1. Experimental hypertension could be induced in rats by injecting angiotensin I or II subcutaneously.

2. Such hypertension lasted for about 1 h after injection.

3. Angiotensin-induced hypertension was enhanced and sustained by salt loading and diminished by salt restriction or spironolactone.

4. Angiotensin-salt hypertension is reversed by transplants of compatible renal medulla subcutaneously.

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