Abstract
Using changes in tissue [Na+] concentration alone as done with Na+ MRI may not accurately quantitate excess tissue Na+, particularly in cellular tissues. However, individually quantitating alterations in tissue Na+ and water content as possible with ashing studies may still accurately quantitate excess tissue Na+ in these situations. Furthermore, when tissue [Na+] exceeds plasma [Na+], excess tissue Na+ must be present.
© 2019 The Author(s). Published by Portland Press Limited on behalf of the Biochemical Society
2019
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