The Leukaemia-Associated AML1-ETO Fusion Protein Acts as a Sequence Specific Transcriptional Repressor in vivo by Altering the Chromatin Structure of Target Genes

Follows, George A.; Tagoh, Hiromi; Lefevre, Pascal; Morgan, Gareth J.; Bonifer, Constanze

doi:10.1042/cs104030P

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Conference Abstract| April 01 2003

The Leukaemia-Associated AML1-ETO Fusion Protein Acts as a Sequence Specific Transcriptional Repressor in vivo by Altering the Chromatin Structure of Target Genes

George A. Follows;

George A. Follows

¹ Molecular Medicine Unit, University of Leeds, St James's University Hospital, Leeds LS9 7TF, UK

² Academic Unit of Haematology and Oncology, University of Leeds, Leeds General Infirmary Leeds LS1 3EX, UK

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Hiromi Tagoh;

Hiromi Tagoh

¹ Molecular Medicine Unit, University of Leeds, St James's University Hospital, Leeds LS9 7TF, UK

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Pascal Lefevre;

Pascal Lefevre

¹ Molecular Medicine Unit, University of Leeds, St James's University Hospital, Leeds LS9 7TF, UK

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Gareth J. Morgan;

Gareth J. Morgan

² Academic Unit of Haematology and Oncology, University of Leeds, Leeds General Infirmary Leeds LS1 3EX, UK

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Constanze Bonifer

¹ Molecular Medicine Unit, University of Leeds, St James's University Hospital, Leeds LS9 7TF, UK

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Author and article information

Publisher: Portland Press Ltd

Online ISSN: 1470-8736

Print ISSN: 0143-5221

2003

Clin Sci (Lond) (2003) 104 (s49): 30P.

https://doi.org/10.1042/cs104030P

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The Leukaemia-Associated AML1-ETO Fusion Protein Acts as a Sequence Specific Transcriptional Repressor in vivo by Altering the Chromatin Structure of Target Genes