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Medical Research Society Meeting 4 February 2002

Communication

Control of Retinal Angiogenesis by Local Gene Tranfer of a VEGF Inhibitor

James Bainbridge; Ajay Mistry; Mahesh De Alwis; Adrian Thrasher; Robin Ali

Clin Sci (Lond) (2002) 103 (s47): 1P.

View Articletitled, Control of Retinal Angiogenesis by Local Gene Tranfer of a VEGF Inhibitor

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Macrophage Release of Tumour Necrosis Factor Directs Mesangial Cell Apoptosis and is Inhibited by Uptake of Apoptotic Cells; a Negative Feedback Loop in the Inflammatory Response

J.S. Duffield; C.F. Ware; B. Ryffel; J.S. Savill

Clin Sci (Lond) (2002) 103 (s47): 1P.

View Articletitled, Macrophage Release of Tumour Necrosis Factor Directs Mesangial Cell Apoptosis and is Inhibited by Uptake of Apoptotic Cells; a Negative Feedback Loop in the Inflammatory Response

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Functional Implications of Genetic Variation in Non-Coding DNA for Disease Susceptibility and Gene Regulation

Julian Knight; Brendan Keating; Dominic Kwiatkowski

Clin Sci (Lond) (2002) 103 (s47): 1P–2P.

View Articletitled, Functional Implications of Genetic Variation in Non-Coding DNA for Disease Susceptibility and Gene Regulation

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Human CD4⁺CD25⁺ Cells: a Unique Population of Regulatory Cells

NG Wf; F Ponchel; P Duggan; G Lombardi; AD Edwards; JD Isaacs; A Godkin; RI Lechler

Clin Sci (Lond) (2002) 103 (s47): 2P.

View Articletitled, Human CD4+CD25+ Cells: a Unique Population of Regulatory Cells

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Identification and Characterisation of Derp1-Specific CD8+ T Cells in the Peripheral Blood of Atopic Individuals

S Seneviratne; L Jones; A King; A Black; S Powell; A McMichael; GS Ogg

Clin Sci (Lond) (2002) 103 (s47): 2P.

View Articletitled, Identification and Characterisation of Derp1-Specific CD8+ T Cells in the Peripheral Blood of Atopic Individuals

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α-Synuclein and the Molecular Mechanisms of Lewy Body Formation in Parkinson's Disease

AR Saha; DP Hanger; BH Anderton

Clin Sci (Lond) (2002) 103 (s47): 2P–3P.

View Articletitled, α-Synuclein and the Molecular Mechanisms of Lewy Body Formation in Parkinson's Disease

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Expression Analysis of HIV-binding Lectin, DC-SIGN

E.J. Soilleux; L.S. Morris; J. Trowsdale; B. Lee; N. Coleman

Clin Sci (Lond) (2002) 103 (s47): 3P.

View Articletitled, Expression Analysis of HIV-binding Lectin, DC-SIGN

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Cardiopulmonary Bypass (Cpb)- and Lps-Induced Pro-Inflammatory and Cytotoxic Activity in the Plasma of Patients Undergoing Coronary Bypass Surgery (Cabg).

N. Marczin; R. Bundy; G. Hoare; M. Yacoub

Clin Sci (Lond) (2002) 103 (s47): 3P.

View Articletitled, Cardiopulmonary Bypass (Cpb)- and Lps-Induced Pro-Inflammatory and Cytotoxic Activity in the Plasma of Patients Undergoing Coronary Bypass Surgery (Cabg).

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Characterisation and Functional Analysis of the Glyoxalase-1 Gene

C.P. Gale; B.I. Hudson; P.A. Cordell; P.J. Grant

Clin Sci (Lond) (2002) 103 (s47): 3P–4P.

View Articletitled, Characterisation and Functional Analysis of the Glyoxalase-1 Gene

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Mfex, An Atypical K50 Homeodomain Protein Expressed during Heart Morphogenesis

F.T. Leong; A.J. Mighell

Clin Sci (Lond) (2002) 103 (s47): 4P.

View Articletitled, Mfex, An Atypical K50 Homeodomain Protein Expressed during Heart Morphogenesis

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Alterations of Thrombogenesis, Endothelial Damage and Platelet Function following Percutaneous Peripheral Artery Angiography and Angioplasty

A J Makin; NAY Chung; MS Moss; SH Silverman; GYH Lip

Clin Sci (Lond) (2002) 103 (s47): 4P.

View Articletitled, Alterations of Thrombogenesis, Endothelial Damage and Platelet Function following Percutaneous Peripheral Artery Angiography and Angioplasty

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Alterations of Thrombogenesis, Endothelial Damage and Oxidative Stress with Reperfusion during Femoral Artery Bypass Surgery for Peripheral Vascular Disease

A J Makin; NAY Chung; SH Silverman; GYH Lip

Clin Sci (Lond) (2002) 103 (s47): 4P–5P.

View Articletitled, Alterations of Thrombogenesis, Endothelial Damage and Oxidative Stress with Reperfusion during Femoral Artery Bypass Surgery for Peripheral Vascular Disease

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Does Vascular Endothelial Growth Factor Mediate the Hypercoagulable State in Atrial Fibrillation?

Natali A.Y. Chung; Foo L. Li-Saw-Hee; Funmi Belgore; Gregory Y.H. Lip

Clin Sci (Lond) (2002) 103 (s47): 5P.

View Articletitled, Does Vascular Endothelial Growth Factor Mediate the Hypercoagulable State in Atrial Fibrillation?

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The Effect of Blood Pressure on Plasma Levels of von Willebrand factor and Soluble P-Selectin in Patients with Atrial Fibrillation

Dwayne SG Conway; Lesly A. Pearce; Bernard SP Chin; Robert G. Hart; Gregory YH Lip

Clin Sci (Lond) (2002) 103 (s47): 5P.

View Articletitled, The Effect of Blood Pressure on Plasma Levels of von Willebrand factor and Soluble P-Selectin in Patients with Atrial Fibrillation

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Clinical Risk of Stroke in Atrial Fibrillation is Unrelated to Platelet Activation

Dwayne SG Conway; Lesly A. Pearce; Bernard SP Chin; Robert G. Hart; Gregory YH Lip

Clin Sci (Lond) (2002) 103 (s47): 5P–6P.

View Articletitled, Clinical Risk of Stroke in Atrial Fibrillation is Unrelated to Platelet Activation

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Plasma Androgens and Heart Rate Variability in Men with Heart Failure

PJ Pugh; RD Jones; TH Jones; KS Channer

Clin Sci (Lond) (2002) 103 (s47): 6P.

View Articletitled, Plasma Androgens and Heart Rate Variability in Men with Heart Failure

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Oxidised Ldl Induces Increased Expression of Angiopoietin-2 in Human Endothelial Cells

Peter Henriksen; Christopher Haslett; David Webb; Jean-Michel Sallenave; Yuri Kotelevtsev

Clin Sci (Lond) (2002) 103 (s47): 6P.

View Articletitled, Oxidised Ldl Induces Increased Expression of Angiopoietin-2 in Human Endothelial Cells

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The Role of Nitric Oxide in Therapeutic and Endogenous Angiogenesis and Arteriogenesis

Timothy Ja Chico; JM Greve; H Steinmetz; N VanBruggen; S Bunting

Clin Sci (Lond) (2002) 103 (s47): 6P–7P.

View Articletitled, The Role of Nitric Oxide in Therapeutic and Endogenous Angiogenesis and Arteriogenesis

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Monocyte Adhesion Molecule Modulation by Lipid Microenvironment

J Sarma; KAA Fox; C Haslett; I Dransfield

Clin Sci (Lond) (2002) 103 (s47): 7P.

View Articletitled, Monocyte Adhesion Molecule Modulation by Lipid Microenvironment

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Plethysmography without Venous Occlusion for Forearm Blood Flow Measurement – a Comparison with Venous Occlusive Method

SS Chuah; BR Pullan; PS Lewis

Clin Sci (Lond) (2002) 103 (s47): 7P.

View Articletitled, Plethysmography without Venous Occlusion for Forearm Blood Flow Measurement – a Comparison with Venous Occlusive Method

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Upright Posture Impairs Microvascular Vasodilation in Patients with Varicose Veins – Possible Role in Ulcer Formation

JMC Yeung; M Klonizakis; JR Nash; MK Lingam; G Manning; R Donnelly

Clin Sci (Lond) (2002) 103 (s47): 7P–8P.

View Articletitled, Upright Posture Impairs Microvascular Vasodilation in Patients with Varicose Veins – Possible Role in Ulcer Formation

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Acute Systemic Inflammation Enhances Tissue Plasminogen Activator Release in Man

S Chia; K Reid; P Dawson; CA Ludlam; KAA Fox; DE Newby

Clin Sci (Lond) (2002) 103 (s47): 8P.

View Articletitled, Acute Systemic Inflammation Enhances Tissue Plasminogen Activator Release in Man

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Endothelial Dysfunction and Impaired Endogenous Fibrinolysis Do Not Contribute to Acute Stent Thrombosis or In-stent Restenosis

S Chia; EL Megson; SA Harding; CA Ludlam; KAA Fox; NA Boon; DE New

Clin Sci (Lond) (2002) 103 (s47): 8P.

View Articletitled, Endothelial Dysfunction and Impaired Endogenous Fibrinolysis Do Not Contribute to Acute Stent Thrombosis or In-stent Restenosis

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Alterations in Single-Cell Calcium Handling Could Contribute to Diastolic Dysfunction and Arrhythmogenesis in Heart Failure

F. Russell Quinn; Stuart M. Cobbe; Godfrey L. Smith

Clin Sci (Lond) (2002) 103 (s47): 8P–9P.

View Articletitled, Alterations in Single-Cell Calcium Handling Could Contribute to Diastolic Dysfunction and Arrhythmogenesis in Heart Failure

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Effects of Overexpression of Igf Binding Protein-1 on Vascular Function and Blood Pressure Homeostasis in Mice

SB Wheatcroft; IL Williams; AM Shah; PA Crossey; MT Kearney

Clin Sci (Lond) (2002) 103 (s47): 9P.

View Articletitled, Effects of Overexpression of Igf Binding Protein-1 on Vascular Function and Blood Pressure Homeostasis in Mice

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Activation of Human Protease Activated Receptor 2 Dilates Veins and Resistance Vessels In Vivo

Jonathan Robin; Patrick Vallance

Clin Sci (Lond) (2002) 103 (s47): 9P.

View Articletitled, Activation of Human Protease Activated Receptor 2 Dilates Veins and Resistance Vessels In Vivo

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Selective Inhibition of Arrhythmogenic but Not Inotropic Effects of Ca Loading in Cardiac Muscle

L. Venetucci; D.A. Eisner

Clin Sci (Lond) (2002) 103 (s47): 9P–10P.

View Articletitled, Selective Inhibition of Arrhythmogenic but Not Inotropic Effects of Ca Loading in Cardiac Muscle

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Regional Differences in Excitation-Contraction Coupling

Helen L. Wallis; Claire Sears; Simon Bryant

Clin Sci (Lond) (2002) 103 (s47): 10P.

View Articletitled, Regional Differences in Excitation-Contraction Coupling

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Relationship between Androgens and Arterial Stiffness Indices in Men and Women

F Dockery; C Rajkumar; M Donaldson; S Fernandez; CJ Bulpitt

Clin Sci (Lond) (2002) 103 (s47): 10P.

