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ACE2, a multifunctional protein – from cardiovascular regulation to COVID-19

Guest edited by Professor Michael Bader, Professor Anthony J. Turner and Dr Natalia Alenina.

Twenty years after its discovery, angiotensin-converting enzyme 2 (ACE2) has become one of the most studied proteins. Since ACE2 was identified as the SARS-coronavirus 2 receptor, it has held centre stage with already around 3000 peer-reviewed publications in 2020. On this occasion Clinical Science has compiled a themed collection ‘ACE2, a multifunctional protein – from cardiovascular regulation to COVID-19’ with reviews and original papers on the physiological and pathophysiological roles of the multiple known tasks of ACE2 including carboxypeptidase, amino acid transport regulator, and virus receptor functions.

Collection image featured in 10.1042/CS20200477. Modified from 10.1126/science.abb2762.

Special Collection Image
Xi Cao; Li-Ni Song; Jin-Kui Yang
Jithin Kuriakose; Augusto C. Montezano; Rhian M. Touyz
Shrinidh Joshi; Ildamaris Montes de Oca; Ahmad Maghrabi; Christine Lopez-Yang; Julio Quiroz-Olvera; Charles A. Garcia; Yagna Prasada Rao Jarajapu
Ravindra K. Sharma; Jing Li; Suraj Krishnan; Elaine M. Richards; Mohan K. Raizada; Rajesh Mohandas
Michael Bader; Anthony J. Turner; Natalia Alenina
Fiona J. Warner; Harinda Rajapaksha; Nicholas Shackel; Chandana B. Herath
Tatiane Cristine Silva de Almeida; Katharina Lanza; Roberta da Silva Filha; Leda Maria de Castro C. Campos; Esdras G. Fonseca; Mariana W. Chagas; Natalia Pessoa Rocha; Marcos Augusto de Sá; Maria Aparecida Ribeiro Vieira; Marcelo Vidigal Caliari; Lucas M. Kangussu; Anderson José Ferreira; Ana Cristina Simões e Silva
Thiago Verano-Braga; Ana Luiza Valle Martins; Daisy Motta-Santos; Maria José Campagnole-Santos; Robson Augusto Souza Santos
Koichi Yamamoto; Hikari Takeshita; Hiromi Rakugi
U. Muscha Steckelings; Colin Sumners
Fernando M. Reis; Adelina M. Reis
Lizelle Lubbe; Gyles E. Cozier; Delia Oosthuizen; K. Ravi Acharya; Edward D. Sturrock
Simone M.R. Camargo; Raphael N. Vuille-dit-Bille; Chantal F. Meier; François Verrey
Enrique Lores; Jan Wysocki; Daniel Batlle
Carlos M. Ferrario; Sarfaraz Ahmad; Leanne Groban
Qiuhong Li; Maria B. Grant; Elaine M. Richards; Mohan K. Raizada
Mazher Mohammed; Clara Berdasco; Eric Lazartigues
Nigel M. Hooper; Daniel W. Lambert; Anthony J. Turner
Paulami Chatterjee; Mahmoud Gheblawi; Kaiming Wang; Jeannie Vu; Palsa Kondaiah; Gavin Y. Oudit
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