Inhibition of Apoptosis of Activated Hepatic Stellate Cells by Timp-1 is Mediated via Effects on Mmp Inhibition: Implications for Reversibility of Liver Fibrosis

Murphy, F.; Issa, R.; Zhou, X.; Hussain, H.; Ratnarajah, S.; Soloway, P.; Nagase, H.; Mjp, Arthur; Benyon, RC; Iredale, JP

doi:10.1042/cs103040P

F. Murphy;

F. Murphy

1Liver Group, Division of Infection, Inflammation & Repair, Southampton University, Southampton, SO16 6YD

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R. Issa;

R. Issa

1Liver Group, Division of Infection, Inflammation & Repair, Southampton University, Southampton, SO16 6YD

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X. Zhou;

X. Zhou

1Liver Group, Division of Infection, Inflammation & Repair, Southampton University, Southampton, SO16 6YD

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H. Hussain;

H. Hussain

1Liver Group, Division of Infection, Inflammation & Repair, Southampton University, Southampton, SO16 6YD

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S. Ratnarajah;

S. Ratnarajah

1Liver Group, Division of Infection, Inflammation & Repair, Southampton University, Southampton, SO16 6YD

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P. Soloway;

P. Soloway

¹Rosewell Park Cancer Institute, New York, USA

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H. Nagase;

H. Nagase

² The Kennedy Institute, Imperial College, London, UK

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Arthur Mjp;

Arthur Mjp

1Liver Group, Division of Infection, Inflammation & Repair, Southampton University, Southampton, SO16 6YD

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RC Benyon;

RC Benyon

1Liver Group, Division of Infection, Inflammation & Repair, Southampton University, Southampton, SO16 6YD

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JP Iredale

1Liver Group, Division of Infection, Inflammation & Repair, Southampton University, Southampton, SO16 6YD

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Inhibition of Apoptosis of Activated Hepatic Stellate Cells by Timp-1 is Mediated via Effects on Mmp Inhibition: Implications for Reversibility of Liver Fibrosis

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Inhibition of Apoptosis of Activated Hepatic Stellate Cells by Timp-1 is Mediated via Effects on Mmp Inhibition: Implications for Reversibility of Liver Fibrosis

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