... made to characterize the surfaceome of patients with breast cancer, particularly in relation with the current molecular breast cancer (BRCA) classification. In this view, we developed a new computational method to infer cell-surface protein activities from transcriptomics data, termed ‘SURFACER...

..., and LC-MS/MS analysis were performed to detect metabolites of GC and PC tissues. Metabolite pathways based on differential metabolites were enriched by MetaboAnalyst, and genes related to metabolite pathways were identified using the KEGGREST function of the R software package. Transcriptomics data from...

... targeting strategies for these chemokines to prevent tumor growth will improve both prognosis and therapeutic outcomes. bioinformatics biomarkers breast cancers chemokines immunology transcriptomics The study performed by Chen et al. represents a comprehensive analysis of CCL-type chemokines...

... effector proteins (CSEPs) that are used by the pathogen to support infection and control disease development. We generated de novo assembled transcriptomes of Pst collected from wheat fields in central Anatolia. We inoculated both susceptible and resistant seedlings with Pst and analyzed haustoria...

... the Creative Commons Attribution License 4.0 (CC BY) . Bioinformatics Computational biology Pulmonary Arterial Hypertension Transcriptomics Pulmonary arterial hypertension (PAH) is a common disorder worldwide characterized by irreversible remodeling of the distal pulmonary arteries...

... in lung tissues of COPD rats. We also investigated therapeutic effects of aminophylline (APL) on the COPD rats and integrated transcriptome, proteome, and metabolome data for a global view of molecular mechanisms of COPD progression. Using molecular function and pathway analyses, the genes and proteins...