1. Measurements have been made of whole-body and skeletal muscle protein synthesis in fed and fasted adults with l-[1-13C]leucine.

2. The marked increase in whole-body synthesis on feeding largely reflects the changes in protein synthesis in muscle, which doubles on feeding, compared with a 40% increase in that of the rest of the body.

3. Skeletal muscle in fed man contributes more than half to total protein synthesis occurring in the whole body.

This content is only available as a PDF.
You do not currently have access to this content.