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Review Articles
Nrf2 in health and disease: current and future clinical implications
Othman Al-Sawaf; Tim Clarner; Athanassios Fragoulis; Yuet Wai Kan; Thomas Pufe; Konrad Streetz; Christoph Jan Wruck
Clin Sci (Lond) (2015) 129 (12): 989–999.
Immunometabolism of obesity and diabetes: microbiota link compartmentalized immunity in the gut to metabolic tissue inflammation
Clin Sci (Lond) (2015) 129 (12): 1083–1096.
Pathogenic aspects and therapeutic avenues of intestinal fibrosis in Crohn's disease
Clin Sci (Lond) (2015) 129 (12): 1107–1113.
Cellular and molecular mechanisms of HGF/Met in the cardiovascular system
Clin Sci (Lond) (2015) 129 (12): 1173–1193.
Hypotheses
PARK7/DJ-1 dysregulation by oxidative stress leads to magnesium deficiency: implications in degenerative and chronic diseases
Martin Kolisek; Augusto C. Montezano; Gerhard Sponder; Aikaterini Anagnostopoulou; Juergen Vormann; Rhian M. Touyz; Joerg R. Aschenbach
Clin Sci (Lond) (2015) 129 (12): 1143–1150.
Original Papers
Enhanced cough reflex in a model of bleomycin-induced lung fibrosis in guinea pigs
Joan Antoni Fernández-Blanco; Mònica Aguilera; Anna Domènech; Gema Tarrasón; Neus Prats; Montse Miralpeix; Jorge De Alba
Clin Sci (Lond) (2015) 129 (12): 1001–1010.
Klotho expression is reduced in COPD airway epithelial cells: effects on inflammation and oxidant injury
Wei Gao; Cheng Yuan; Jingying Zhang; Lingling Li; Like Yu; Coen H. Wiegman; Peter J. Barnes; Ian M. Adcock; Mao Huang; Xin Yao
Clin Sci (Lond) (2015) 129 (12): 1011–1023.
Inflammation-induced microvascular insulin resistance is an early event in diet-induced obesity
Clin Sci (Lond) (2015) 129 (12): 1025–1036.
Insulin growth factor-1 (IGF-1) enhances hippocampal excitatory and seizure activity through IGF-1 receptor-mediated mechanisms in the epileptic brain
Clin Sci (Lond) (2015) 129 (12): 1047–1060.
Phosphodiesterase 1 regulation is a key mechanism in vascular aging
Paula K. Bautista Niño; Matej Durik; A.H. Jan Danser; René de Vries; Usha M. Musterd-Bhaggoe; Marcel E. Meima; Maryam Kavousi; Mohsen Ghanbari; Jan H. Hoeijmakers; Christopher J. O'Donnell; Nora Franceschini; Ger M.J. Janssen; Jo G.R. De Mey; Yiwen Liu; Catherine M. Shanahan; Oscar H. Franco; Abbas Dehghan; Anton J.M. Roks
Clin Sci (Lond) (2015) 129 (12): 1061–1075.
Modified high-intensity interval training reduces liver fat and improves cardiac function in non-alcoholic fatty liver disease: a randomized controlled trial
Kate Hallsworth; Christian Thoma; Kieren G. Hollingsworth; Sophie Cassidy; Quentin M. Anstee; Christopher P. Day; Michael I. Trenell
Clin Sci (Lond) (2015) 129 (12): 1097–1105.
Release of insulin from PLGA–alginate dressing stimulates regenerative healing of burn wounds in rats
Sandeep Dhall; João P. Silva; Yan Liu; Michael Hrynyk; Monika Garcia; Alex Chan; Julia Lyubovitsky; Ronald J. Neufeld; Manuela Martins-Green
Clin Sci (Lond) (2015) 129 (12): 1115–1129.
Increased ubiquitination and reduced plasma membrane trafficking of placental amino acid transporter SNAT-2 in human IUGR
Yi-Yung Chen; Fredrick J. Rosario; Majida Abu Shehab; Theresa L. Powell; Madhulika B. Gupta; Thomas Jansson
Clin Sci (Lond) (2015) 129 (12): 1131–1141.
Histone acetylation regulates orphan nuclear receptor NR4A1 expression in hypercholesterolaemia
Clin Sci (Lond) (2015) 129 (12): 1151–1161.
LDL-lipids from patients with hypercholesterolaemia and Alzheimer's disease are inflammatory to microvascular endothelial cells: mitigation by statin intervention
Clin Sci (Lond) (2015) 129 (12): 1195–1206.
Plic-1, a new target in repressing epileptic seizure by regulation of GABAAR function in patients and a rat model of epilepsy
Clin Sci (Lond) (2015) 129 (12): 1207–1223.
miR-21 promotes renal fibrosis in diabetic nephropathy by targeting PTEN and SMAD7
Aaron D. McClelland; Michal Herman-Edelstein; Radko Komers; Jay C. Jha; Catherine E. Winbanks; Shinji Hagiwara; Paul Gregorevic; Phillip Kantharidis; Mark E. Cooper
Clin Sci (Lond) (2015) 129 (12): 1237–1249.
Commentaries
Cyclic nucleotide phosphodiesterase 1 and vascular aging
Clin Sci (Lond) (2015) 129 (12): 1077–1081.