View Articletitled, Relationship between Androgens and Arterial Stiffness Indices in Men and Women

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Androgen Suppression in Men Leads to Increased Arterial Stiffness and Hyperinsulinaemia

F. Dockery; C. Rajkumar; S Agarwal; M Donaldson; CJ Bulpitt

Clin Sci (Lond) (2002) 103 (s47): 10P–11P.

View Articletitled, Androgen Suppression in Men Leads to Increased Arterial Stiffness and Hyperinsulinaemia

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Effects of Blood Pressure and Anemia on Functional Abnormalities in the Uraemic Heart Using Cardiovascular Magnetic Resonance

N Johnston; G Stewart; A Jardine; H Dargie

Clin Sci (Lond) (2002) 103 (s47): 11P.

View Articletitled, Effects of Blood Pressure and Anemia on Functional Abnormalities in the Uraemic Heart Using Cardiovascular Magnetic Resonance

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The Determinants of Coronary Atheroma in Patients with Chronic Renal Failure

N Johnston; A Jardine; H Dargie

Clin Sci (Lond) (2002) 103 (s47): 11P.

View Articletitled, The Determinants of Coronary Atheroma in Patients with Chronic Renal Failure

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Heritability of Homocysteine, Folate and B12

A. Siva; M. Ashby; S. Peachey; M. Chiano; MJ Brown

Clin Sci (Lond) (2002) 103 (s47): 11P–12P.

View Articletitled, Heritability of Homocysteine, Folate and B12

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Generation and Characterisation of a Potential Mouse Model of LQT3

C E G Head; AA Grace; W H Colledge

Clin Sci (Lond) (2002) 103 (s47): 12P.

View Articletitled, Generation and Characterisation of a Potential Mouse Model of LQT3

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Arrhythmogenic Right Ventricular Cardiomyopathy: Is there an Extended Phenotype?

M.S. Hamid; M. Norman; J.R. Gimeno; S. Firoozi; A. Quareshi; B. Sachdev; R. Thaman; P. Elliott; W.J. McKenna

Clin Sci (Lond) (2002) 103 (s47): 12P.

View Articletitled, Arrhythmogenic Right Ventricular Cardiomyopathy: Is there an Extended Phenotype?

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Relaxin, a Newly Described Cardiac Hormone, is a More Potent Vasodilator than Atrial Natriuretic Factor in Human Resistance arteries

CJ Fisher; F Johnston; C Hillier; JJ McMurray

Clin Sci (Lond) (2002) 103 (s47): 12P.

View Articletitled, Relaxin, a Newly Described Cardiac Hormone, is a More Potent Vasodilator than Atrial Natriuretic Factor in Human Resistance arteries

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Dietary Copper Supplementation Enhances Vascular Function in a C57/Bl6 Mouse

ML Tickner; DJ Lamb; SMO Hourani; GAA Ferns

Clin Sci (Lond) (2002) 103 (s47): 13P.

View Articletitled, Dietary Copper Supplementation Enhances Vascular Function in a C57/Bl6 Mouse

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First Demonstration in Humans of Systemic Neutral Endopeptidase and Endothelin Converting Enzyme Inhibition Using a New, Orally Active, Dual Metalloprotease Inhibitor, Slv 306

Alison Seed; Rhoda Kuc; Anthony Davenport; Michael Ashby; Chris Hillier; Paul Passier; Hans Essers; John McMurray

Clin Sci (Lond) (2002) 103 (s47): 13P.

View Articletitled, First Demonstration in Humans of Systemic Neutral Endopeptidase and Endothelin Converting Enzyme Inhibition Using a New, Orally Active, Dual Metalloprotease Inhibitor, Slv 306

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Interaction between Neutral Endopeptidase and Angiotensin Converting Enzyme Inhibition

Alison Seed; Chris Hillier; Colin Berry; Fiona Johnston; Amanda Brown; Mark Petrie; John JV McMurray

Clin Sci (Lond) (2002) 103 (s47): 13P.

View Articletitled, Interaction between Neutral Endopeptidase and Angiotensin Converting Enzyme Inhibition

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Evidence that a Novel Orally Active Nep/Ece Inhibitor Blocks the Vasoconstrictor Response to Big Endothelin in Human Resistance Arteries

A Seed; C Hillier; C Berry; F Johnston; M Petrie; JJV McMurray

Clin Sci (Lond) (2002) 103 (s47): 14P.

View Articletitled, Evidence that a Novel Orally Active Nep/Ece Inhibitor Blocks the Vasoconstrictor Response to Big Endothelin in Human Resistance Arteries

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Intercellular Trafficking of Vp22 Fusion Proteins to Enhance the Effects of Vascular Gene Delivery

P Sheridan; C Holt; C Newman; D Crossman

Clin Sci (Lond) (2002) 103 (s47): 14P.

View Articletitled, Intercellular Trafficking of Vp22 Fusion Proteins to Enhance the Effects of Vascular Gene Delivery

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Adenovirus-Mediated Intra-Coronary Delivery of the Gene for Transforming Growth Factor-β3 (TGF-β3) Reduces Luminal Loss and Inhibits Constrictive Remodelling after Porcine PTCA

Paul A Kingston; Clare E Appleby; Anthony M Heagerty

Clin Sci (Lond) (2002) 103 (s47): 14P.

View Articletitled, Adenovirus-Mediated Intra-Coronary Delivery of the Gene for Transforming Growth Factor-β3 (TGF-β3) Reduces Luminal Loss and Inhibits Constrictive Remodelling after Porcine PTCA

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Tissue Specific Knockout of the Mouse Endothelin B receptor

Dr Alan Bagnall; David Webb; Dr Yuri Kotelevtsev

Clin Sci (Lond) (2002) 103 (s47): 15P.

View Articletitled, Tissue Specific Knockout of the Mouse Endothelin B receptor

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Characterisation Cardiac Hypertrophy in the Inducible Hypertensive Rat

A. Ryding; G. Brooker; S. Kantachuvesiri; J. Peters; M. Denvir; J. Mullins

Clin Sci (Lond) (2002) 103 (s47): 15P.

View Articletitled, Characterisation Cardiac Hypertrophy in the Inducible Hypertensive Rat

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Metabolism of Endogenous Nos Inhibitors Lowers Blood Pressure and Regulates Nitric Oxide Synthesis following Hindlimb Ischaemia

V Achan; M Stuehlinger; S Adimoolam; P Tsao; M Kimoto; AJ Patterson; P Vallance; JP Cooke

Clin Sci (Lond) (2002) 103 (s47): 15P.

View Articletitled, Metabolism of Endogenous Nos Inhibitors Lowers Blood Pressure and Regulates Nitric Oxide Synthesis following Hindlimb Ischaemia

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Uncomplicated Acute Myocardial Infarction Results in Protracted Sympathetic Hyperactivity after Discharge from Hospital

LN Graham; PA Smith; JB Stoker; AF MacKintosh; DA Mary

Clin Sci (Lond) (2002) 103 (s47): 16P.

View Articletitled, Uncomplicated Acute Myocardial Infarction Results in Protracted Sympathetic Hyperactivity after Discharge from Hospital

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Hypertrophic Cardiomyopathy Fibrosis Imaging by MRI

J. Moon

Clin Sci (Lond) (2002) 103 (s47): 16P.

View Articletitled, Hypertrophic Cardiomyopathy Fibrosis Imaging by MRI

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Genetic Variation of the Beta-1 Adrenoceptor Affects Left Ventricular Mass

T Stanton; S Padmanabhan; A G Jardine; A Mc Connachie; M Upton; G Watt; A F Dominiczak; J M C Connell

Clin Sci (Lond) (2002) 103 (s47): 16P.

View Articletitled, Genetic Variation of the Beta-1 Adrenoceptor Affects Left Ventricular Mass

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A Cause for Central Sympathetic Hyperactivity in Hypertension

PA Smith; LN Graham; JB Stoker; AF MacKintosh; Dasg Mary

Clin Sci (Lond) (2002) 103 (s47): 17P.

View Articletitled, A Cause for Central Sympathetic Hyperactivity in Hypertension

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A Cardiac Nitric Oxide Synthase 1 Regulates Contraction and Calcium Fluxes – a Novel Mechanism Involved in the Autocrine Control of Cardiac Function

Euan Ashley; Claire Sears; Simon Bryant; Hugh Watkins; Barbara Casadci

Clin Sci (Lond) (2002) 103 (s47): 17P.

View Articletitled, A Cardiac Nitric Oxide Synthase 1 Regulates Contraction and Calcium Fluxes – a Novel Mechanism Involved in the Autocrine Control of Cardiac Function

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Using Transgenic Xenopus to Investigate the Embryonic Cardiovascular System

Ross A. Breckenridge; T. J. Mohun; Enrique Amaya

Clin Sci (Lond) (2002) 103 (s47): 17P–18P.

View Articletitled, Using Transgenic Xenopus to Investigate the Embryonic Cardiovascular System

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Diazoxide and Ischaemic Preconditioning Act Differently on the Mitochondria: Is the Mitokatp Channel a Red Herring?

KHH Lim; SA Javadov; SJ Clarke; M-S Suleiman; GD Angelini; AP Halestrap

Clin Sci (Lond) (2002) 103 (s47): 18P.

View Articletitled, Diazoxide and Ischaemic Preconditioning Act Differently on the Mitochondria: Is the Mitokatp Channel a Red Herring?

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Nitric Oxide Activity is Enhanced following Ingestion of Red Wine

RA Barnes; SL Nuttall; NJ Langford; MJ Kendall

Clin Sci (Lond) (2002) 103 (s47): 18P.

View Articletitled, Nitric Oxide Activity is Enhanced following Ingestion of Red Wine

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Elevated Circulating Interleukin-6 Levels in Acute Ischaemic Stroke Are Correlated with Ct Infarct Volume and Poor Clinical Outcome

Hedley CA Emsley; Craig J Smith

Clin Sci (Lond) (2002) 103 (s47): 18P–19P.

View Articletitled, Elevated Circulating Interleukin-6 Levels in Acute Ischaemic Stroke Are Correlated with Ct Infarct Volume and Poor Clinical Outcome

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Glucagon Stimulation in Pre-Term Infants: Markers of Insulin Resistance Predict Response

L. Jackson; A. McGeechan; A. Burchell; R. Hume

Clin Sci (Lond) (2002) 103 (s47): 19P.

View Articletitled, Glucagon Stimulation in Pre-Term Infants: Markers of Insulin Resistance Predict Response

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The Genetic Association between Leptin and Human Puberty

JA Trueman; CM Hall; RJM Ross; DA Price; L Patel; PE Clayton

Clin Sci (Lond) (2002) 103 (s47): 19P.

View Articletitled, The Genetic Association between Leptin and Human Puberty

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Lack of Ketone Body Response Associated with Hyperglycaemia following Pancreatectomy for Hyperinsulinism (Hi)

K. Hussain; P. Mainie; S. Krywawych; P. Hindmarslv; Aynsley Green

Clin Sci (Lond) (2002) 103 (s47): 19P.

