1. Aldosterone given acutely to male Wistar rats stimulated ouabain-sensitive and ouabain-insensitive 22Na efflux from tail arteries.
2. These effects of aldosterone seem to depend on the activation of specific mineralocorticoid receptors, as they are blocked by antimineralo-corticoid drugs.
3. The results suggest that aldosterone may have a physiological role in the control of vascular tone.
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© 1982 The Biochemical Society and the Medical Research Society
1982
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