Diabetes, Fructosamine and Free Radical Activity

1Bristol The reduction of nitroblue tetrazolium (NBT) by glycated proteins forms the basis of the fructosamine assay. Super oxide dismutase (SOD) inhibits this reduction and the greater inhibition that has been found in diabetics has been considered as evidence that diabetics have increased free radical activity (FRA) (Jones et al, Clin Chem 1987; 33:147–149).

1Bristol The reduction of nitroblue tetrazolium (NBT) by glycated proteins forms the basis of the fructosamine assay. Super oxide dismutase (SOD) inhibits this reduction and the greater inhibition that has been found in diabetics has been considered as evidence that diabetics have increased free radical activity (FRA) (Jones et al, Clin Chem 1987; 33:147–149).

1Bristol The reduction of nitroblue tetrazolium (NBT) by glycated proteins forms the basis of the fructosamine assay. Super oxide dismutase (SOD) inhibits this reduction and the greater inhibition that has been found in diabetics has been considered as evidence that diabetics have increased free radical activity (FRA) (Jones et al, Clin Chem 1987; 33:147–149).

1Bristol The reduction of nitroblue tetrazolium (NBT) by glycated proteins forms the basis of the fructosamine assay. Super oxide dismutase (SOD) inhibits this reduction and the greater inhibition that has been found in diabetics has been considered as evidence that diabetics have increased free radical activity (FRA) (Jones et al, Clin Chem 1987; 33:147–149).