View Articletitled, Lack of Ketone Body Response Associated with Hyperglycaemia following Pancreatectomy for Hyperinsulinism (Hi)

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β-Adrenoceptor- and Adenylyl Cyclase Mediated Platelet Nitric Oxide Generation Are Impaired in Type 2 Diabetes

L.R. Queen; A. Ferro

Clin Sci (Lond) (2002) 103 (s47): 20P.

View Articletitled, β-Adrenoceptor- and Adenylyl Cyclase Mediated Platelet Nitric Oxide Generation Are Impaired in Type 2 Diabetes

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Frequent Occurrence of An Intron 4 Mutation in Multiple Endocrine Neoplasia Type 1 (Men1)

J J O Turner; P D Leotlela; A A J Pannett; B Harding; R V Thakker

Clin Sci (Lond) (2002) 103 (s47): 20P.

View Articletitled, Frequent Occurrence of An Intron 4 Mutation in Multiple Endocrine Neoplasia Type 1 (Men1)

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Phenocopies in Multiple Endocrine Neoplasia Type 1 (Men1) Present Diagnostic Challenges

J J O Turner; J M Stacey; A A J Pannett; R V Thakker

Clin Sci (Lond) (2002) 103 (s47): 20P.

View Articletitled, Phenocopies in Multiple Endocrine Neoplasia Type 1 (Men1) Present Diagnostic Challenges

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The Role of Cortisol Metabolism in the Pathogenesis of Central Obesity

JW Tomlinson; B Sinha; M Hewison; PM Stewart

Clin Sci (Lond) (2002) 103 (s47): 21P.

View Articletitled, The Role of Cortisol Metabolism in the Pathogenesis of Central Obesity

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Leukocyte Actin Assembly in Response to Tyrosine Phosphorylation is Impaired in Type 2 Diabetes

A. Advani; S.M. Marshall; T.H. Thomas

Clin Sci (Lond) (2002) 103 (s47): 21P.

View Articletitled, Leukocyte Actin Assembly in Response to Tyrosine Phosphorylation is Impaired in Type 2 Diabetes

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A Digenic Basis for Severe Insulin Resistance in a Large Human Kindred

DB Savage; M Gurnell; I Barroso; M Agostini; O Rajanayagam; M Soos; G Ihrke; A Schafer; R Ross; S O'Rahilly; VKK Chatterjee

Clin Sci (Lond) (2002) 103 (s47): 21P–22P.

View Articletitled, A Digenic Basis for Severe Insulin Resistance in a Large Human Kindred

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Naturally-Occurring Mutations in Steroidogenic Factor-1 (Sf-1) Provide Insight into Dose-Dependent Regulation of Gene Transcription by Monomeric Orphan Nuclear Receptors

John C Achermann; Gokhan Ozisik; Masafumi Ito; Utku A Orun; Peter C Hindmarsh; J Larry Jameson

Clin Sci (Lond) (2002) 103 (s47): 22P.

View Articletitled, Naturally-Occurring Mutations in Steroidogenic Factor-1 (Sf-1) Provide Insight into Dose-Dependent Regulation of Gene Transcription by Monomeric Orphan Nuclear Receptors

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Cell Cycle Dysregulation in Human Pituitary Tumours

Márta Korbonits; Ashley B. Grossman

Clin Sci (Lond) (2002) 103 (s47): 22P.

View Articletitled, Cell Cycle Dysregulation in Human Pituitary Tumours

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Autocrine Activation of Glucocorticoids in Osteoblasts Increases with Age and Glucocorticoid Exposure

M.S. Cooper; M. Hewison; W.A. Bartlett; P.M. Stewart

Clin Sci (Lond) (2002) 103 (s47): 22P–23P.

View Articletitled, Autocrine Activation of Glucocorticoids in Osteoblasts Increases with Age and Glucocorticoid Exposure

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A_2B Adenosine Receptors Mediate the Adenosine-Induced Increase in Cell Growth and IL-6 Expression in Pituitary Folliculostellate Cells

D.A. Rees; M.D. Lewis; B.M. Lewis; M.F. Scanlon; J. Ham

Clin Sci (Lond) (2002) 103 (s47): 23P.

View Articletitled, A2B Adenosine Receptors Mediate the Adenosine-Induced Increase in Cell Growth and IL-6 Expression in Pituitary Folliculostellate Cells

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Diabetes in An Hiv Population: A Hidden Epidemic?

YP Samarasinghe; C Higgs; B Gazzard; MD Feher

Clin Sci (Lond) (2002) 103 (s47): 23P.

View Articletitled, Diabetes in An Hiv Population: A Hidden Epidemic?

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Reduced Adipose Tissue Sympathetic Nervous System (SNS) Activity in Human Obesity despite Increased Whole Body Norepinephrine Spillover

VJ Lawrence; JN Patel; G Eisenhofer; SW Coppack

Clin Sci (Lond) (2002) 103 (s47): 23P–24P.

View Articletitled, Reduced Adipose Tissue Sympathetic Nervous System (SNS) Activity in Human Obesity despite Increased Whole Body Norepinephrine Spillover

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Optimisation of Hydrocortisone Replacement Therapy

P.M. Mah; R.C. Jenkins; A. Rostami-Hodjegan; J. Newell-Price; A. Doane; V. Ibbotson; G. Tucker; R.J. Ross

Clin Sci (Lond) (2002) 103 (s47): 24P.

View Articletitled, Optimisation of Hydrocortisone Replacement Therapy

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Mapping of Familial Juvenile Hyperuricaemic Nephropathy on Chromosome 16P12 in Six Families

J J O Turner; J M Stacey; B Harding; M A Nesbit; P Kotanko; K Lhotta; J G Puig; R J Torres; R V Thakker

Clin Sci (Lond) (2002) 103 (s47): 24P.

View Articletitled, Mapping of Familial Juvenile Hyperuricaemic Nephropathy on Chromosome 16P12 in Six Families

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Tolerance Induction Using Nondepleting Anti-Cm, Soluble Interleukin-1 Receptor and Insulin in Nod Syngeneic Islet Grafts

M Drage; J Phillips; F Nicoletti; J Dawson; JA Bradley; A Cooke

Clin Sci (Lond) (2002) 103 (s47): 24P.

View Articletitled, Tolerance Induction Using Nondepleting Anti-Cm, Soluble Interleukin-1 Receptor and Insulin in Nod Syngeneic Islet Grafts

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Interleukin 10 Secretion Differentiates between Interstitial Dendritic Cells from Human Liver and Skin

Sarah Goddard; David Adams

Clin Sci (Lond) (2002) 103 (s47): 24P–25P.

View Articletitled, Interleukin 10 Secretion Differentiates between Interstitial Dendritic Cells from Human Liver and Skin

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The Phenotype of the Cd4⁺ T Lymphocyte Response May Influence the Severity of Liver Damage in Chronic Hepatitis C Infection

CL Brooks; EA Sanders; L Murphy; WM Rosenberg

Clin Sci (Lond) (2002) 103 (s47): 25P.

View Articletitled, The Phenotype of the Cd4+ T Lymphocyte Response May Influence the Severity of Liver Damage in Chronic Hepatitis C Infection

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Identification of Proteins with Anti-Microbial and Anti-Hiv Activity

DD Derry; RD Possee; GE Griffin; RJ Shattock

Clin Sci (Lond) (2002) 103 (s47): 25P.

View Articletitled, Identification of Proteins with Anti-Microbial and Anti-Hiv Activity

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Short Course Antiretroviral Therapy in Primary Hiv-1 Infection

M Brady; S Fidler; A Oxenius; R Phillips; J. Weber

Clin Sci (Lond) (2002) 103 (s47): 25P–26P.

View Articletitled, Short Course Antiretroviral Therapy in Primary Hiv-1 Infection

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Macrophages Condition the Milieu in Which Dcs Encounter Antigen

LM Stuart; K Hill; M Lucas; A Rees; J Savill; A Lacy Hulbert

Clin Sci (Lond) (2002) 103 (s47): 26P.

View Articletitled, Macrophages Condition the Milieu in Which Dcs Encounter Antigen

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A Novel Inducible Stroke Phenotype Created by Correction of Salt-Water Loss during Accelerated Hypertension

Tara Collidge; Surasak Kantachuvesiri; Joerg Peters; Stewart Fleming; John Savill; John Mullins

Clin Sci (Lond) (2002) 103 (s47): 26P.

View Articletitled, A Novel Inducible Stroke Phenotype Created by Correction of Salt-Water Loss during Accelerated Hypertension

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Rho family GTPases Integrate Angiogenic Signalling Pathways

John O Connolly; Alan Hall

Clin Sci (Lond) (2002) 103 (s47): 26P–27P.

View Articletitled, Rho family GTPases Integrate Angiogenic Signalling Pathways

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Rho Family Gtpases Regulate Endothelial Morphogenesis and Capillary Assembly

John O. Connolly; Nandi Simpson; Lindsay Hewlett; Alan Hall

Clin Sci (Lond) (2002) 103 (s47): 27P.

View Articletitled, Rho Family Gtpases Regulate Endothelial Morphogenesis and Capillary Assembly

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Optimisation of the Mhc Class I Peptide Cargo is Catalysed by Tapasin

Anthony P. Williams; Chen Au Peh; Anthony W. Purcell; James McCluskey; TIM Elliott

Clin Sci (Lond) (2002) 103 (s47): 27P.

View Articletitled, Optimisation of the Mhc Class I Peptide Cargo is Catalysed by Tapasin

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Caldesmon is a Novel Candidiate Gene for Diabetic Nephropathy

B.R. Conway; D.G. Fogarty; A.P. Maxwell

Clin Sci (Lond) (2002) 103 (s47): 27P–28P.

View Articletitled, Caldesmon is a Novel Candidiate Gene for Diabetic Nephropathy

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Factor H Mutations in Haemolytic Uracmic Syndrome Cluster in Scrs 18-20, a Domain Important for Host Cell Recognition

A Richards; MR Buddies; RL Donne; JA Goodship; THJ Goodship

Clin Sci (Lond) (2002) 103 (s47): 28P.

View Articletitled, Factor H Mutations in Haemolytic Uracmic Syndrome Cluster in Scrs 18-20, a Domain Important for Host Cell Recognition

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Frequency of Hereditary Systemic Amyloidosis among Patients with Apparent Primary Al Type

HJ Lachmann; DR Booth; A Bybee; PN Hawkins

Clin Sci (Lond) (2002) 103 (s47): 28P.

View Articletitled, Frequency of Hereditary Systemic Amyloidosis among Patients with Apparent Primary Al Type

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Cd8 Cytotoxic Lymphocyte Responses against Cytomegalovirus in Renal Transplant Patients and Healthy Individuals

Frank M Mattes; Ana L Vargas; Aycan F Hassan-Walker; Paul Sweny; Andrew Davenport; Rodney E Phillips; Paul D Griffiths; Vincent C Emery

Clin Sci (Lond) (2002) 103 (s47): 28P–29P.

View Articletitled, Cd8 Cytotoxic Lymphocyte Responses against Cytomegalovirus in Renal Transplant Patients and Healthy Individuals

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The Role of CD4⁺CD25⁺ Regulatory Cells in a Mouse Transplantation Tolerance Model: CTLA-4 and IL-10-Dependent Regulation of Skin Allograft Rejection

M. Karim; C.I. Kingsley; A.R. Bushell; P.J. Morris; K.J. Wood

Clin Sci (Lond) (2002) 103 (s47): 29P.

