... <0.05 was considered to be statistically significant. For correlation analyzes, Pearson’s test was performed. chloride hypertension intracellular signaling molecular basis of health and disease renal physiology transport Hypertension is a major worldwide public health problem...

... differences accompanying ligand binding. Such conformational changes may regulate fruitful engagement of the cognate ABC (ATP-binding cassette) transporter system (SitBC) required for metal uptake. These results provide the first detailed characterization and mechanistic insights for a potential therapeutic...

... the development of livertumor. The possible mechanisms of low protein diet induced inhibition ofSERCA activity are highlighted. ATPase calcium liver protein malnutrition transport tumor © 2000 Plenum Publishing Corporation 2000 Bioscience Reports, Vol. 20, No. 2, 2000 The Ca2+-Transporting...

...Stephen A. Baldwin; L. Felipe Barros; Mark Griffiths The uptake of glucose into mammalian cells, catalysed by members of the GLUT family of glucose transporters, is regulated by a variety of hormones, growth factors and other agents. In adipocytes, skeletal muscle and heart the principal regulator...

...William P. Jencks The coupling of the chemical reaction of ATP hydrolysis to the transport of calcium from the cytoplasm into the lumen of sarcoplasmic reticulum vesicles can be defined by a set of rules that define alternating changes in the specificities of the enzyme for catalysis of chemical...

...A. Rodríguez-Martín; N. Bel; X. Remesar A density gradient method is used to isolate membrane vesicles from brown adipose tissue. These respond to changes in osmolarity and show the classical overshoot pattern when L-alanine uptake is assayed. Transport is shown to be effected by two components...

...Peter B. Garland The concept of chemiosmotic systems arises from the pioneering work of Peter Mitchell on two fronts. One is concerned with the mechanisms by which molecules are transported across membranes which are generally barriers to such transport. These mechanisms are inevitably molecular...

...A. Rodríguez-Martín; X. Remesar The pattern of L-alanine uptake in isolated cells of interscapular brown adipose tissue has been determined. The uptake can be divided into the diffusion component ( Kd =0.55 min −1 ) and a saturable Na + -dependent transport ( K M =0.87 mM and V max =155 nmol/min/10...

...M. J. A. Ewadh; N. Tudball; F. A. Rose The uptake of L-cystine into cultured human umbilical vein endothelial cells has been shown to occur by a Na + -independent system which is inhibited by L-glutamate and L-homocysteine, but not by other amino acids. It is likely that the system transporting L...