We recently published an original research article in Clinical Science reporting that the age-associated impairment in brachial artery FMD (flow-mediated dilation), a non-invasive measure of conduit artery endothelial function, was exacerbated in MA/O (middle-aged and older) adults with IFG (impaired fasting plasma glucose) concentrations, but this was not observed in MA/O adults with IFG who perform regular aerobic exercise [1]. This paper was the latest report in an extensive series of studies performed by our laboratory over the last decade investigating the effects of aging on vascular endothelial function in humans, the modulatory influences involved and the underlying mechanisms [2]. Several of the articles in this series have reported results on brachial artery FMD among different groups of young and MA/O healthy adults, as was the case in the present study [1].

After the...

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