1. Rats genetically sensitive to salt-induced hypertension showed higher levels of plasma noradrenaline and adrenaline than rats genetically resistant to hypertension.

2. The hypertension-sensitive rats had higher hypothalamic noradrenaline and lower adrenaline than resistant rats.

3. In response to a high salt diet brain-stem noradrenaline increased in sensitive rats and resistant rats exhibited a decrease on the same diet.

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