaheen, Eida M. Alshammari, Sara H. Mokhtar, Aliah R. Alshanwani, Eman A. Toraih, Afaf T. Ibrahiem, Manal S. Fawzy, Shymaa Ahmed Maher
Journal:
Bioscience Reports
Biosci Rep (2022) 42 (6): BSR20220465.
Published: 27 June 2022
... BY) . colorectal cancer Prognosis PUNISHER rs12318065 single nucleotide polymorphisms survival The present samples included 138 adenocarcinomas (67.6%), 30 mucinous (14.7%), 26 signet ring cells (12.7%), and 10 undifferentiated (4.9%) carcinoma cases. For all samples, the original hematoxylin...
Articles
Journal:
Bioscience Reports
Biosci Rep (2021) 41 (10): BSR20211338.
Published: 19 October 2021
... access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . association study gestational diabetes mellitus retinoid X receptor single nucleotide polymorphisms susceptibility...
Articles
Journal:
Bioscience Reports
Biosci Rep (2021) 41 (7): BSR20210124.
Published: 26 July 2021
.... The purpose of the present study was to determine the association between four candidate single nucleotide polymorphisms (SNPs) in STAT4 genes and HCC risk in Chinese Han population. Methods: A case–control study was conducted to assess the association between STAT4 SNPs and HCC risk in 1011 Chinese Han...
Articles
Journal:
Bioscience Reports
Biosci Rep (2021) 41 (4): BSR20204136.
Published: 22 April 2021
...Danyang Wang; Qingmin Liu; Yanjun Ren; Yan Zhang; Xin Wang; Bing Liu Background: There is accumulating evidence of aberrant expression of miR-143 and miR-145 and their target gene KRAS in colorectal cancer (CRC). We hypothesize that single nucleotide polymorphisms (SNPs) within or near mRNA...
Includes: Supplementary data
Articles
Journal:
Bioscience Reports
Biosci Rep (2021) 41 (1): BSR20202584.
Published: 14 January 2021
... Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . Allele-specific polymerase chain reaction blood donors ferritin hepcidin single nucleotide polymorphisms Numerous biologic processes rely upon adequate iron levels [ 1 ]. Over the past decade, many...
Includes: Supplementary data
Articles
Journal:
Bioscience Reports
Biosci Rep (2020) 40 (10): BSR20202628.
Published: 28 October 2020
... of CMIP single-nucleotide polymorphisms (SNPs) on dyslipidaemia and clinicopathologic features of IgAN. Clinical and pathological data from patients with IgAN diagnosed at the First Affiliated Hospital of Guangxi Medical University were collected. DNA was extracted from blood samples. CMIP rs2925979...
Articles
Journal:
Bioscience Reports
Biosci Rep (2020) 40 (9): BSR20202102.
Published: 24 September 2020
...Fei Bai; Ke Xiao Background: Gastric cancer (GC) is a complex multifactorial disease. Previous studies have revealed genetic variations associated with the risk of gastric cancer. The purpose of the present study was to determine the correlation between single-nucleotide polymorphisms (SNPs...
Includes: Supplementary data
Articles
MIR17HG polymorphism (rs7318578) is associated with liver cancer risk in the Chinese Han population
Open AccessXu Chao, Xuesong Feng, Hailong Shi, Yuewen Wang, Lanlan Wang, Haiyu Shen, Qing Zha, Yanni Chen, Chao Jiang
Journal:
Bioscience Reports
Biosci Rep (2020) 40 (8): BSR20193312.
Published: 28 August 2020
...Xu Chao; Xuesong Feng; Hailong Shi; Yuewen Wang; Lanlan Wang; Haiyu Shen; Qing Zha; Yanni Chen; Chao Jiang Numerous evidence has revealed that single-nucleotide polymorphisms (SNPs) are associated with liver cancer risk. To assess whether the MIR17HG polymorphisms are associated with the liver...
Articles
Journal:
Bioscience Reports
Biosci Rep (2020) 40 (8): BSR20202072.
Published: 17 August 2020
...Yu-Huei Liu; Chiou-Yuan Shen; Fuu-Jen Tsai The macrophage migration inhibitory factor (MIF)/cluster of differentiation 74 (CD74) plays a role in immunological functions. The present study aims to investigate whether single-nucleotide polymorphisms (SNPs) in the MIF and CD74 are risk factors...
Articles
Journal:
Bioscience Reports
Biosci Rep (2020) 40 (6): BSR20200824.
Published: 25 June 2020
..., IBM SPSS statistics 25 and Stata MP 16.0 software were used to do this meta-analysis. Results: Our meta-analysis involved 2553 PCOS patients and 3152 controls, for two single nucleotide polymorphisms (rs10830963 C> G in MTNR1B and rs2119882 T> C in MTNR1A) and significant associations were found...
Articles
The effect of LTA gene polymorphisms on cancer risk: an updated systematic review and meta- analysis
Open Access
Journal:
Bioscience Reports
Biosci Rep (2020) 40 (5): BSR20192320.
