1. The effect of a high sodium intake on the endogenous digitalis-like activity of several tissues was determined, after extraction, by digoxin radioimmunoassay in rats.

2. The high sodium intake increased the digitalis-like activity in serum but not in adrenals, brain or heart.

Keywords:
digitalis-like material, sodium intake, tissue distribution
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© 1984 The Biochemical Society and the Medical Research Society
1984
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