1. Ouabain-sensitive uptake of 86Rb, a measure of the Na+—K+ pump activity, was studied in tail arteries of rats made hypertensive with deoxycorticosterone and saline.

2. Decreased activity of the ouabain-sensitive Na+—K+ pump supports the hypothesis that the activity of Na+—K+ pump is suppressed in volume-expanded hypertension.

Keywords:
dexamethasone-hypertension, deoxycorticosterone-hypertension, hypertension, Na+—K+pump
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© 1978 The Biochemical Society and the Medical Research Society
1978
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