Epidermal growth factor receptor inhibitor protects against abdominal aortic aneurysm in a mouse model

Inhibition of epidermal growth factor receptor (EGFR) activation protected mice from abdominal aortic aneurysm (AAA), which is probably due to suppression of vascular endoplasmic reticulum (ER) stress. Since the signal was confirmed in humans, EGFR may provide a novel therapeutic target for aortic aneurysm.