... skeletal muscle thermogenesis The Editorial Office has been made aware of potential issues surrounding the scientific validity of this paper, hence has issued an expression of concern to notify readers whilst the Editorial Office investigates. ...

..., fibrosis, and insulin resistance. This review focuses on recent advances in our understanding of the identity of ASCs and their roles in adipose tissue development, homeostasis, expansion, and thermogenesis, and how these roles go awry in obesity. A better understanding of the biology of ASCs...

... and distributed under the Creative Commons Attribution License 4.0 (CC BY) . adipocyte adipogenesis stages of differentiation TGFβ thermogenesis Along with its known fibrogenic activity, TGFβ is a critical cytokine mediator of both insulin resistance and hepatic steatosis in obesity-induced...

... metabolism is the molecular basis of heat generation, while it serves only a secondary role in supplying energy for thermogenesis in muscle. Here, we wanted to document changes in mitochondrial ultrastructure in these two tissue types based upon adaptation to mild (16°C) and severe (4°C) cold in mice. When...

...Leopoldo De Meis; Luisa A. Ketzer; Juliana Camacho-Pereira; Antonio Galina The UCP1 [first UCP (uncoupling protein)] that is found in the mitochondria of brown adipocytes [BAT (brown adipose tissue)] regulates the heat production, a process linked to non-shivering thermogenesis. The activity...

...María del Mar Romero; José A. Fernández-López; Montserrat Esteve; Marià Alemany In the present study we intended to determine how BAT (brown adipose tissue) maintained thermogenesis under treatment with OE (oleoyl-oestrone), a powerful slimming hormone that sheds off body lipid but maintains...

...Julien Mozo; Yalin Emre; Frederic Bouillaud; Daniel Ricquier; Francois Criscuolo Mammals and birds are endotherms and respond to cold exposure by the means of regulatory thermogenesis, either shivering or non-shivering. In this latter case, waste of cell energy as heat can be achieved by uncoupling...

... medium as heat. The thyroid hormone 3,5,3′-triiodo l -thyronine (T 3 ) regulates the expression and function of the thermogenic SERCA isoforms. Modulation of heat production by SERCA might be one of the mechanisms involved in the increased thermogenesis found in hyperthyroidism. © 2005 Springer Science...

... with the control and regulatory mechanisms governing thermogenesis. High core temperatures are essential for animal flight irrespective of the taxa they belong to. Birds and insects have thus evolved mechanisms which allowed them to control and regulate high rates of heat fluxes. This article discusses possible...

...-prototype. UCP1 plays its biological role mainly in the non-shivering thermogenesis while the role of the other types is unknown. However, hypotheses have suggested that they are involved in the general balance of basic energy expenditure, protection from reactive oxygen species, and, in plants, in fruit...

...José Eduardo P. W. Bicudo; Cláudia R. Vianna; José Guilherme Chaui-Berlinck The article discusses the importance of avian skeletal muscle as a source for heat generation by means of both shivering and non-shivering. Non-shivering thermogenesis in birds is still a polemic issue. Recent evidence...

... species and in different thyroid states. Such differences imply some function for proton leak and candidates for this function include thermogenesis, protection against reactive oxygen species, endowment of metabolic sensitivity and maintenance of carbon fluxes. Mitochondria proton leak Standard...

..., but not prevented, by surgical denervation of the tissue, and was unaffected by pretreatment with α-helical CRF 9–41. These data indicate that TNFα can stimulate thermogenesis by a direct central action. The effects are largely, but not totally, dependent on the sympathetic nervous system but, unlike...

... with TNF treatment and with cancer cachexia. 26 10 1987 © 1987 Plenum Publishing Corporation 1987 tumour necrosing factor brown fat thermogenesis GDP-binding food intake body weight rats Bioscience Reports, VoI. 7, No. 10, 1987 Changes in Thermogenesis and Brown Fat Activity...

... the in vivo content determined from freeze clamped tissue. © 1986 Plenum Publishing Corporation 1986 11 8 1987 rat brown adipocytes brown adipose tissue oxygen consumption ATP content DNA content norepinephrine thermogenesis Bioscience Reports, Vol. 7, No. 8, 1987 Metabolic...

...-adrenoceptor agonist BRL 26830A. However, ciglitazone was not itself thermogenic after an acute dose, nor did it raise resting metabolic rate during chronic dietary dosing. 29 6 1987 © 1987 Plenum Publishing Corporation 1987 ciglitazone thermogenesis brown adipose tissue GDP binding mice...

... that serotonergic synapses might play a regulatory role in the sympathetic control of BAT thermogenesis and in the rate of WAT deposition (by an as yet unidentified mechanism), in addition to their well established role in controlling food intake. 10 3 1987 © 1987 Plenum Publishing Corporation 1987...

...Nancy J. Rothwell; Michael J. Stock 29 11 1985 © 1986 Plenum Publishing Corporation 1986 brown adipose tissue thermogenesis cold diet neural control hormonal control Biosciqnce Reports, Vol. 6, No. 1, 1986 Review Whither Brown Fat? Nancy J. Rothwell 1 and Michael J. Stock...