View Articletitled, The Role of CD4+CD25+ Regulatory Cells in a Mouse Transplantation Tolerance Model: CTLA-4 and IL-10-Dependent Regulation of Skin Allograft Rejection

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High frequencies of HTLV-I specific Thl type CD4+ T-cells in HAM/TSP patients

PKC Goon; GP Taylor; CRM Bangham

Clin Sci (Lond) (2002) 103 (s47): 29P.

View Articletitled, High frequencies of HTLV-I specific Thl type CD4+ T-cells in HAM/TSP patients

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Vigorous HIV-Specific CD4 T Cell Responses in IIIV-1 Infected African Children and Adults in the Absence of Antiretroviral Therapy

JK Sutton; R Chakraborty; R Kaul; T Rostron; A D'Agostino; P Kiama; J Kimani; J Bwayo; SL Rowland-Jones

Clin Sci (Lond) (2002) 103 (s47): 29P–30P.

View Articletitled, Vigorous HIV-Specific CD4 T Cell Responses in IIIV-1 Infected African Children and Adults in the Absence of Antiretroviral Therapy

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Cd8+ T Cell Evasion by K3 during Gamma-Herpesvirus Latency Establishment

J. S. May; X. G. Smith; H. Adler; U. Koszinowski; S. Efstathiou; P.G. Stevenson

Clin Sci (Lond) (2002) 103 (s47): 30P.

View Articletitled, Cd8+ T Cell Evasion by K3 during Gamma-Herpesvirus Latency Establishment

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Isolation and Characterisation of a Candidate Erythropoietin Responsive Gene, ERIC-1

R.N. Mullan; T.RJ. Lappin; A.P. Maxwell

Clin Sci (Lond) (2002) 103 (s47): 30P.

View Articletitled, Isolation and Characterisation of a Candidate Erythropoietin Responsive Gene, ERIC-1

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Cells of Dendritic Cell Type within the Inflamed Joints of Children with Arthritis Which Express High Levels of Receptor Activator of Nfkb (Rank) Are Also Positive for the Novel Dendritic Cell Marker, Dc-SIGN

Dr Lucy Wedderburn; Ms Hemlata Varsani; Ms Alka Patel; Professor P Woo

Clin Sci (Lond) (2002) 103 (s47): 30P–31P.

View Articletitled, Cells of Dendritic Cell Type within the Inflamed Joints of Children with Arthritis Which Express High Levels of Receptor Activator of Nfkb (Rank) Are Also Positive for the Novel Dendritic Cell Marker, Dc-SIGN

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Increases in Urinary Nitrate Excretion at Porcine Vascular Surgery Are Delayed by Methylprednisolone

RC Baker; MA Armstrong; FC Campbell; SJ Allen; A. Lewis; D'Sa AAB Barros; WT McBride

Clin Sci (Lond) (2002) 103 (s47): 31P.

View Articletitled, Increases in Urinary Nitrate Excretion at Porcine Vascular Surgery Are Delayed by Methylprednisolone

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Manipulating a Pro-Inflammatory T Cell Epitope from a Synovial Autoantigen

F Hall; K Visconti; S Parry; E Bos; H McConnell; E Mellins; G Sønderstrup

Clin Sci (Lond) (2002) 103 (s47): 31P.

View Articletitled, Manipulating a Pro-Inflammatory T Cell Epitope from a Synovial Autoantigen

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The Reconstitution of Cmv-Specific Ctl Clones and the Generation of de-novo Ctl Clones, in Recipients Following Allogeneic Haematopoietic Stem Cell Transplantation

MK Gandhi; MR Wills; AJ Carmichael; RE Marcus; JGP Sissons

Clin Sci (Lond) (2002) 103 (s47): 31P.

View Articletitled, The Reconstitution of Cmv-Specific Ctl Clones and the Generation of de-novo Ctl Clones, in Recipients Following Allogeneic Haematopoietic Stem Cell Transplantation

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Nephrotoxic Nephritis in FcRγ Chain and Fcγ receptor III Deficent Mice

R.M. Tarzi; K.A. Davies; M. Botto; M.J. Walport; H.T. Cook

Clin Sci (Lond) (2002) 103 (s47): 32P.

View Articletitled, Nephrotoxic Nephritis in FcRγ Chain and Fcγ receptor III Deficent Mice

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Evidence of Self-Hla Restriction in CD4+CD25+ Regulatory Cells

David S. Game; Robert I. Lechler

Clin Sci (Lond) (2002) 103 (s47): 32P.

View Articletitled, Evidence of Self-Hla Restriction in CD4+CD25+ Regulatory Cells

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The Role of Regulatory T Cells in Rheumatoid Arthritis

CA Lawson; F Ponchel; AW Boylston; P Emery; JD Isaacs

Clin Sci (Lond) (2002) 103 (s47): 32P.

View Articletitled, The Role of Regulatory T Cells in Rheumatoid Arthritis

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Linkage Disequilibrium at the Fc Gamma Receptor (Fcγr) Locus and Association of An Fcγr Haplotype with Rheumatoid Arthritis (RA)

AW Morgan; B Griffiths; AF Markham; P Emery; JD Isaacs

Clin Sci (Lond) (2002) 103 (s47): 33P.

View Articletitled, Linkage Disequilibrium at the Fc Gamma Receptor (Fcγr) Locus and Association of An Fcγr Haplotype with Rheumatoid Arthritis (RA)

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Isolation of Novel Candidate Auto Antigens in Rheumatoid Arthritis

D Mewar; A G Wilson; P F Watson

Clin Sci (Lond) (2002) 103 (s47): 33P.

View Articletitled, Isolation of Novel Candidate Auto Antigens in Rheumatoid Arthritis

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Highly Selected Autologous Stem Cell Transplantation in Severe Rheumatoid Arthritis with Studies of Peripheral Blood Lymphocyte (Pbl) Reconstitution, Synovial Response and Thymic Function

Sarah Bingham; Fredrique Ponchel; Douglas Veale; Richard Reece; Ursula Fearon; John Isaacs; Dennis McGonagle; John Snowden; Gareth Morgan; Paul Emery

Clin Sci (Lond) (2002) 103 (s47): 33P.

View Articletitled, Highly Selected Autologous Stem Cell Transplantation in Severe Rheumatoid Arthritis with Studies of Peripheral Blood Lymphocyte (Pbl) Reconstitution, Synovial Response and Thymic Function

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Reactive Nitrogen Species in Rheumatoid and Normal Synovium

R. Klocke; PI Mapp; JK Chana; DA Walsh; PA Gallagher; CR Stevens; DR Blake

Clin Sci (Lond) (2002) 103 (s47): 34P.

View Articletitled, Reactive Nitrogen Species in Rheumatoid and Normal Synovium

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Magnetic Resonance Imaging Advances Our Understanding of Disease Pathogenesis in Spondyloarthropathy

Helena Marzo-Ortega; Dennis Mc Gonagle; Philip O'Connor; Paul Emery

Clin Sci (Lond) (2002) 103 (s47): 34P.

View Articletitled, Magnetic Resonance Imaging Advances Our Understanding of Disease Pathogenesis in Spondyloarthropathy

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Magnetic Resonance Imaging as a Predictor of Neuropathic Joint Disease in Diabetes Mellitus

Adam Greenstein; Helena Marzo-Ortega; Philip O'Connor; Paul Emery; Dennis McGonagle

Clin Sci (Lond) (2002) 103 (s47): 34P.

View Articletitled, Magnetic Resonance Imaging as a Predictor of Neuropathic Joint Disease in Diabetes Mellitus

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The Use of Mri in Elucidating the Pathogenesis of Rheumatoid Arthritis (Ra) and Its Use in Understanding Response to Therapy

MA Quinn; PG Conaghan; P O'Connor; Z Karim; BJ Wakefield; P Emery

Clin Sci (Lond) (2002) 103 (s47): 35P.

View Articletitled, The Use of Mri in Elucidating the Pathogenesis of Rheumatoid Arthritis (Ra) and Its Use in Understanding Response to Therapy

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Ultrasound: A New Advance in the Diagnosis and Management of Musculoskeletal Disorders

R. Wakefield

Clin Sci (Lond) (2002) 103 (s47): 35P.

View Articletitled, Ultrasound: A New Advance in the Diagnosis and Management of Musculoskeletal Disorders

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Ultrasonography Detects Synovitis in Patients with Rheumatoid Arthritis despite ACR Remission

Andrew K. Brown; Mark A. Quinn; Zunaid Karim; Richard J. Wakefield; Philip G. Conaghan; Philip J. O'Connor; Paul Emery

Clin Sci (Lond) (2002) 103 (s47): 35P–36P.

View Articletitled, Ultrasonography Detects Synovitis in Patients with Rheumatoid Arthritis despite ACR Remission

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Genetic Analysis of the Pentraxin Genes in Sle

AI Russell; MJ Walport; TJ Vyse

Clin Sci (Lond) (2002) 103 (s47): 36P.

View Articletitled, Genetic Analysis of the Pentraxin Genes in Sle

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Basic FGF Mediates the Immediate Response of Cartilage to Injury

Tonia Vincent; Monika Hermansson; Mark Bolton; Robin Wait; Jerry Saklatvala

Clin Sci (Lond) (2002) 103 (s47): 36P.

View Articletitled, Basic FGF Mediates the Immediate Response of Cartilage to Injury

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Tenosynovial Destruction of Tendons in Rheumatoid Arthritis

Abhilash Jain; Fionula Brennan; Jagdeep Nanchahal

Clin Sci (Lond) (2002) 103 (s47): 36P–37P.

View Articletitled, Tenosynovial Destruction of Tendons in Rheumatoid Arthritis

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Pathways of the Systemic Dissemination of the Enteric Pathogen Yersinia Pseudotuberculosis

P.D. Barnes; R.R. Isberg

Clin Sci (Lond) (2002) 103 (s47): 37P.

View Articletitled, Pathways of the Systemic Dissemination of the Enteric Pathogen Yersinia Pseudotuberculosis

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Hepatic Differentiation of Murine Embryonic Stem Cells

Elizabeth A. Jones; David Tosh; David I. Wilson; Susan Lindsay; Lesley M. Forrester

Clin Sci (Lond) (2002) 103 (s47): 37P.

View Articletitled, Hepatic Differentiation of Murine Embryonic Stem Cells

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Anticipation Plays a Major Role in the Brain Processing of Human Visceral Pain

Q Aziz; LJ Gregory; L. Yagucz; SJ Coen; E. Amaro; S. Smale; AH Hobson; Williams Scr; DG Thompson

Clin Sci (Lond) (2002) 103 (s47): 37P.

View Articletitled, Anticipation Plays a Major Role in the Brain Processing of Human Visceral Pain

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The Adverse Effects of REG Gene Expression on Survival in Colorectal Cancer Are Independent of EXTL3 Expression

I.A. Hunter

Clin Sci (Lond) (2002) 103 (s47): 38P.

View Articletitled, The Adverse Effects of REG Gene Expression on Survival in Colorectal Cancer Are Independent of EXTL3 Expression

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In vitro Models of Cox-2-Positive Macrophage-Epithelial Cell Interactions during Intestinal Tumorigenesis

CW Stanley Ko; Mark A Hull

Clin Sci (Lond) (2002) 103 (s47): 38P.