Published: 28 May 2020
... (CC BY) . tumour necrosis factors cancer single nucleotide polymorphisms meta analysis Increasing studies have demonstrated that a number of proinflammatory cytokines could be associated with the development of cancer [ 1 , 2 ]. Lymphotoxin-α (LTA) is the predominant member...
Includes: Supplementary data
Articles
HSPA1L rs1061581 polymorphism is associated with the risk of preeclampsia in Han Chinese women
Open AccessJinbao Zong, Yan Lin, Qingwu Tian, Xin Zhao, Kaiqiu Chu, Bing Jiang, Shengjun Li, Guirong Sun, Shiguo Liu
Journal:
Bioscience Reports
Biosci Rep (2020) 40 (2): BSR20194307.
Published: 28 February 2020
... on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . heat shock proteins gene polymerase chain reaction preeclampsia single nucleotide polymorphisms Pre-eclampsia (PE) is a pregnancy-specific syndrome characterized by de novo...
Articles
The association of TNF-α −308G/A and −238G/A polymorphisms with type 2 diabetes mellitus: a meta-analysis
Open Access
Journal:
Bioscience Reports
Biosci Rep (2019) 39 (12): BSR20191301.
Published: 20 December 2019
... 04 12 2019 05 12 2019 -238G/A -308G/A meta analysis single nucleotide polymorphisms T2DM TNF-α © 2019 The Author(s). 2019 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative...
Articles
Heinz Drexel, Andreas Leiherer, Christoph H. Saely, Eva Maria Brandtner, Kathrin Geiger, Alexander Vonbank, Peter Fraunberger, Axel Muendlein
Journal:
Bioscience Reports
Biosci Rep (2019) 39 (8): BSR20190299.
Published: 07 August 2019
...) with atherosclerotic, cardiovascular disease. So far, a link between common genetic variations of the SGLT2 encoding gene SLC5A2 and glucose homeostasis as well as cardiovascular disease has not been established. The present study, therefore, aimed to investigate SLC5A2 single nucleotide polymorphisms (SNPs...
Includes: Supplementary data
Articles
TNFAIP8L1 and FLT1 polymorphisms alter the susceptibility to cervical cancer amongst uyghur females in China
Open Access
Journal:
Bioscience Reports
Biosci Rep (2019) 39 (7): BSR20191155.
Published: 19 July 2019
... of these two genes and the risk of cervical cancer in the Uygur women. The study involved 342 cervical cancer patients and 498 healthy women. Five single nucleotide polymorphisms (SNPs) from the TNFAIP8L1 gene and the FLT1 gene were selected and genotyped. Odds ratio and 95% CIs were calculated by logistic...
Includes: Supplementary data
Articles
Han Shi, Hongyan He, Suvash Chandra Ojha, Changfeng Sun, Juan Fu, Mao Yan, Cunliang Deng, Yunjian Sheng
Journal:
Bioscience Reports
Biosci Rep (2019) 39 (6): BSR20190783.
Published: 20 June 2019
... infection and HCC. HBV HCC Meta-analysis single nucleotide polymorphisms STAT3 STAT4 Correspondence: Yunjian Sheng ( [email protected] ) 29 03 2019 21 05 2019 30 05 2019 03 06 2019 © 2019 The Author(s). 2019 This is an open access article published...
Includes: Supplementary data
Articles
Journal:
Bioscience Reports
Biosci Rep (2019) 39 (5): BSR20190024.
Published: 14 May 2019
... dose, applied duration, and single-nucleotide polymorphism (SNP). We also conducted a dose-response meta-analysis to analyze the cumulative dosage and SONFH risk in mutation carriers. There were significant correlations between the ABCB1 rs1045642 mutant and SONFH in the prednisone-use...
Includes: Supplementary data
Articles
SNP rs2596542G>A in MICA is associated with risk of hepatocellular carcinoma: a meta-analysis
Open Access
Journal:
Bioscience Reports
Biosci Rep (2019) 39 (5): BSR20181400.
Published: 07 May 2019
...Haichuan Wang; Hui Cao; Zhong Xu; Dong Wang; Yong Zeng The association of major histocompatibility complex class I chain-related gene A ( MICA ) single nucleotide polymorphism (SNP) rs2596542G>A and hepatocellular carcinoma (HCC) has been broadly studied, with inconsistent results. Therefore, we...
Includes: Supplementary data
Articles
Association between polymorphism in the promoter region of lncRNA GAS5 and the risk of colorectal cancer
Open Access
Journal:
Bioscience Reports
Biosci Rep (2019) 39 (4): BSR20190091.
Published: 16 April 2019
... Attribution License 4.0 (CC BY) . colorectal cancer GAS5 large intervening non-coding RNA single nucleotide polymorphisms Colorectal cancer (CRC) is one of the most common types of cancer worldwide, with 1.36 million new cases of CRC and 694000 deaths in 2012 [ 1 ]. The current evidence...
Articles
Journal:
Bioscience Reports
Biosci Rep (2019) 39 (4): BSR20180723.
Published: 16 April 2019
... in microRNAs (miRNAs/miRs) play an important role in the susceptibility of various types of cancers. Objective: To evaluate the association of Single Nucleotide Polymorphisms (SNPs) in miR-146a (rs2910164), miR-196a2 (rs11614913), and miR-499 (rs3746444), with cervical cancer susceptibility in Indian...
