1. A ouabain-displacing factor (ODF) was measured in the urine of non-pregnant, normotensive pregnant and hypertensive pregnant women by a receptor-binding assay with sodium, potassium-dependent adenosine triphosphatase.

2. Urinary ODF was significantly increased in normal pregnancy.

3. Greater increases were seen in pregnancy-induced hypertension and pre-eclampsia.

Keywords:
ouabain-displacing factor, pre-eclampsia, pregnancy, pregnancy-induced hypertension
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© 1970 The Biochemical Society and the Medical Research Society
1970
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