1. Pontine stimulation induces a significant increase in renal venous renin activity, in venous-arterial renin activity difference and in renin release from an intact, innervated kidney, whereas no changes are observed in the contralateral denervated kidney. Renal blood flow markedly decreases in the innervated, and remains unchanged in the denervated, kidney during pontine stimulation.
2. Blockade of the vasomotor response to pontine stimulation in one kidney by close arterial infusion of phenoxybenzamine does not reduce the renin released by that kidney as compared with the contralateral intact one.