Includes: Supplementary data
Articles
Association between ADIPOQ gene variants and knee osteoarthritis in a Chinese population
Open Access
Journal:
Bioscience Reports
Biosci Rep (2019) 39 (3): BSR20182104.
Published: 01 March 2019
... published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . ADIPOQ knee osteoarthritis single nucleotide polymorphisms Osteoarthritis (OA) is a clinical syndrome of joint pain and dysfunction...
Articles
Association of matrix Gla protein polymorphism and knee osteoarthritis in a chinese population
Open Access
Journal:
Bioscience Reports
Biosci Rep (2019) 39 (1): BSR20182228.
Published: 25 January 2019
... single nucleotide polymorphisms Osteoarthritis (OA), is the most prevalent type of arthritis and main reason for the chronic disability of the elderly [ 1 ]. According to the WHO, at least 10% of people aged ≥ 60 years old worldwide suffer from OA, characterized by joint stiffness, limitation...
Articles
Journal:
Bioscience Reports
Biosci Rep (2019) 39 (1): BSR20180789.
Published: 18 January 2019
... effect. The discovery of GAS5 and in-depth study of single nucleotide polymorphism (SNP) mechanism can provide a new way for the prevention and treatment of digestive system tumors. Hepatocarcinoma is one of the most common tumors in digestive system tumors, and GAS5 plays an important role in hepatic...
Articles
Journal:
Bioscience Reports
Biosci Rep (2019) 39 (1): BSR20181770.
Published: 15 January 2019
... leukaemia methionine synthase meta analysis single nucleotide polymorphisms susceptibility Acute lymphoblastic leukemia (ALL) is the most common childhood cancer, which accounts for 30% of all malignancy diagnosed in children and 80% of pediatric leukemia [ 1 ]. However, the etiology...
Articles
Journal:
Bioscience Reports
Biosci Rep (2018) 38 (6): BSR20181619.
Published: 30 November 2018
... the association of other single nucleotide polymorphisms and musculoskeletal degenerative diseases. The leave-one-out sensitivity analysis was performed by omitting each study in turn and re-evaluating the resulting effect on the overall effect. Egger’s regression test and Begg’s rank correlation test were used...
Articles
No association between HMGB1 polymorphisms and cancer risk: evidence from a meta-analysis
Open AccessXing-yan Li, Chun-hua Liang, Ye-jing Yang, Lei Liu, Yong-jun Du, Hong-suo Liang, Lin Li, Bo Zhang, Jian-min Li, Jin-min Zhao
Journal:
Bioscience Reports
Biosci Rep (2018) 38 (5): BSR20180658.
Published: 05 September 2018
... the Creative Commons Attribution License 4.0 (CC BY) . cancer High mobility group box 1 meta analysis single nucleotide polymorphisms High mobility group box 1 (HMGB1), also known as HMG1 [ 1 ], is a highly conserved, ubiquitously expressed single polypeptide in all mammalian eukaryotic cells...
Articles
Journal:
Bioscience Reports
Biosci Rep (2018) 38 (3): BSR20180072.
Published: 27 June 2018
...Jing Wen; Zhi Lv; Hanxi Ding; Xinxin Fang; Mingjun Sun Single nucleotide polymorphisms (SNPs) in miRNA biosynthesis genes DROSHA and DGCR8 were indicated to be correlated with cancer risk. We comprehensively reviewed and analyzed the effect of DROSHA and DGCR8 polymorphisms on cancer risk. Eligible...
Includes: Supplementary data
Articles
Shi-Qi Huang, Zi-Xing Zhou, Shao-Ling Zheng, Dan-Dan Liu, Xiao-Hong Ye, Cheng-Li Zeng, Ya-Jing Han, Zi-Hao Wen, Xiao-Qian Zou, Jing Wu, Yu-Mei Liu, Chui-Can Huang, Yao Wang, Guang Yang, Chun-Xia Jing
Journal:
Bioscience Reports
Biosci Rep (2018) 38 (3): BSR20171565.
Published: 31 May 2018
..., and their genetic variants are involved in the development of various cancers. Our study aimed to determine the potential association between miRNA processing gene polymorphisms and cervical precancerous lesions. Five single nucleotide polymorphisms (SNPs), including Ran-GTP ( RAN ) rs14035, exportin-5 ( XPO5...
Includes: Supplementary data
Articles
Correlations between ACE single nucleotide polymorphisms and prognosis of patients with septic shock
Open Access
Journal:
Bioscience Reports
Biosci Rep (2017) 37 (2): BSR20170145.
Published: 28 April 2017
...Xin-Man Dou; Hui-Juan Cheng; Ling Meng; Lin-Lin Zhou; Yi-Hong Ke; Li-Ping Liu; Yu-Min Li The aim of the present study is to investigate association between septic shock (SS) and angiotensin I-converting enzyme ( ACE ) single nucleotide polymorphisms (SNPs). From October 2009 to December 2016, 238...