View Articletitled, In vitro Models of Cox-2-Positive Macrophage-Epithelial Cell Interactions during Intestinal Tumorigenesis

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Role for Cytokines in the Aetiopathogenesis of the Premalignant Condition Barrett's Oesophagus

RC Fitzgerald; BA Onwuegbusi

Clin Sci (Lond) (2002) 103 (s47): 38P.

View Articletitled, Role for Cytokines in the Aetiopathogenesis of the Premalignant Condition Barrett's Oesophagus

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Is There a Role for Mmp19 in Gut Inflammation?

Jennings Jsr; P. Komolmit; PJ Hamlin; N. Scott; AF Markham; PA Robinson; PD Howdle

Clin Sci (Lond) (2002) 103 (s47): 39P.

View Articletitled, Is There a Role for Mmp19 in Gut Inflammation?

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Clinical Significance and Characterisation of a Human Colonic Apical Potassium (K⁺) Channel

T. Mathialahan

Clin Sci (Lond) (2002) 103 (s47): 39P.

View Articletitled, Clinical Significance and Characterisation of a Human Colonic Apical Potassium (K+) Channel

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The Novel Chemokine Sexckine and its Receptor Bonzo are Important in T Cell Positioning within the Liver

M. Heydtmann; P. Lalor; SG Hübscher; M. Briskin; DH Adams

Clin Sci (Lond) (2002) 103 (s47): 39P–40P.

View Articletitled, The Novel Chemokine Sexckine and its Receptor Bonzo are Important in T Cell Positioning within the Liver

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Inhibition of Apoptosis of Activated Hepatic Stellate Cells by Timp-1 is Mediated via Effects on Mmp Inhibition: Implications for Reversibility of Liver Fibrosis

F. Murphy; R. Issa; X. Zhou; H. Hussain; S. Ratnarajah; P. Soloway; H. Nagase; Arthur Mjp; RC Benyon; JP Iredale

Clin Sci (Lond) (2002) 103 (s47): 40P.

View Articletitled, Inhibition of Apoptosis of Activated Hepatic Stellate Cells by Timp-1 is Mediated via Effects on Mmp Inhibition: Implications for Reversibility of Liver Fibrosis

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Assessment of Patient Satisfaction: An Important Outcome in Upper Gastrointestinal Tract Cancer

JM Blazeby; J Nicklin; V Kavadas; CP Barham; D Alderson

Clin Sci (Lond) (2002) 103 (s47): 40P.

View Articletitled, Assessment of Patient Satisfaction: An Important Outcome in Upper Gastrointestinal Tract Cancer

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The Role of Transforming Growth Factor-β in the Regulation of Matrix Metalloproteinases and Tissue Inhibitors of Metalloproteinases by Pancreatic Stellate Cells: Implications for Chronic Pancreatitis

FW Shek; Walker Fmj; Pender Slf; V. Chance; EJ Williams; CD Johnson; RC Benyon; JP Iredale; DR Fine

Clin Sci (Lond) (2002) 103 (s47): 40P–41P.

View Articletitled, The Role of Transforming Growth Factor-β in the Regulation of Matrix Metalloproteinases and Tissue Inhibitors of Metalloproteinases by Pancreatic Stellate Cells: Implications for Chronic Pancreatitis

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Factor V Leiden Polymorphism and the Rate of Fibrosis Development in Chronic Hepatitis C Virus Infection

Mark Wright; Robert Goldin; Simon Hellier; Adrian Hill; RAY Apple; Suzanne Cheung; Howard Thomas; Mark Thursz

Clin Sci (Lond) (2002) 103 (s47): 41P.

View Articletitled, Factor V Leiden Polymorphism and the Rate of Fibrosis Development in Chronic Hepatitis C Virus Infection

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Regulation of P-Cadherin Expression in the Colon

Robert Hardy; Dion Morton; Janusz Jankowski

Clin Sci (Lond) (2002) 103 (s47): 41P.

View Articletitled, Regulation of P-Cadherin Expression in the Colon

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Faecal Calprotectin: A Link between Lifestyle and Colonic Neoplasia Risk

A. Poullis; R. Foster; A. Shetty; MK Fagerhol; TC Northfield; MA Mendall

Clin Sci (Lond) (2002) 103 (s47): 41P–42P.

View Articletitled, Faecal Calprotectin: A Link between Lifestyle and Colonic Neoplasia Risk

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An N-Terminally Truncated Cytoplasmic Form of Oxygen-Regulated Protein 150 (orp150), the Major Intracellular Ligand for the Anti-Proliferative Mushroom Lectin, is Essential for Nuclear Localisation Sequence (Nls)-Dependent Nuclear Protein Import in Human Intestinal Cancer Cells

LG Yu; JM Rhodes

Clin Sci (Lond) (2002) 103 (s47): 42P.

View Articletitled, An N-Terminally Truncated Cytoplasmic Form of Oxygen-Regulated Protein 150 (orp150), the Major Intracellular Ligand for the Anti-Proliferative Mushroom Lectin, is Essential for Nuclear Localisation Sequence (Nls)-Dependent Nuclear Protein Import in Human Intestinal Cancer Cells

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Altered Colonic Glycoprotein Expression in Unaffected Monozygotic Twins of Inflammatory Bowel Disease Patients

K Bodger; AR Dodson; C Tysk; F Campbell; E Lindberg; G Järnerot; JM Rhodes

Clin Sci (Lond) (2002) 103 (s47): 42P.

View Articletitled, Altered Colonic Glycoprotein Expression in Unaffected Monozygotic Twins of Inflammatory Bowel Disease Patients

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Stress Protein Expression in Human Hepatocyte Cell Lines Cultured as in Three-Dimensional (3-D) Spheroids in Alginate

S Choudhury; C Selden; M Hubank; HJF Hodgson

Clin Sci (Lond) (2002) 103 (s47): 42P–43P.

View Articletitled, Stress Protein Expression in Human Hepatocyte Cell Lines Cultured as in Three-Dimensional (3-D) Spheroids in Alginate

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Progastrin Stimulates Murine Colonic Epithelial Mitosis after Dna Damage

D.M. Pritchard; P.D. Ottewell; A.J.M. Watson; T.C. Wang; G.J. Dockray

Clin Sci (Lond) (2002) 103 (s47): 43P.

View Articletitled, Progastrin Stimulates Murine Colonic Epithelial Mitosis after Dna Damage

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Molecular Genetic Analysis of an Inherited Disorder of Pain Sensation - Familial Rectal Pain

CR Fertleman; K Parker; M Rees; RM Gardiner

Clin Sci (Lond) (2002) 103 (s47): 43P.

View Articletitled, Molecular Genetic Analysis of an Inherited Disorder of Pain Sensation - Familial Rectal Pain

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Molecular Mechanisms in Oesophageal Atresia

AS Ioannides; D. Henderson; L. Spitz; AJ Copp

Clin Sci (Lond) (2002) 103 (s47): 43P–44P.

View Articletitled, Molecular Mechanisms in Oesophageal Atresia

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Jagged and Notch Expression in Developing Human Biliary Epithelium and Reactivation in Disease on Abnormal Ductular Proliferative Cells

DM Flynn; AJ Strain; S Nijaar; MA Kilby; DA Kelly; HA Crosby

Clin Sci (Lond) (2002) 103 (s47): 44P.

View Articletitled, Jagged and Notch Expression in Developing Human Biliary Epithelium and Reactivation in Disease on Abnormal Ductular Proliferative Cells

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Hes6 Regulates Myogenic Differentiation

J Cossins; AE Vernon; Y Zhang; A Philpott; PH Jones

Clin Sci (Lond) (2002) 103 (s47): 44P.

View Articletitled, Hes6 Regulates Myogenic Differentiation

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Nnos in Developing Rat Spinal Nociceptive Responses

C.E. Urch; A. H. Dickenson

Clin Sci (Lond) (2002) 103 (s47): 44P–45P.

View Articletitled, Nnos in Developing Rat Spinal Nociceptive Responses

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Adeno-Associated Virus (Aav) as a Vector for Delivery of Chemoprotection Genes

David A Hobin; John R Arrand; Leslie J Fairbairn; Osborn B Eden

Clin Sci (Lond) (2002) 103 (s47): 45P.

View Articletitled, Adeno-Associated Virus (Aav) as a Vector for Delivery of Chemoprotection Genes

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The Ewings Sarcoma Ews/Fli-1 Protein Up-Regulates the Stromelysin and Parp Promoters in NIH-3T3 Cells

BTS Ubhi; DR Rainey; AR Craig; DM Meredith

Clin Sci (Lond) (2002) 103 (s47): 45P.

View Articletitled, The Ewings Sarcoma Ews/Fli-1 Protein Up-Regulates the Stromelysin and Parp Promoters in NIH-3T3 Cells

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The Role of Fanconi Anaemia FANCC and FANCG Genetic Variants for Susceptibility to Sporadic Childhood Myeloid Leukaemia

S Meyer; L Barber; GM Taylor; OB Eden

Clin Sci (Lond) (2002) 103 (s47): 45P–46P.

View Articletitled, The Role of Fanconi Anaemia FANCC and FANCG Genetic Variants for Susceptibility to Sporadic Childhood Myeloid Leukaemia

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Translating Lessons from Embryonic Growth Control into Cancer Therapy

A. B. Hassan

Clin Sci (Lond) (2002) 103 (s47): 46P.

View Articletitled, Translating Lessons from Embryonic Growth Control into Cancer Therapy

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Clinical Implementation of Intensity-Modulated Radiotherapy (IMRT) in the Management of Pelvic Malignancies

John Staffurth

Clin Sci (Lond) (2002) 103 (s47): 46P.

View Articletitled, Clinical Implementation of Intensity-Modulated Radiotherapy (IMRT) in the Management of Pelvic Malignancies

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Advancing the Molecular Pharmacology of Curcumin to Patients

RA Sharma; A Shafayat; SM Plummer; WP Steward; AJ Gescher

Clin Sci (Lond) (2002) 103 (s47): 46P–47P.

View Articletitled, Advancing the Molecular Pharmacology of Curcumin to Patients

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Preclinical Development of a DNA Vaccine for Colorectal Cancer

Andrew Conn; IAN Spendlove; Lindy Durrant; James Carmichael

Clin Sci (Lond) (2002) 103 (s47): 47P.

View Articletitled, Preclinical Development of a DNA Vaccine for Colorectal Cancer

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Gene Expression Profiles in Normal Pancreas and Pancreatic Adenocarcinoma

T. Crnogorac-Jurcevic; NR Lemoine

Clin Sci (Lond) (2002) 103 (s47): 47P.

View Articletitled, Gene Expression Profiles in Normal Pancreas and Pancreatic Adenocarcinoma

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Antisense Bcl-xl Knockout Switches the Response of Colon Cancer Cells to Topoisomerase I Inhibition from Senescence to Apoptosis

R.L. Hayward; J.S. MacPherson; J. Cummings; J.F. Smyth; D.I. Jodrell

Clin Sci (Lond) (2002) 103 (s47): 47P–48P.

View Articletitled, Antisense Bcl-xl Knockout Switches the Response of Colon Cancer Cells to Topoisomerase I Inhibition from Senescence to Apoptosis

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A Novel Approach to Assessing Response to Cancer Therapies Using Hybrid FDG PET

R. Francis; A. Green; S. Baig; V. Knell; RHJ Begent

Clin Sci (Lond) (2002) 103 (s47): 48P.

