The IMPC (International Mouse Phenotyping Consortium) was launched recently, and its aim is to develop and phenotype mouse knockouts of 4000 genes over the next 5 years and, ultimately, of all 20000 or so genes in the mouse genome. As part of the IMPC, the MRC (Medical Research Council) also launched a call for MRC mouse networks, where groups of U.K.-based researchers could form a consortium based around a particular area of research. Members of the respiratory research community formed the RDDRC (Respiratory Development and Disease Research Consortium) to consolidate and develop respiratory phenotyping methods suitable for high-throughput screening. This paper, arising from a Biochemical Society workshop held in London in 2012, highlights the purposes of the RDDRC and the needs of the respiratory research community.
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Conference Article|
July 16 2013
Delivering and phenotyping mouse models for the respiratory community: a report on the Biochemical Society Workshop
Charlotte Dean;
Charlotte Dean
1
*Leukocyte Biology, National Heart and Lung Institute, Imperial College London, U.K.
†Mammalian Genetics Unit, Medical Research Council, Harwell, U.K.
Correspondence: Dr Charlotte Dean (email c.dean@imperial.ac.uk) or Dr Matthew Hind (email M.Hind@rbht.nhs.uk).
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Colin Bingle;
Colin Bingle
‡Academic Unit of Respiratory Medicine, Department of Infection and Immunity, University of Sheffield, Sheffield, U.K.
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Matthew Hind
Matthew Hind
1
§Adult Intensive Care Unit, Royal Brompton and Harefield NHS Foundation Trust, London, U.K.
Correspondence: Dr Charlotte Dean (email c.dean@imperial.ac.uk) or Dr Matthew Hind (email M.Hind@rbht.nhs.uk).
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Clin Sci (Lond) (2013) 125 (10): 495–500.
Article history
Received:
June 05 2013
Accepted:
June 05 2013
Citation
Charlotte Dean, Colin Bingle, Matthew Hind; Delivering and phenotyping mouse models for the respiratory community: a report on the Biochemical Society Workshop. Clin Sci (Lond) 1 November 2013; 125 (10): 495–500. doi: https://doi.org/10.1042/CS20130274
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