The Editorial Office has been made aware of potential issues surrounding the scientific validity of the paper “Angiopoietin-1 gene transfer improves impaired wound healing in genetically diabetic mice without increasing VEGF expression” DOI: 10.1042/CS20070250, hence has issued an expression of concern to notify readers whilst the Editorial Office investigates. It has been noted that there appears to be similarities between some of the Western blot protein bands in Figure 2. Additionally, part of Figure 5 db+/db+ + rAVV Ang-1 panel appears similar to part of Figure 5B db+/db+ plus simvastatin panel from Bitto et al, 2008 (DOI: 10.1016/j.phrs.2008.01.005). The Editorial Office have contacted the authors, who have responded to the Journal's queries. The authors state that due to the age of the paper, the original data for Figure 2 is no longer available. As the concerns for Figure 2 and Figure 5B still stand, the Journal is issuing an expression of concern.
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August 2024
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The cover of this edition of Clinical Science is comprised of representative images for pericyte markers including CD13 (top left), PDGFRβ (top right), NG2 (bottom right) and Atp13a5 (bottom left). Immunocytochemistry results provide evidence that some cells show greater staining for α-SMA (centre) and NG2 while all cells stain positive for PDGRβ, CD13, and ATP13a5 under normal growth conditions. Read more from Edgerton-Fulton and colleagues on pp 1009 – 1022.
Expression of Concern|
August 21 2024
Expression of Concern: Angiopoietin-1 gene transfer improves impaired wound healing in genetically diabetic mice without increasing VEGF expression
Publisher: Portland Press Ltd
Online ISSN: 1470-8736
Print ISSN: 0143-5221
© 2024 The Author(s).
2024
This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY).
Clin Sci (Lond) (2024) 138 (16): 1023.
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This is an Expression of Concern to:
Angiopoietin-1 gene transfer improves impaired wound healing in genetically diabetic mice without increasing VEGF expression
Citation
Expression of Concern: Angiopoietin-1 gene transfer improves impaired wound healing in genetically diabetic mice without increasing VEGF expression. Clin Sci (Lond) 21 August 2024; 138 (16): 1023. doi: https://doi.org/10.1042/CS-2007-0250_EOC
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