View Articletitled, A Novel Approach to Assessing Response to Cancer Therapies Using Hybrid FDG PET

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Genetic and Epigenetic Changes in Plasma Dna of Lung Cancer Patients

S Khan; J Coulson; P J Woll

Clin Sci (Lond) (2002) 103 (s47): 48P.

View Articletitled, Genetic and Epigenetic Changes in Plasma Dna of Lung Cancer Patients

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Computer-Administered Individual Quality of LD7E Assessments in Oncology Practice

G. Velikova; J. Brown; A. Smith; D. Stark; T. Perren; P. Wright; Peter Selby

Clin Sci (Lond) (2002) 103 (s47): 48P–49P.

View Articletitled, Computer-Administered Individual Quality of LD7E Assessments in Oncology Practice

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Candidate Genes for the 11Q Abnormality in Chronic Lymphocytic Leukaemia (CLL)

RL Auer; F Bertoni; S McElwaine; J Groet; C Jones; CD Fegan; FE Cotter

Clin Sci (Lond) (2002) 103 (s47): 49P.

View Articletitled, Candidate Genes for the 11Q Abnormality in Chronic Lymphocytic Leukaemia (CLL)

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Telomere Shortening at Diagnosis Correlates with Prognostic Score and Predicts Early Disease Progression in CML

M.W. Drummond; M. Alcorn; F. Reid; J.D.M. Campbell; Brümmendorf Holyoake; T.L. Holyoake

Clin Sci (Lond) (2002) 103 (s47): 49P.

View Articletitled, Telomere Shortening at Diagnosis Correlates with Prognostic Score and Predicts Early Disease Progression in CML

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BCL10 and Chromosome 1p in Malignant Lymphoma-an Evaluation with Fluorescent In-Situ Hybridisation

R. Achuthan; SM Bell; IM Carr; JP Leek; P. Roberts; K. Horgan; AF Markham; KA MacLennan

Clin Sci (Lond) (2002) 103 (s47): 49P–50P.

View Articletitled, BCL10 and Chromosome 1p in Malignant Lymphoma-an Evaluation with Fluorescent In-Situ Hybridisation

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Promoter Region Polymorphism in the TNF Gene and Risk of Osteolysis after Total Hip Arthroplasty

JM Wilkinson; AG Wilson; I Stockley; DA MacDonald; IR Scott; AJ Hamer; GW Duff; R Eastell

Clin Sci (Lond) (2002) 103 (s47): 50P.

View Articletitled, Promoter Region Polymorphism in the TNF Gene and Risk of Osteolysis after Total Hip Arthroplasty

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Molecular Regulation of IL-10 in Human Malaria

JN Wilson; S Usen; M Jallow; D Burgner; M Pinder; J Hull; D Kwiatkowski

Clin Sci (Lond) (2002) 103 (s47): 50P.

View Articletitled, Molecular Regulation of IL-10 in Human Malaria

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TaqI Polymorphism in the 3′ Flanking Region of the Alpha-1 Antitrypsin Gene in Children with Meningococcal Septicaemia

D Hodge; A Finn; PC Holland; D Jary; D Bonthron

Clin Sci (Lond) (2002) 103 (s47): 50P.

View Articletitled, TaqI Polymorphism in the 3′ Flanking Region of the Alpha-1 Antitrypsin Gene in Children with Meningococcal Septicaemia

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Alpers Syndrome with Mitochondrial Dna Depletion

S. Rahman; Taanman J-W; BN Harding; Morris Aam

Clin Sci (Lond) (2002) 103 (s47): 51P.

View Articletitled, Alpers Syndrome with Mitochondrial Dna Depletion

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Replication and Transcription in Fibroblasts from Patients with Emery-Dreifuss Muscular Dystrophy and Familial Partial Lipodystrophy

R.J. Piercy; A. Pombo; S.C. Brown; F. Muntoni

Clin Sci (Lond) (2002) 103 (s47): 51P.

View Articletitled, Replication and Transcription in Fibroblasts from Patients with Emery-Dreifuss Muscular Dystrophy and Familial Partial Lipodystrophy

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Analysis of a Large Kindred with Benign Familial Infantile Convulsions Confirms the Existence of a Locus on Chromosome 19q and Extends the Phenotype

Shane McKee; Anne Hughes

Clin Sci (Lond) (2002) 103 (s47): 51P.

View Articletitled, Analysis of a Large Kindred with Benign Familial Infantile Convulsions Confirms the Existence of a Locus on Chromosome 19q and Extends the Phenotype

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Effect of Cftr and Nitric Oxide on Pseudomonas Aeruginosa Pathogenesis in Human Respiratory Epithelial Cells

K.E.A. Darling; T.J. Evans

Clin Sci (Lond) (2002) 103 (s47): 52P.

View Articletitled, Effect of Cftr and Nitric Oxide on Pseudomonas Aeruginosa Pathogenesis in Human Respiratory Epithelial Cells

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Phosphodiesterase 4 Isoform Expression and Function in a Model of Macrophage Differentiation

M.C. Shepherd; G. Baillie; N.C. Thomson; M.D. Houslay

Clin Sci (Lond) (2002) 103 (s47): 52P.

View Articletitled, Phosphodiesterase 4 Isoform Expression and Function in a Model of Macrophage Differentiation

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A Genome Wide Scan Reveals a Locus for Primary Ciliary Dyskinesia (Pcd) in the Druze Population

R. Chodhari; H.M. Mitchison; R.M. Gardiner; E.M.K. Chung

Clin Sci (Lond) (2002) 103 (s47): 52P.

View Articletitled, A Genome Wide Scan Reveals a Locus for Primary Ciliary Dyskinesia (Pcd) in the Druze Population

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Determinants of Bone Health in Children and Young Adults with Cystic Fibrosis

YY Chan; CJ Taylor; N Beckles Willson; AS Rigby; NJ Bishop

Clin Sci (Lond) (2002) 103 (s47): 53P.

View Articletitled, Determinants of Bone Health in Children and Young Adults with Cystic Fibrosis

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Impact of Congenital Diaphragmatic Hernia on Lung Development: Parenchymal and Vascular Changes in an Ovine Model

SM Nelson; CA Hajivassiliou; AD Cameron; G Haddock; P Dunkley; A Cuschieri; L Robertson; RE Olver; R Hume

Clin Sci (Lond) (2002) 103 (s47): 53P.

View Articletitled, Impact of Congenital Diaphragmatic Hernia on Lung Development: Parenchymal and Vascular Changes in an Ovine Model

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Can Beta Tubulin Mutations Detected in Serum DNA Predict for Docetaxel Resistance in Advanced Non-Small Cell Lung Cancer

R Booton; D Campbell; J Anderson; T Ward; A McGowan; N Thatcher

Clin Sci (Lond) (2002) 103 (s47): 53P.

View Articletitled, Can Beta Tubulin Mutations Detected in Serum DNA Predict for Docetaxel Resistance in Advanced Non-Small Cell Lung Cancer

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ATP-Mediated Killing of Intracellular Mycobacteria by Macrophages is a P2X₇-Dependent Process Inducing Bacterial Death by Phagosome-Lysosome Fusion

Ian P. Fairbairn; Carmel B. Stober; Dinakantha S. Kumararatne; David A Lammas

Clin Sci (Lond) (2002) 103 (s47): 54P.

View Articletitled, ATP-Mediated Killing of Intracellular Mycobacteria by Macrophages is a P2X7-Dependent Process Inducing Bacterial Death by Phagosome-Lysosome Fusion

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CD98 and Galectin-3 Expression in Lung Cancer

RC Buttery; H Monaghan; DM Salter; C Haslett; T Sethi

Clin Sci (Lond) (2002) 103 (s47): 54P.

View Articletitled, CD98 and Galectin-3 Expression in Lung Cancer

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Identification and Characterisation of 3 Novel Bid Isoforms

Stephen A. Renshaw; Colin D. Bingle; Moira K.B. Whyte

Clin Sci (Lond) (2002) 103 (s47): 54P.

View Articletitled, Identification and Characterisation of 3 Novel Bid Isoforms

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Transcriptional Regulation of Phosphodiesterase 4D Splice Variant 5 (PDE4D5) in Human Airway Smooth Muscle

IR Le Jeune; SJ Hill; IP Hall

Clin Sci (Lond) (2002) 103 (s47): 55P.

View Articletitled, Transcriptional Regulation of Phosphodiesterase 4D Splice Variant 5 (PDE4D5) in Human Airway Smooth Muscle

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The Role of TLRs in Leukocyte Function

IAN Sabroe; Elizabeth C Jones; Lynne R Usher; Sudheer Alapati; Lisa C Parker; Moira KB Whyte; Steven K Dower

Clin Sci (Lond) (2002) 103 (s47): 55P.

View Articletitled, The Role of TLRs in Leukocyte Function

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A Hydrophobic Cavity in α₁-Antitrypsin Is a Target for Rational Drug Design to Prevent Polymerisation and Disease

Helen Parfrey; Ravi Mahadeva; Aiwu Zhou; Timothy R Dafforn; David A Lomas

Clin Sci (Lond) (2002) 103 (s47): 55P.

View Articletitled, A Hydrophobic Cavity in α1-Antitrypsin Is a Target for Rational Drug Design to Prevent Polymerisation and Disease

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The Selective Chemotactic Effect of α₁-Antitrypsin Polymers for Human Peripheral Blood Neutrophils

JS Parmar; D Bilton; ER Chilvers; DA Lomas

Clin Sci (Lond) (2002) 103 (s47): 56P.

View Articletitled, The Selective Chemotactic Effect of α1-Antitrypsin Polymers for Human Peripheral Blood Neutrophils

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Siblings of Patients with Severe Chronic Obstructive Pulmonary Disease Have a Significant Risk of Airflow Obstruction

Bipen D Patel; Sean C McCloskey; Susan J Hinchcliffe; Elaine D Reid; Nicholas J Wareham; David A Lomas

Clin Sci (Lond) (2002) 103 (s47): 56P.

View Articletitled, Siblings of Patients with Severe Chronic Obstructive Pulmonary Disease Have a Significant Risk of Airflow Obstruction

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The Effect of Respirable Particles on IL-8 Release from Airway Epithelial Cells

S Parnia; K Berubé; SM Puddicombe; A Richter; M Thornber; ST Holgate; AJ Frew; DE Davies

Clin Sci (Lond) (2002) 103 (s47): 56P.

View Articletitled, The Effect of Respirable Particles on IL-8 Release from Airway Epithelial Cells

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Neutrophil Elastase Participates in TGF-β Activation in Bleomycin-Induced Pulmonary Fibrosis

F Chua; SE Dunsmore; AW Segal; J Roes; GJ Laurent

Clin Sci (Lond) (2002) 103 (s47): 57P.

View Articletitled, Neutrophil Elastase Participates in TGF-β Activation in Bleomycin-Induced Pulmonary Fibrosis

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A Transpulmonary Gradient of Isoprostane 8-ISO PGF_2α Is Present in Patients with Ards

Julius H Cranshaw; Jane A Mitchell; Timothy W Evans

Clin Sci (Lond) (2002) 103 (s47): 57P.

