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Keywords: thapsigargin
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Articles

The 78 kDa Glucose-Regulated Protein (GRP78/BIP) Is Expressed on the Cell Membrane, Is Released into Cell Culture Medium and Is Also Present in Human Peripheral Circulation

Andrea Delpino, Mauro Castelli
Journal: Bioscience Reports
Biosci Rep (2002) 22 (3-4): 407–420.
https://doi.org/10.1023/A:1020966008615
Published: 01 August 2002
...Andrea Delpino; Mauro Castelli In human rabdomiosarcoma cells (TE671/RD) chronic exposure to 500 nM thapsigargin (a powerful inhibitor of the endoplasmic reticulum Ca 2+ -ATPases) resulted in the induction of the stress protein GRP78/BIP. Making use of the surface biotinylation method, followed...
View article titled, The 78 kDa Glucose-Regulated Protein (GRP78/BIP) Is Expressed on the Cell Membrane, Is Released into Cell Culture Medium and Is Also Present in Human Peripheral Circulation
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Articles

Inhibition of the Ecto-ATPdiphosphohydrolase of Schistosoma mansoni by Thapsigargin

Samantha M. Martins, Christiane R. Torres, Sérgio T. Ferreira
Journal: Bioscience Reports
Biosci Rep (2000) 20 (5): 369–381.
https://doi.org/10.1023/A:1010330017583
Published: 01 October 2000
... the effectsof thapsigargin, a sesquiterpene lactone known as a high affinityinhibitor of sarco-endoplasmic reticulum calcium transport (SERCA)ATPase, on ATPDase activity. Whereas other lactones tested had littleor no inhibitory action, thapsigargin inhibited ATP hydrolysis by the ATPDase ( K i ∼20 μM...
View article titled, Inhibition of the Ecto-ATPdiphosphohydrolase of Schistosoma mansoni by <span class="search-highlight">Thapsigargin</span>
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Articles

Use of thapsigargin to study Ca 2+ homeostasis in cardiac cells

Terry B. Rogers, Giuseppe Inesi, Robert Wade, W. J. Lederer
Journal: Bioscience Reports
Biosci Rep (1995) 15 (5): 341–349.
https://doi.org/10.1007/BF01788366
Published: 01 October 1995
...Terry B. Rogers; Giuseppe Inesi; Robert Wade; W. J. Lederer Several reports have documented that thapsigargin is a potent inhibitor of the SR Ca 2+ ATPase isolated from cardiac or skeletal muscle. We have characterized the specificity of this agent in intact rat cardiac myocytes using cells...
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