1. Foetal rat hemi-calvaria were incubated in organ culture with sera from patients with active rheumatoid arthritis.

2. Increased 45Ca resorption was produced by sera from patients who were hypercalcaemic.

3. This bone-resorbing effect could be inhibited by calcitonin.

Keywords:
bone, calcitonin, calcium, hypercalcaemia, rheumatoid arthritis
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© 1976 The Biochemical Society and the Medical Research Society
1976
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