... indicate the RII tetra-tandemer is significantly rigidified upon Ca 2+ binding, and that the protein's solution structure is in excellent agreement with its crystal structure. We hypothesize that >600 Ca 2+ help rigidify the chain of ~120 104-residue repeats to form a ~0.6 μm rod-like structure in order...

... stabilized α-helical and β-sheet motif functional dyad ryanodine receptor scorpion toxin solution structure voltage-gated ion channel In this work, we describe a new scorpion ICK peptide, named λ-MeuKTx-1 (abbreviated as λ-MK1) that is designated as the first member of the λ-KTx family coming from...