View Articletitled, A Transpulmonary Gradient of Isoprostane 8-ISO PGF2α Is Present in Patients with Ards

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Cell Lineage-Specific Surface Molecular Alterations Associated with Neutrophil Apoptosis That Potentiate Phagocyte Recognition

Simon P. Hart; Caroline Jackson; L. Maximillian Kremmel; Hubertus Jersmann; James A. Ross; IAN Dransfield

Clin Sci (Lond) (2002) 103 (s47): 57P.

View Articletitled, Cell Lineage-Specific Surface Molecular Alterations Associated with Neutrophil Apoptosis That Potentiate Phagocyte Recognition

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Variation in Gene Polymorphisms between London and San Francisco Clinical Isolates of Mycobacterium Tuberculosis.

HO Tbl; BD Robertson; JT Rhee; PM Small; RJ Shaw; DB Young

Clin Sci (Lond) (2002) 103 (s47): 58P.

View Articletitled, Variation in Gene Polymorphisms between London and San Francisco Clinical Isolates of Mycobacterium Tuberculosis.

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Retinoic Acid induces Alveolar Regeneration in the Adult Mouse Lung

M. Hind; M. Maden

Clin Sci (Lond) (2002) 103 (s47): 58P.

View Articletitled, Retinoic Acid induces Alveolar Regeneration in the Adult Mouse Lung

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Th-2 Cytokines Regulate Transforming Growth Factor Alpha (TGFα) and Endothelin (ET-1) Production by Asthmatic Bronchial Epithelial Cells

M.D. Thornber; S.M. Puddicombe; D.E. Davies; S.T. Holgate

Clin Sci (Lond) (2002) 103 (s47): 58P.

View Articletitled, Th-2 Cytokines Regulate Transforming Growth Factor Alpha (TGFα) and Endothelin (ET-1) Production by Asthmatic Bronchial Epithelial Cells

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Inflammatory Cell Populations in Peripheral Blood and Airways following Lps Inhalation in Healthy Volunteers

MI Allenby; MW Lethbridge; RI Ketchell; A Sousa; FE Woisin; MW Jensen; DM Kemeny; BJ O' Connor

Clin Sci (Lond) (2002) 103 (s47): 59P.

View Articletitled, Inflammatory Cell Populations in Peripheral Blood and Airways following Lps Inhalation in Healthy Volunteers

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Regulation of Cyclooxygenase-2 and TGF-β1 by Hypoxia in Peripheral Pulmonary Artery Smooth Muscle Cells

KKK Sheares; XD Yang; NW Morrell

Clin Sci (Lond) (2002) 103 (s47): 59P.

View Articletitled, Regulation of Cyclooxygenase-2 and TGF-β1 by Hypoxia in Peripheral Pulmonary Artery Smooth Muscle Cells

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Agonist-specific Temporal Characteristics of β₂-Adrenoceptor-Stimulated Gene Transcription Response in CHO-K1 Cells Transfected with the Human β₂-Adrenoceptor

GJ Baker; IP Hall; SJ Hill

Clin Sci (Lond) (2002) 103 (s47): 59P–60P.

View Articletitled, Agonist-specific Temporal Characteristics of β2-Adrenoceptor-Stimulated Gene Transcription Response in CHO-K1 Cells Transfected with the Human β2-Adrenoceptor

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Gestation-Specific Regulation of Mmp and Timp Expression in Rat Uterine Artery in Pregnancy

B.A. Kelly; B.C. Bond; S.J. Pickering; L. Poston

Clin Sci (Lond) (2002) 103 (s47): 60P.

View Articletitled, Gestation-Specific Regulation of Mmp and Timp Expression in Rat Uterine Artery in Pregnancy

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Cross-Talk between Progesterone Receptor and C/EBPβ Isoforms in Differentiating Human Endometrium

Mark Christian; Birgit Gellersen; JAN Brosens

Clin Sci (Lond) (2002) 103 (s47): 60P.

View Articletitled, Cross-Talk between Progesterone Receptor and C/EBPβ Isoforms in Differentiating Human Endometrium

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Novel Polymorphisms in the Angiotensin II type 2 Receptor Gene: Common Haplotypes and Implications for Intrauterine Growth Restriction (IUGR)

Clare Tower; Sally Plummer; Pedro Alonso; Linda Morgan; Philip Baker; Noor Kalsheker

Clin Sci (Lond) (2002) 103 (s47): 60P–61P.

View Articletitled, Novel Polymorphisms in the Angiotensin II type 2 Receptor Gene: Common Haplotypes and Implications for Intrauterine Growth Restriction (IUGR)

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Human Myometrial Contractility: The Influence of Hypoxia

GJ Bugg; PN Baker; JM Taggart

Clin Sci (Lond) (2002) 103 (s47): 61P.

View Articletitled, Human Myometrial Contractility: The Influence of Hypoxia

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Human Myometrium: How Much Stretch Produces Maximal Contractility? is Gestation Important?

GJ Bugg; PN Baker; MJ Taggart

Clin Sci (Lond) (2002) 103 (s47): 61P.

View Articletitled, Human Myometrium: How Much Stretch Produces Maximal Contractility? is Gestation Important?

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MUC1 and Endometrial Receptivity

AW Horne; E-N Lalani; RA Margara; TA Ryder; JO White

Clin Sci (Lond) (2002) 103 (s47): 61P–62P.

View Articletitled, MUC1 and Endometrial Receptivity

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Ischaemic Burden following Traumatic Brain Injury: Monitoring Correlates and Relevance to Outcome

JP Coles; TD Fryer; DA Parry; P. Smieleswiksi; J. Matthews; T. Donovan; D. Day; F. Aigbrhio; JC Clark; JD Pickard; DK Menon

Clin Sci (Lond) (2002) 103 (s47): 62P.

View Articletitled, Ischaemic Burden following Traumatic Brain Injury: Monitoring Correlates and Relevance to Outcome

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Linkage Analysis between Childhood Absence Epilepsy and Genes Encoding GABA_A and GABA_B Receptors

Robert Robinson; Nichole Taske; Armin Heils; Thomas Sander; Michele Rees; Mark Gardiner

Clin Sci (Lond) (2002) 103 (s47): 62P.

View Articletitled, Linkage Analysis between Childhood Absence Epilepsy and Genes Encoding GABAA and GABAB Receptors

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Multiple Deaths due to Homoplasmic Mitochondrial DNA Mutations

R. McFarland; K.M. Clark; A.A.M. Morris; R.W. Taylor; R.N. Lightowlers; D.M. Turnbull

Clin Sci (Lond) (2002) 103 (s47): 62P–63P.

View Articletitled, Multiple Deaths due to Homoplasmic Mitochondrial DNA Mutations

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Electrical Impedance Tomography of Neonatal Brain Activity

A T Tidswell; JS Wyatt; RH Bayford; DS Holder

Clin Sci (Lond) (2002) 103 (s47): 63P.

View Articletitled, Electrical Impedance Tomography of Neonatal Brain Activity

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Sleep and Behavioural Changes after Adenotonsillectomy

HS Heussler; D Bramble

Clin Sci (Lond) (2002) 103 (s47): 63P.

View Articletitled, Sleep and Behavioural Changes after Adenotonsillectomy

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Continuities and Associations of Childhood Developmental Behaviour Problems

HS Heussler; L Polnay; U Cl; C Hollis

Clin Sci (Lond) (2002) 103 (s47): 63P–64P.

View Articletitled, Continuities and Associations of Childhood Developmental Behaviour Problems

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The Effect of Serotonergic Dysfunction and Hypercortisolaemia on the Neural Correlates of Episodic Memory and Executive Function

R.H. McAllister-Williams; M. Garside; F.C. Hsu; A.E. Massey; M.D. Rugg

Clin Sci (Lond) (2002) 103 (s47): 64P.

View Articletitled, The Effect of Serotonergic Dysfunction and Hypercortisolaemia on the Neural Correlates of Episodic Memory and Executive Function

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PET Measurement of the Influence of Corticosteroids on Serotonin-1A Receptor Number

AJ Montgomery; CJ Bench; AH Young; A Hammers; Z Bhagwagar; PM Grasby

Clin Sci (Lond) (2002) 103 (s47): 64P.

View Articletitled, PET Measurement of the Influence of Corticosteroids on Serotonin-1A Receptor Number

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Non-adherence to Immunosuppressants in Renal Transplant Recipients

JA Butler; RC Peveler; P Roderick; R Horne

Clin Sci (Lond) (2002) 103 (s47): 64P.

View Articletitled, Non-adherence to Immunosuppressants in Renal Transplant Recipients

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State and Trait Abnormalities in Serotonin Function in Major Depression

Z Bhagwagar; R Whale; PJ Cowen

Clin Sci (Lond) (2002) 103 (s47): 65P.

View Articletitled, State and Trait Abnormalities in Serotonin Function in Major Depression

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A Susceptibility Region for Autism on Chromosome 2: Linkage Disequilibrium Screen and Candidate Gene Studies

L Gallagher; S Ennis; JNG Wanjing; G Keaney; M Fitzgerald; R Stallings; DE Barton; AJ Green; M Gill

Clin Sci (Lond) (2002) 103 (s47): 65P.

View Articletitled, A Susceptibility Region for Autism on Chromosome 2: Linkage Disequilibrium Screen and Candidate Gene Studies

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Fmri Imaging of Verbal Self Monitoring in Monozygotic Twins Discordant for Schizophrenia

MM Picchioni; XA Chitnis; FU Chy; N Vythelingum; C Andrew; T Toulopoulou; SCR Williams; RM Murray; PK McGuire

Clin Sci (Lond) (2002) 103 (s47): 65P.

View Articletitled, Fmri Imaging of Verbal Self Monitoring in Monozygotic Twins Discordant for Schizophrenia

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Vascular Risk and Cognitive Impairment in An Older Caribbean-Born Population

R. Stewart; M. Richards; C. Brayne; A. Mann

Clin Sci (Lond) (2002) 103 (s47): 65P–66P.

View Articletitled, Vascular Risk and Cognitive Impairment in An Older Caribbean-Born Population

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Antidepressants Increase Intracellular Concentration of Cortisol by Modulating a Membrane Steroid Transporter

C.M. Pariante; A. Makoff; R.W. Kerwin

Clin Sci (Lond) (2002) 103 (s47): 66P.

View Articletitled, Antidepressants Increase Intracellular Concentration of Cortisol by Modulating a Membrane Steroid Transporter

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Investigating a Role for Peripheral Myelin Protein 22 as An Autoantigen in Guillain-Barré Syndrome

J Pritchard; RAC Hughes; NA Gregson; AC Hayday

Clin Sci (Lond) (2002) 103 (s47): 66P.

View Articletitled, Investigating a Role for Peripheral Myelin Protein 22 as An Autoantigen in Guillain-Barré Syndrome

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Decreased Concentration of Apolipoproteine in the Cerebrospinal Fluid after Acute Brain Injury

AD Kay; Nicoll Jarn

Clin Sci (Lond) (2002) 103 (s47): 66P–67P.

View Articletitled, Decreased Concentration of Apolipoproteine in the Cerebrospinal Fluid after Acute Brain Injury

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The Incidence and Heterogeneity of Idiopathic Parkinson's Disease in Cambridgeshire

Thomas Foltynie

Clin Sci (Lond) (2002) 103 (s47): 67P.

