1. In seventeen patients with untreated essential hypertension the sodium and water contents of leucocytes were significantly increased, whereas the rate constant for ouabain-sensitive sodium efflux was significantly reduced.
2. These abnormalities were not found in fourteen other patients with well-controlled hypertension.
3. Preliminary observations in accelerated hypertension suggest a different pattern of abnormality in leucocyte sodium metabolism.
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© 1975 The Biochemical Society and the Medical Research Society
1975
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