Ageing and disease states associated with an increase in cardiovascular events alter the physical characteristics of blood vessel walls and impair the pulsatile function of arteries. An accumulating body of evidence indicates that impaired pulsatile function of arteries provides important prognostic and therapeutic information beyond that provided by traditional blood pressure measurements. A variety of techniques are currently employed to evaluate the mechanical properties of arteries. All techniques have theoretical, technical and practical limitations that impact on their widespread application in the clinical setting and use as measurement tools to improve cardiovascular risk stratification. A detailed discussion of these issues forms the basis of this review.
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Review Article|
December 10 2001
Evaluation of mechanical arterial properties: clinical, experimental and therapeutic aspects
Gary E. MCVEIGH;
1Department of Therapeutics and Pharmacology, Whitla Medical Building, Queen's University Belfast, 97 Lisburn Road, Belfast BT9 7BL, Northern Ireland, U.K.
Correspondence: Dr G. E. McVeigh (e-mail [email protected]).
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Paul K. HAMILTON;
Paul K. HAMILTON
1Department of Therapeutics and Pharmacology, Whitla Medical Building, Queen's University Belfast, 97 Lisburn Road, Belfast BT9 7BL, Northern Ireland, U.K.
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David R. MORGAN
David R. MORGAN
1Department of Therapeutics and Pharmacology, Whitla Medical Building, Queen's University Belfast, 97 Lisburn Road, Belfast BT9 7BL, Northern Ireland, U.K.
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Publisher: Portland Press Ltd
Online ISSN: 1470-8736
Print ISSN: 0143-5221
The Biochemical Society and the Medical Research Society © 2002
2002
Clin Sci (Lond) (2002) 102 (1): 51–67.
Citation
Gary E. MCVEIGH, Paul K. HAMILTON, David R. MORGAN; Evaluation of mechanical arterial properties: clinical, experimental and therapeutic aspects. Clin Sci (Lond) 1 January 2002; 102 (1): 51–67. doi: https://doi.org/10.1042/cs1020051
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