View Articletitled, The Incidence and Heterogeneity of Idiopathic Parkinson's Disease in Cambridgeshire

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Long-Term Survival of Porcine Expanded Neural Precursors in the Rat Model of Parkinson's Disease

T. Harrower; E. Ratcliffe; A Richards; S. Dunnett; R. Bark

Clin Sci (Lond) (2002) 103 (s47): 67P.

View Articletitled, Long-Term Survival of Porcine Expanded Neural Precursors in the Rat Model of Parkinson's Disease

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Boundary Formation in the Developing Chick Forebrain: A Possible Role for the Neuronal Leucine Rich Repeat Proteins

LC Andreae; J. Gilthorpe; A Lumsden

Clin Sci (Lond) (2002) 103 (s47): 67P–68P.

View Articletitled, Boundary Formation in the Developing Chick Forebrain: A Possible Role for the Neuronal Leucine Rich Repeat Proteins

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Autoantibodies to the Muscle Specific Kinase, MuSK in Myasthenia Gravis seronegative for Acetylcholine Receptor Antibodies

J McConville; W Hoch; J Newsom-Davies; D Beeson; A Vincent

Clin Sci (Lond) (2002) 103 (s47): 68P.

View Articletitled, Autoantibodies to the Muscle Specific Kinase, MuSK in Myasthenia Gravis seronegative for Acetylcholine Receptor Antibodies

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Cellular Models of Huntington's Disease

C. Turner; M. Orth; L. Jones; JM Cooper; AHV Schapira

Clin Sci (Lond) (2002) 103 (s47): 68P.

View Articletitled, Cellular Models of Huntington's Disease

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The Molecular Basis for Aberrant Gene Regulation in Friedreich's ataxia

CM Everett; A. Saveliev; Z. Webster; R. Festenstein

Clin Sci (Lond) (2002) 103 (s47): 68P–69P.

View Articletitled, The Molecular Basis for Aberrant Gene Regulation in Friedreich's ataxia

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Neuroserpin Phenotypes in Transgenic Drosophila are Rescued by the Alzheimer's β-amyloid peptide: In Vitro and in Vivo Correlations

Damian C. Crowther; Didier Belorgey

Clin Sci (Lond) (2002) 103 (s47): 69P.

View Articletitled, Neuroserpin Phenotypes in Transgenic Drosophila are Rescued by the Alzheimer's β-amyloid peptide: In Vitro and in Vivo Correlations

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The Role of Thrombophilias in Retinal Artery Occlusion: A Pilot Study

S Sastry; MKM Arshad; J Hardicre; D Taberner; D McLeod; CN McCollum

Clin Sci (Lond) (2002) 103 (s47): 69P.

View Articletitled, The Role of Thrombophilias in Retinal Artery Occlusion: A Pilot Study

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Mutations in COL8A2, the Gene Encoding the α2 Chain of Type VIII Collagen, Cause Two Forms of Corneal Endothelial Dystrophy

Graeme C. M. Black; Susmito Biswas; Francis L. Munier; Edwin. M. Stone; Richard Bonshek; David McLeod

Clin Sci (Lond) (2002) 103 (s47): 69P–70P.

View Articletitled, Mutations in COL8A2, the Gene Encoding the α2 Chain of Type VIII Collagen, Cause Two Forms of Corneal Endothelial Dystrophy

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11β-Hydroxysteroid Dehydrogenases, Aqueous Humour Corticosteroids, and Glaucoma

S Rauz; EA Walker; PJ Wood; PI Murray; PM Stewart

Clin Sci (Lond) (2002) 103 (s47): 70P.

View Articletitled, 11β-Hydroxysteroid Dehydrogenases, Aqueous Humour Corticosteroids, and Glaucoma

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Modeling Human Proliferative Vitreoretinopathy (PVR): The Commonest Cause of Anatomical Failure in Retinal Detachment (RD)

C S Sethi; G P Lewis; D G Charteris; S K Fisher

Clin Sci (Lond) (2002) 103 (s47): 70P.

View Articletitled, Modeling Human Proliferative Vitreoretinopathy (PVR): The Commonest Cause of Anatomical Failure in Retinal Detachment (RD)

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Areca Gastritis: A New Clinical Entity in Patients with Oral Submucous Fibrosis (OSF)

C. Trivedy; A. Forbes; S. Warnakulasuriya; IC Talbot; TJ Peters

Clin Sci (Lond) (2002) 103 (s47): 70P–71P.

View Articletitled, Areca Gastritis: A New Clinical Entity in Patients with Oral Submucous Fibrosis (OSF)

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Effect of Areca Nut on Salivary Copper in Chronic Chewers

KB Raja; C Trivedy; V Hazarey; S Warnakulasuriya; TJ Peters

Clin Sci (Lond) (2002) 103 (s47): 71P.

View Articletitled, Effect of Areca Nut on Salivary Copper in Chronic Chewers

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Microleakage of Four Pulp Protection Agents Placed in Vivo Under Class V amalgam Restorations¹

L.A. Morrow

Clin Sci (Lond) (2002) 103 (s47): 71P.

View Articletitled, Microleakage of Four Pulp Protection Agents Placed in Vivo Under Class V amalgam Restorations1

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Molecular Signalling during Calvarial Bone and Suture Development

David Rice; Ritva Rice; Irma Thesleff

Clin Sci (Lond) (2002) 103 (s47): 71P.

View Articletitled, Molecular Signalling during Calvarial Bone and Suture Development

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Genetic Studies of a Novel Cleft Palate Gene

MSU Hassan; DT Bonthron; AF Markham

Clin Sci (Lond) (2002) 103 (s47): 72P.

View Articletitled, Genetic Studies of a Novel Cleft Palate Gene

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Developmental Mechanisms Underlying Polydactyly

Miss A Crick; RJM Brown; GM Morriss-Kay

Clin Sci (Lond) (2002) 103 (s47): 72P.

View Articletitled, Developmental Mechanisms Underlying Polydactyly

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Identification and Utilisation of the ORF 73 Latency-Associated Regulatory Region in Herpesvirus Saimiri-Based Vectors

Mathew Giles; Peter Smith; Kersten Hall; Adrian Whitehouse

Clin Sci (Lond) (2002) 103 (s47): 72P.

View Articletitled, Identification and Utilisation of the ORF 73 Latency-Associated Regulatory Region in Herpesvirus Saimiri-Based Vectors

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β₁ NOT β₂ Integrins Regulate Macrophage Clearance from the Inflamed Site

G.J. Bellingan; P. Xu; H. Cooksley; S.E. Mutsaers; G.J. Laurent

Clin Sci (Lond) (2002) 103 (s47): 73P.

View Articletitled, β1 NOT β2 Integrins Regulate Macrophage Clearance from the Inflamed Site

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The Anti-Inflammatory Properties of Monoclonal Antibody 7E3, Parent Molecule of the Gpiib/IIIa Inhibitor Abciximab, Are Stimulus Specific

R Yadav; S Nourshargh

Clin Sci (Lond) (2002) 103 (s47): 73P.

View Articletitled, The Anti-Inflammatory Properties of Monoclonal Antibody 7E3, Parent Molecule of the Gpiib/IIIa Inhibitor Abciximab, Are Stimulus Specific

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Antibody Targeted Gene Transfer to Endothelium; a Strategy to Target Inflammatory Sites

P H Tan; M Manunta; N Ardjomand; SA Xue; DFP Larkin; DO Haskard; KM Taylor; AJT George

Clin Sci (Lond) (2002) 103 (s47): 73P.

View Articletitled, Antibody Targeted Gene Transfer to Endothelium; a Strategy to Target Inflammatory Sites

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Soluble Plasma P-Selectin but Not Platelet Expressed P-Selectin is Elevated in Patients with Advanced Carcinoma

I. McAllister; G.M. Spence; A.N.J. Graham; K.G. McManus; J.L. Ritchie; M.A. Armstrong; H.D. Alexander; F.C. Campbell; J.A. McGuigan

Clin Sci (Lond) (2002) 103 (s47): 74P.

View Articletitled, Soluble Plasma P-Selectin but Not Platelet Expressed P-Selectin is Elevated in Patients with Advanced Carcinoma

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Novel Contrast Agents for Magnetic Resonance Imaging of Inflammation

PR Reynolds; DOH Haskard; JV Hajnal; AD Edwards; AJT George

Clin Sci (Lond) (2002) 103 (s47): 74P.

View Articletitled, Novel Contrast Agents for Magnetic Resonance Imaging of Inflammation

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Pro-Adhesive Effects of Staphylococcal Lipoteichoic Acid on Leukocyte Trafficking In Vivo.

SJ Finney; PB Anning; T Hartung; TW Evans; A Burke-Gaffney

Clin Sci (Lond) (2002) 103 (s47): 74P.

View Articletitled, Pro-Adhesive Effects of Staphylococcal Lipoteichoic Acid on Leukocyte Trafficking In Vivo.

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Regulation of Fgf8 Expression by the Androgen Receptor in Human Prostate Cancer

VJ Gnanapragasm; CN Robson; DE Neal; HY Leung

Clin Sci (Lond) (2002) 103 (s47): 75P.

View Articletitled, Regulation of Fgf8 Expression by the Androgen Receptor in Human Prostate Cancer

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A Novel Mechanism of Tumour Immune Escape in Bladder Cancer

J Cresswell; H Robertson; D E Neal; J A Kirby

Clin Sci (Lond) (2002) 103 (s47): 75P.

View Articletitled, A Novel Mechanism of Tumour Immune Escape in Bladder Cancer

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Mitomycin C Acts through a p53 Dependent Pathway in Transtional Carcinoma of Bladder (TCCB)

J.J. McKnight; S.R. Johnston; K. Arthur; K.E. Williamson

Clin Sci (Lond) (2002) 103 (s47): 75P–76P.

View Articletitled, Mitomycin C Acts through a p53 Dependent Pathway in Transtional Carcinoma of Bladder (TCCB)

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Association between Breast-Feeding and Growth in Childhood through to Adulthood

Richard Martin; Gunnell David; George Davey Smith

Clin Sci (Lond) (2002) 103 (s47): 76P.

View Articletitled, Association between Breast-Feeding and Growth in Childhood through to Adulthood

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Association between Body Mass Index and Coronary Artery Calcification Score – Real Or Artefact?

E Hall

Clin Sci (Lond) (2002) 103 (s47): 76P.

View Articletitled, Association between Body Mass Index and Coronary Artery Calcification Score – Real Or Artefact?

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Do Ultramolecular Homoeopathic Dilutions Have Any Observable Clinical Effect? a Randomised, Double Blind Clinical Trial Using the Proving of Belladonna C30 as a Model

S B Brien, MsC PhD; G T Lewith, MA DM FRCP MRCGP

Clin Sci (Lond) (2002) 103 (s47): 76P.

View Articletitled, Do Ultramolecular Homoeopathic Dilutions Have Any Observable Clinical Effect? a Randomised, Double Blind Clinical Trial Using the Proving of Belladonna C30 as a Model

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Xenon Sedation in Intensive Care

A Bedi

Clin Sci (Lond) (2002) 103 (s47): 76P–77P.

View Articletitled, Xenon Sedation in Intensive Care

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Issues

Cover Image

Medical Research Society Meeting 4 February 2002

Communication