1. Simultaneous CO2 titration curves of arterial and mixed venous blood were determined in both dog and man in vivo.

2. The slopes of the CO2 titration curves of mixed venous blood were significantly less than those of the corresponding arterial curves.

3. The non-respiratory pH values of the CO2 titration curves of mixed venous blood were significantly greater than those of the corresponding arterial curves.

4. The theoretical explanations of these differences have been discussed.

Keywords:
carbon dioxide titration curves, mixed venous blood
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© 1972 The Biochemical Society and the Medical Research Society
1972
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