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Keywords: tumorigenesis
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Biosci Rep (2021) 41 (6): BSR-2018-0776_RET.
Published: 08 June 2021
... © 2021 The Author(s). 2021 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . MiR-140-5p retinoblastoma tumorigenesis This Retraction follows...
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Biosci Rep (2020) 40 (8): BSR-20180776_EOC.
Published: 21 August 2020
... © 2020 The Author(s). 2020 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . c-Met/AKT/mTOR signaling pathway MiR-140-5p retinoblastoma tumorigenesis...
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Biosci Rep (2019) 39 (10): BSR20192274.
Published: 18 October 2019
... non-coding RNAs (lncRNAs) participate in cancer tumorigenesis. LncRNA P73 antisense RNA 1T (TP73-AS1), also known as KIAA0495 and p53-dependent apoptosis modulator (PDAM), is located in human chromosomal band 1p36.32 and plays a crucial role in many different carcinomas. This review summarizes current...
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Biosci Rep (2019) 39 (9): BSR20190489.
Published: 03 September 2019
... tumorigenesis. We validated that LUCAT1 induced tumorigenesis and metastasis of TNBC via miR-5702, which provided clues for improving the treatment of TNBC. 5′-GTGCAGGGT CCGAGGT-3′ (antisense); U6: 5′-CTCGCTTCGGCAGCACA-3′ (sense), 5′-AACGCTTCACGAATTTGCGT-3′ (antisense); GAPDH: 5′-GTCAA CGG...
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Biosci Rep (2019) 39 (8): BSR20191815.
Published: 02 August 2019
...Dan Li; Zhenguo Zeng Better understanding of epigenetic regulation of hepatocellular carcinoma (HCC) will help us to cure this most common malignant liver cancer worldwide. The underlying mechanisms of HCC tumorigenesis are genomic aberrations regulated by genetic and epigenetic modifications...
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Articles
Biosci Rep (2019) 39 (3): BSR20182351.
Published: 01 March 2019
... the activity of ERK2 and promote the tumorigenesis of colorectal cancer HCT15 cells. Clinical simple showed that STK33 was highly expression in colorectal cells and tissues. Ex vivo and in vivo studies demonstrated that STK33 accelerate tumorigenic properties in NCM460 cells and athymic nude rats. In vitro...
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Biosci Rep (2018) 38 (6): BSR20181386.
Published: 14 December 2018
... © 2018 The Author(s). 2018 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . colorectal cancer large intervening non-coding RNA microRNA tumorigenesis...
Articles
Biosci Rep (2018) 38 (6): BSR20180776.
Published: 30 November 2018
... to investigate whether miRNAs expression are associated with RB tumorigenesis in RB tissues. We found that a large set of miRNAs were ectopic expressions and miR-140-5p is most significantly down-regulated in human RB tissues compared with normal retinas. In addition, low miR-140-5p expression is associated...
Articles
Biosci Rep (2013) 33 (4): e00050.
Published: 16 July 2013
... p27 Kip1 directly. Interestingly, the lack of phosphorylation at Ser 158 of the β1 subunit promotes degradation of p27 Kip1 . We therefore propose that the β1 subunit plays a novel role in tumorigenesis by degrading p27 Kip1 . 1 Correspondence may be addressed to either of these authors (email...
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Biosci Rep (2012) 32 (1): 25–33.
Published: 26 September 2011
... confer cross-resistance to PLX4720 [ 60 ]. © The Authors Journal compilation © 2012 Biochemical Society 2012 BRAF inhibitor combination therapy mitogen-activated protein kinase melanoma tumorigenesis Melanoma is a major form of skin cancer and arises from malignant transformation...
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Articles
Biosci Rep (2010) 30 (5): 285–291.
Published: 09 April 2010
... by androgen signalling and paracrine factors are essential for gland organogenesis, homoeostasis and tumorigenesis. FGFs mediate these mesenchymal–epithelial interactions in the prostate by paracrinal crosstalk through a diverse set of ligands and receptors. Gain- and loss-of-function studies in mouse models...