1. Renal hypertensive rats with a normal or suppressed activity of the renin—angiotensin system develop vascular lesions which are similar to those observed in spontaneously hypertensive rats on high sodium diet.
2. Exposure of a vascular bed to high blood pressure results in a rapid damage of the vascular wall, irrespective of the state of the renin—angiotensin system.
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© 1976 The Biochemical Society and the Medical Research Society
1976
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